Exciting @centuri-ls.bsky.social internal seminar by @efeilker-phys.bsky.social on energetics and scaling during development 🤩

🚨 Exciting conference for stem cell aficionados! ‘Frontiers in Stem Cell Innovation’ will bring together experts in stem cell biology from academia & industry to discuss key developments as well as challenges in regenerative medicine and disease modelling. fisci2026.eventbrite.co.uk Please repost 🙏

1/ 🚀 AEBP2 isn’t what we thought. You were told that AEBP2 promotes PRC2 activity on chromatin. We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity. 👉 surl.li/cgwqcq A thread 🧵

Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176 #biophysics

📢 New preprint ! Please check if you are interested in the comparison between 2d and 3d nematic theories 🤔 I show that the 2d description can lead to artefacts on curved surfaces, and I propose a thin film description of nematic shells with full 3d orientation ! This was a funny summer project 😊

Check out our new work, led by talented @janhuemar.bsky.social, where we uncover that pioneer factor Oct4 remodels chromatin for DNA access not by opening it but by exploiting nucleosome breathing and forming clusters 🔥🔥🔥

The Paris Agreement offers a powerful framework for a fairer, healthier world. But as extreme heat shows, every tenth of a degree matters. We need higher ambition to stop violating the rights of ever more people. - new @wwattribution.bsky.social study www.worldweatherattribution.org/ten-years-of...

This work was led by Young Jun Kim, a very talented student in the lab. If you have ONT data and want to investigate DNA methylation, DMRcaller would be able to provide you more information than what was previously possible.

Biophysics Seminar will take place Today, 12pm, at ENS Physics Department, room L378 ( zoom link by DM). Fabián Aguirre López (Centre d'Economie de la Sorbonne). Patterns robust to Disorder in spatially-interacting Generalized Lotka-Volterra Ecosystems

Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team! Please repost! jobs.jic.ac.uk/Details.asp?...

If you are a computational biologist come, apply and join Howard & Klose lab in a joint Norwich-Oxford collaboration on chromatin dynamics!

If you are a computational biologist interested in how chromatin states are established and maintained to regulate transcription, this is the dream job for you! This will be in close collaboration with the Klose lab in Oxford and we have a lot of cool projects you can get involved in. Apply!

After a long time in the making, my paper on nonequilibrium thermodynamics of Darwinian evolution has been published in Philosophical Transactions B. Updated version: arxiv.org/abs/2112.02809

Very exciting opportunity for those with a quantitative background and interested in epigenetics / gene regulation. Highly collaborative environment!

New preprint from the lab !! Loop extrusion may provide mechanical robustness to chromatin. Great work by Hossein Salari. @cnrs.fr @lbmcinlyon.bsky.social www.biorxiv.org/content/10.1...

I'm really looking forward to visiting Norwich again and sharing my perspective on why plants are the most amazing and important organisms in the universe! 🌱💚

Delighted to share that I’ve been awarded the Wellcome Trust Early-Career Award 🙏 £1.4m over 5 years. The start of an exciting new journey 🚀

NEWS - Talented early-career researcher receives major @wellcometrust.bsky.social funding The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity. www.jic.ac.uk/news/talente...

Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...

I wrote an "Open Questions" piece last year, trying to sum up things I have been thinking about on gene tuning and TFs dosage. In my view, much we don't know is cause we are lacking the tools - but maybe I'm biased as I was a tech developer. THX to the reviewer! :) doi.org/10.1098/rsob...

🚨 New paper alert 🚨 I am excited to share our new work on epigenetic enhancer priming in early mammalian development genomebiology.biomedcentral.com/articles/10.... Fantastic collaboration with Wolf Reik’s team, with key contributions from many others, led by the excellent Chris Todd. Short 🧵

🇪🇺🤝 🇰🇷 Today, the Republic of Korea joins Horizon Europe. It is the first Asian country to take part. Korean entities can now join and lead research consortia with some of the world’s best research organisations to tackle global challenges together. More info ↓ europa.eu/!QFHCnC

Save the Date! Development has teamed up with the Wellcome-funded consortium the Human Developmental Biology Initiative to co-organise a meeting on #HumanDevelopment. 📅7 - 9 Sep 2026 📍University of Warwick, UK Register your interest for #HumanDev26: www.biologists.com/meetings/dev...

The functional importance of RNA structure in plant domestication😊

Super pleased our @jxbotany.bsky.social review with Pablo González-Suárez @pablidopsis.bsky.social (now with Margot Smit), Tom Lock @txmlock.bsky.social and Steve Penfield (@johninnescentre.bsky.social) on plant architecture responses to seasonal temperature is out! academic.oup.com/jxb/advance-...

We have a @royalsociety.org funded PhD studentship available in the Morgan group: ‘Investigating the influence of temperature on meiotic recombination’: www.findaphd.com/phds/project... 🗓️ Closing date: 21 July 2025

Registration for Transcription and Chromatin UK is OPEN! Taking place from September 17 to 19, 2025, this conference will showcase cutting-edge research and is a ‘must-attend’ event for the UK transcription and chromatin community & both at home and abroad. Pl register ow.ly/7QQb50W9Alo & share

UK media is so wild. It is tough to properly convey how shockingly deceptive this article is. It's desperate I guess but a lot of people will still read this, and trust it bc it's coming from what looks to be a reputable media outlet. archive.ph/1z7Ie

Please RT ! 5️⃣ days left to register. Gordon Conference “Histone and DNA modifications” Tuscany 🇮🇹 20.-25. July 25 🗓️ Regulation of genome function by histone and nucleic acid modifications. Great speaker lineup !!! >25 talks will be chosen from abstracts. Submit yours ➡️ shorturl.at/hBjyT

Very enjoyable event indeed! Thanks a lot to the organisers for such a wonderful meeting!

Really looking forward to @radaiglesiaslab.bsky.social's talk on "Gaining mechanistic insights into long-range gene regulation through synthetic biology approaches" in @enhancedgenomics.bsky.social's seminar series. 📅 June 5th 2025 tomorrow ⏰ 4pm GMT Please join us: us02web.zoom.us/webinar/regi...

Delighted & excited to share our latest preprint on non-canonical enhancers in human pluripotent stem cells, the result of a fantastic and fun collaboration with @guenesdoganlab.bsky.social‬: www.biorxiv.org/content/10.1... 🧵 below

The cloud is a wonderful concept

Happy to share that our study of inheritance of homoeolog expression bias in wheat biparental populations is out in @biomedcentral.bsky.social Genome Biology! 🧬 Many thanks to all co-authors and @philippaborrill.bsky.social for great leadership on the project! #PlantScience #Botany rdcu.be/eokf2

Just dropping this here in case anyone is interested in joining 🙃

The Crick is paying £800,000 in visa fees alone. Britain is choosing to turn inwards, away from the world, and to destroy its own future. That is not Britain. observer.co.uk/news/politic...

I've known Akis @akispapantonis.bsky.social since our early postdoc days when we were both studying transcription factories. He's an outstanding scientist and excellent speaker - highly recommended! Join us tomorrow!

El marco ya está listo: la culpa del apagón la tiene la izquierda ecologista por favorecer las renovables e ir contra las nucleares. Ahora, a machacar con él por tierra, mar y aire hasta instalarlo en las cabezas de la gente.

🚨 new preprint from the lab. Combining modeling, new Hi-C data in yeast and data analysis, our study offers new insights into the spatial and dynamic organization of chromatin during replication in eukaryotes. Check the tweetorial below ⬇️ www.biorxiv.org/content/10.1...

The 2025 NBI postdoc retreat is currently underway. We've so far heard of the leap from academia to industry, careers in the civil service and editing, and navigating a career in academia. Wonderful experiences all!Looking forward to the workshop this afternoon! @johninnescentre.bsky.social

This also shows that classical Euclidean geometry is not only a pastime for the upper classes of the Victorian era or contestants in mathematical Olympiads!

The paper is now live: academic.oup.com/mbe/article/... Absolutely delighted to play a role in this fascinating story!

In 2024, Europe was the world’s fastest-warming continent. It had its hottest year on record, impacting an estimated 413,000 people. Sea surface temperatures also reached new highs. As our planet heats up, urgent action is more critical than ever.

New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇

I very much look forward to @mosterwalder.bsky.social's talk on "Functional architecture of cardiac TF regulatory landscapes in control of mammalian heart development" in 'The 3D Regulatory Genome', @enhancedgenomics.bsky.social's virtual seminar series. Join us at: us02web.zoom.us/webinar/regi...

And that was a wrap for #POL2025 @physicsoflifeuk.bsky.social. Great talks throughout the week, and looking forward to the 2027 edition!

1. Today the Tories unveil their new policy: ripping up the commitment to net zero by 2050. Kemi Badenoch, with no evidence, claims "it can’t be achieved without a serious drop in our living standards or by bankrupting us." What the evidence shows is the opposite. We can't prosper without it. 🧵

Our paper has been published! We used in vivo single-particle tracking to demonstrate that the assembly of core FCA oligomers into functional macromolecular condensates. Thanks to all the authors and colleagues!

🌊 Today in @nature.com: Is the AMOC on the brink of collapse? Unlikely before 2100—but the risks are real 🚨 We find Southern Ocean winds keep this vital ocean "heat engine" running, even under extreme #climatechange. But the Pacific holds a surprise… tinyurl.com/yt6u4e7d Let’s explore 🧪👇