Out @natcomms.nature.com: our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀 Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!). Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social rdcu.be/eIJm5

Hot off the press! Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 www.nature.com/articles/s41...

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

So proud of the exciting story from my PhD student Jakub Sumbal on contractile fibroblasts shaping branching morphogenesis! Fantastic collaboration with the lab of Zuzana Koledova in Prague! @sumbalovakoledova.bsky.social It just came out online, check it out here: rdcu.be/eIIKD

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...

Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

A multi-omics overview of perturbations in the #T1D pancreas at the single cell level #islets www.science.org/doi/10.1126/...

1/7 Really happy to see my PhD work published in ✨Developmental Cell✨ today! We find human endoderm is specified by two developmental trajectories 🔀, and the choice between alternate routes is dictated by the combinatorial BMP4/Activin signalling. www.cell.com/developmenta...

Walking through the night for Cancer Research UK 🌙✨ Every step helps beat cancer 💜 Please support with a donation if you can 🙏💫 fundraise.cancerresearchuk.org/page/rocios-...

🔬 Researchers at #IBEC record for the first time the real-time 3D implantation of a human embryo.  A major step forward in understanding fertility and improving assisted reproduction treatments. 👉 Published in @science.org #ScienceAdvances 🔗 Read the news: bit.ly/4oAHy0w

Pathologists have used nuclear & tissue shapes to diagnose #cancer for decades, but what is the molecular basis for this? In our latest work, we develop a computational pipeline to figure this out in #colorectalcancer! Check out 🧵& preprint #mechanobiology #stemcells www.biorxiv.org/content/10.1...

12 examples of how developmental biology research led to fundamental discoveries for biomedical research. There are many more! Download ppt & jpg versions on @socdevbio.bsky.social website. Use & modify as needed. Poster formats are also posted to print & hang in your lab!

Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch

Dev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social thenode.biologists.com/jobs/postdoc...

🆕🧪‼️ New lab preprint! We study how germ cells (the cells that give rise to gametes, in this case sperm) are supported by somatic (non-germ) cells of the gonad. This matters for our understanding of reproduction - without germ cell development, animals are sterile. www.biorxiv.org/content/10.1...

Excited to share our latest work with @jamesbriscoe.bsky.social . A global #cis-regulatory temporal program guides how spatial cues are interpreted in neural progenitors. We show how #space and #time can be integrated to generate cell type diversity in the #spinalcord. Congrats to all authors.

Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu

🧵Just out ! We reveal how 4 branched epithelia—mammary, lacrimal, salivary & prostate—use a conserved YAP–Notch–p63 circuit to self-organize during development & regeneration. Here’s the story👇 authors.elsevier.com/c/1lM285Sx5g... Work done in @frelab.bsky.social at ‪ ‪ @institutcurie.bsky.social

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

Organoids in a dish are next to one another. Treatment stops some of them from growing but their neighbours just keep going. What’s the difference? Hint: it’s not genetic doi.org/10.1101/2025...

🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨ “A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶 🔗 www.biorxiv.org/content/10.1... #devbio #biophysics 🧵⤵️

Male mouse fetuses can develop female organs in utero if their mother is iron deficient during pregnancy https://go.nature.com/43N7f4s

We are doing it again!! 🚶‍♀️🚶‍♂️🚶🧪🧫🔬 For the Second Year My Lab is participating to the One_Walk_London 🎡 to raise money for life-changing research & make a difference to T1D #diabetes ⤵️ support.breakthrought1d.org.uk/fundraisers/... Please help us raise funds for @breakthrought1duk.bsky.social

Our work on lineage tracing with somatic epimutations is finally out in @nature.com! Check out the thread by @larsplus.bsky.social below. EPI-clone is a revolutionary technique for lineage tracing and it will immediately impact how we trace clones everywhere. Detailed protocols coming out soon!

Happy to see the first bit of my postdoc work out! Have a look! 👀

Looking forward to hear about Dr. Vicki Metzis's research ( @vmetzis.bsky.social ) in today's CGTRM Stem cells @ Lunch seminar, 2PM BST!

ΔNP63 defines an exocrine-committed multipotent progenitor subset in the murine pancreas https://www.biorxiv.org/content/10.1101/2024.12.10.627728v1

Excited to hear about Dr. Aida Martinez research (@aidamartinezs.bsky.social) next CGTRM Stem cells @ Lunch seminar on Tuesday 10th Dec 2PM BST!

Researchers from the organoid group created a new organoid that mimics the human fetal pancreas. Unlike previous ones, this organoid has all three key cell types. They also identified a stem cell that develops into these cells. Curious?👉 www.hubrecht.eu/researchers-... @amandaanderssonr.bsky.social