Janssen, V., & Huveneers, S. (2024). Cell–cell junctions in focus–imaging junctional architectures and dynamics at high resolution. Journal of Cell Science, #EpithelialMechanicsReview doi.org/10.1242/jcs....

Mamdani: For too long, those fluent in the good grammar of civility have deployed decorum to mask agendas of cruelty

Happy 2026! May this year be good for your cells, Discovering all the cool #EpithelialMechanics as well.

James, J., Winn, L. B., Mottram-Epson, P., & Köster, D. (2025). Paths to stability–actin regulation of adherens junction mechanics. Journal of Cell Science, #EpitheilalMechanicsReview doi.org/10.1242/jcs....

Fully agree! + shameless advertisement of my own work in this context: Combining git(hub/lab) with AI is a way towards transparent AI usage and learning together how to use it right. www.nature.com/articles/s43...

Morphogenesis & Organogenesis! Part 1 (full) in the comments 👇 Comment if you'd like to be added (regardless of age or career stage!) Please post your own biology-related starter packs using #BioStarterPacks 🧬🔬🪰🐟🐁🌱

We're a bit late in ringing in the giving season, but it is indeed upon us. Enjoy our special edition holiday logo ☃️ and, if you can spare a bit and appreciate napari, please donate to our development efforts! 🙏 CZI will match donations up to $75K. opencollective.com/napari/donate

Teaching Academic life to cats, lesson 301: Funding Opportunities 💸🐈

Kim, S., Amini, R., Yen, S. T., Pospíšil, P., Boutillon, A., Deniz, I. A., & Campàs, O. (2024). A nuclear jamming transition in vertebrate organogenesis. Nature materials, 23(11), 1592–1599. #EpithelialMechanics buff.ly/lvEsDJG

In a paper out this month in @jcb.org we present evidence implicating intrinsically disordered regions (IDRs) as key to junctional assembly and function 2/n 🧪 pubmed.ncbi.nlm.nih.gov/41099653/

To build the body plan of an animal, cells must adhere to one another via cell-cell junctions. We now know these assemble as punctate protein complexes containing thousands of proteins, but how this occurs remains mysterious. 1/n 🧪 www.molbiolcell.org/doi/full/10....

Cells can sense the geometry of their environment, from tiny subcellular features to whole-tissue patterns. How can we engineer environments to systematically probe these responses? 🧵 I'm @lhinderling.bsky.social from @olivierpertz.bsky.social lab, let’s do a short tour on microfabrication!

#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you. www.biorxiv.org/content/10.6...

Vertebrates can use entirely different mechanisms to generate its anterior and posterior dorsal tissue. In this thorough review from the lab of Lance Davidson, different morphogenetic events are compared between the front and the back in a developing embryo. Check it out: doi.org/10.1016/j.cd...

Now #published @physrevlett.bsky.social: the answer to the question that Euler did not solve three hundred years ago*. @zhaoshh.bsky.social doi.org/10.1103/63py-ph5s * Possible reasons include not having access to Mathematica and predating Riemann (in the non-ecological sense).

It's finally out! Our paper on optogenetic interrogation of the lateral line: www.cell.com/iscience/ful... This one involved a lot of sweat and tears, and it was a real tour de force. It was also the last paper we got to write with Jim, so it's a special one (and hence, the tears).

From (slime) mold to man: #Talin plays a key role in animal cell adhesion and force transmission during locomotion. Check out exciting new paper by the Grashoff group @natcomms.nature.com : rdcu.be/eTFJR @uni-muenster.de

Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets | Nature Biotechnology share.google/fzkzh3rZEa53...

Cytoskeleton shapes tissues during development. What signaling drives these changes? I'm @onenimesa.bsky.social and let's explore FGF signaling's crucial role with examples. Trust me, you need to know this!

Non-invasive Biomechanical Characterization of Embryos Using Microfluidic Cantilevers https://www.biorxiv.org/content/10.64898/2025.12.02.691595v1

Hi bsky! How do cells coordinate fate with migration during development? 🐣 Turns out EMT doesn't just drive cell behaviour changes... it actively primes BMP signalling competence, creating a reciprocal coupling that drives collective invasion! (@bensteventon.bsky.social lab) tinyurl.com/2ncc8zap

Check out this work from @yuritakahashi.bsky.social that reveals reciprocal interactions between cell migration and fate specific to drive collective cell invasion. And follow Yuri at the same time

Thanks to Advanced Functional Materials for highlighting our work on their back cover!

🥳 Thrilled, honored & very happy to become part of the amazing EMBO Young Investigator Programme! Looking forward to the new opportunities, interactions, ideas & collaborations it will spark. Very grateful to my fantastic team @mpi-cbg.de, colleagues, collaborators & mentors who made this possible!

Tissue stress measurements — our latest preprint is out: arxiv.org/abs/2512.00550 (publication coming soon!) Fantastic work by the three musketeers — @luanger.bsky.social, @andreasschoenit.bsky.social and @fanny-wodrascka.bsky.social — in collaboration with P. Marcq!

New preprint! SOSEKI polarity proteins are mechanoresponsive integrators linking growth and tissue mechanics during lateral root formation. Their polarity marks growth boundaries and reorganises in response to mechanical alterations —reshaping how we think about axis formation. tinyurl.com/28p7af2w

FLASH-AWAY: Intrabody-Directed Targeting of Optogenetic Tools for Protein Degradation: pubs.acs.org/doi/10.1021/...

It is a nice way to end the week: our improved RAB GTPase BioID map now online! www.nature.com/articles/s42... We hope it will be useful to the community, and we're happy to share any reagents!

🫣 #LLPS #Droplets #phaseseparation

Thank you A. Perez-Ramos and P. Bovolenta for this great perspective on our article about Optic Cup morphogenesis @dev-journal.bsky.social !

Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰 We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila. I’ll soon hire my first #PhD student — feel free to reach out! #juniorPI #Science #devbio

It’s time to talk about epithelial geometry and cancer. How can the architecture of an epithelium affect how tumors will grow and spread? In this thread, @jorgealmagro.bsky.social

We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji. It ships many new features, detailed below, but that are articulated around the following:

#stuffthatmatters 👇

TEAD4 regulates apical domain homeostasis and cell-positioning to maintain the trophectoderm lineage during preimplantation mouse embryo development. https://www.biorxiv.org/content/10.1101/2025.11.18.689016v1

Version 2 is out! More comprehensive text plus new tissue- and pathway-specific analysis revealing how different viruses trigger systemic aging through diverse mechanisms. www.biorxiv.org/content/10.1...

I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...

Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease. #JCSciliaSI journals.biologists.com/jcs/article/...

Finally out in #PRXLife: our theory on the effect of temperature on the completion time of large networks. Using graph theory, one can show that the Arrhenius plot is quadratic, in excellent agreement with experimental data from fly development. Read the open access paper here: go.aps.org/48brig2

Today I lift up survivors of sexual violence. I am centering your pain, your need to see justice, your healing. I am so sorry for what happened and I am so sorry this country and world protect wealthy men who rape and abuse children and women. May they start to fear the truth.

In their Perspective article, Ruxandra Bachmann-Gagescu, and John Sayer explore how ciliary specialisation might explain the high variability of ciliopathies and propose priority research directions. #JCSciliaSI journals.biologists.com/jcs/article/...

Just out! Our work on active transport in epithelial tissues. Congrats to Huiqiong Wu, Greg Arkowitz and Ranjith Chilupuri in collaboration with C. Duclut and J. Prost! PNAS www.pnas.org/doi/10.1073/...

Now recruiting several PhD students and postdocs for different projects of our excellence cluster SynthImmune: application.synthimmune.de For more info see perspective article below and synthimmune.de

Beautiful beasts (2): Thanks Ian for allowing us to help a little to help you figuring out how B-cells help T-cells. What a spectacular cover coloured by #micronaut Martin Oeggerli.