@riley-research.bsky.social had a great time catching up with local research at the Cascadia Proteomics Symposium last week. The lineup featured talks from Katie Kothlow and Haley Schramm, and a lightning talk/poster from @emmajays.bsky.social Congrats to Emmajay for her 2nd-place poster award too!

This was so much fun! It was great to present and meet other incredible undergraduates at #ASMS2025. A huge thank you to @riley-research.bsky.social group members for their unwavering encouragement and even bringing me food and water during the presentations!

@riley-research.bsky.social is excited for #ASMS2025 in Baltimore! We made sure to capitalize on some of the classics, like a crab dinner at LP Steamers and an Orioles game, before the conference festivities kicked off. Come hear what we have been up to!

Join @lindsaykpino.com, me, and our amazing panelists for the #ASMS2025 #Chemoproteomics workshop on Monday!

🧪 #neurology #neuroskyence tinyurl.com/bp5d8386 Another beautiful example of NIH-SPONSORED bedside to bench and back to bedside work from an outstanding clinician scientist. This work is producing some of the most compelling responses to treatment in what is arguably the worst pediatric brain tumor.

We are lucky to have multiple people to celebrate in @riley-research.bsky.social recently. This time graduate student Kayla Markuson won 2 (!) @uwchemistry.bsky.social awards: - Outstanding Teaching Assistant Award - Excellence in Graduate Leadership and Service Award Way to go Kayla!

Massive congratulations to @nmriley.bsky.social on being named as a Searle Scholar! This is extraordinary. 🎉

I'm so grateful for the extraordinary mentorship from everyone in @riley-research.bsky.social on a daily basis, and leadership from @nmriley.bsky.social and my postdoc mentor @timveth.bsky.social in creating a highly intentional research experience for undergraduates in the group. Congrats to all!

Huge welcome to our new RRG undergraduates, so thrilled to work together!

Check out the first IPSA iteration here if you need to annotate any peptide MS/MS spectra: www.sciencedirect.com/science/arti...

Time for a proud PI post 🎉 : Katie Kothlow from @riley-research.bsky.social received an Honorable Mention from the National Science Foundation (NSF) Graduate Research Fellowship Program! Congrats, Katie!

Had an amazing time at the Glycobiology Gordon Research Seminar and Conference in Italy! 🇮🇹 As a first-time attendee, I appreciated meeting so many incredible scientists from across the world. We spent the days talking about carbohydrates, and the nights eating them. 🍝 #Glycobiology #Glycotime

A nearly 9 year effort to design and implement new CLIP-based technologies to define multimeric protein assemblies on RNA. Enables ‘watching’ of RNP assemblies inside living cells Special congrats to Luca Ducoli, Brian Zarnegar, and Paul Khavari @nature.com www.nature.com/articles/s41...

GlyCounter (and pre-print) from the @riley-research.bsky.social is now out to help inspect raw MS data for glycan-specific ions. Congrats to first author Katie Kothlow for leading this and to all RRG members who helped test GlyCounter's utility for numerous datasets! This was a great team effort.

Missed our March webinar with Dr. Nicholas Riley on glycoproteomics data analysis? Catch the full presentation on our YouTube channel! Learn about Glycounter, ADS technology, and new tools for interpreting complex glycopeptide MS spectra. Check it out: youtu.be/Y7yGFfYw3G0 #glycotime

The Glycobiology Gordon Research Seminar this weekend was a great kickoff to the Glyco GRC this week. ~70 grad students and postdocs shared awesome #glycotime data and built community. Much appreciation is owed to my co-chair @fionachembot.bsky.social who played a big role in its success.

One of the most significant and challenging projects of my career so far. PepCentric: a scalable computational platform utilizing novel 2-D fragment indexing for rapid peptide-centric searches, enabling proteogenomics searches against billions of spectra in seconds. www.biorxiv.org/content/10.1...

I'm incredibly fortunate to be a part of the team from @balynzaro.bsky.social's lab which just won first prize at the 2025 QBI Hackathon last weekend. Many congratulations to my mentor and team lead José Montaño and fearless research engineer Vee Xu. 🥇 #chemicalbiology

Congratulations to my incredible mentor, Dr. Nick Riley, on winning the 2025 Arthur F. Findeis Award for Achievements by a Young Analytical Scientist! Thank you for being a role model as an enthusiastic explorer of the unknown, developing the forefront of analytical chemistry to uncover #glycotime

Glycoscience Grenoble is supporting US colleaugrs @fionachembot.bsky.social @nmriley.bsky.social @carolynbertozzi.bskyverified.social

I am excited to discuss our efforts in @riley-research.bsky.social to help streamline glycoproteomics methods at the @glygen.bsky.social webinar next week!

It is important at this pivotal moment to @standupforscience.bsky.social. Looking forward to sharing my thoughts on why this should be a national priority at tomorrow’s rally in SF:

Congratulations to the 2025 Kolthoff Award Winners, all undergraduate scientists who receive support to present their work at Pittcon (this week!) or @acs.org Spring Meeting!: Vera Chen Erik Sveen Angelina Lo Presti Emerson Orlando Pérez Valdez Naina Beishembieva acsanalytical.org/2025/02/19/2...

I’ll definitely be at Civic Center Plaza this Friday to #StandUpForScience along with so many wonderful scientists from the Bay Area who are working tirelessly to defend and uphold our scientific communities - an immeasurable pillar for the public good @standupforscience.bsky.social #scienceforall

Highlights from our week include: Travel awards for Katie (graduate) and @vishnutejus.bsky.social (undergraduate) 🎉 Poster presentations by @emmajays.bsky.social y.social, Haley, Vishnu, and me. We had fun with our poster lightning talks, too! 1st place overall poster award to Katie! 🎉

Despite current events, @riley-research.bsky.social enjoyed @us-hupo.bsky.social last week! Connecting w/ colleagues was an antidote for the frustration that occupies a lot of my brain space these days Thanks for the continual motivation to pursue good science and support scientists however we can

Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA. Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...

More talents at the @us-hupo.bsky.social poster lighting talks blow our minds away

We updated our @riley-research.bsky.social website this weekend, including a new section on our Useful Links page that consolidates materials we found helpful in the current events discourse, re: funding cuts. Hopefully it can be a helpful resource: www.riley-research.com/useful-links

Congrats to Katie and Vishnu for their travel awards!

👀 I spy @riley-research.bsky.social members there! Congrats to all!

My favorite takeaway from #USHUPO2025 so far?! Building a business is not too different from building a lab. Huge thanks to @lindsaykpino.com & @nmriley.bsky.social for hosting a phenomenal workshop on the business of starting a lab!!!

Let me give a concrete example of the importance of applications with high risk-high reward as well as the role of NIH staff in taking risks. Decades ago, a physical chemist proposed ideas about doing mass spectrometry on proteins (when this was deemed probably impossible). 1/n

awesome read. Dr. Claire Clelland @ucsf @clellandlab.bsky.social an inspiring physician-scientist in the business of changing what’s possible @mdphdequity.bsky.social

“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.” www.researchamerica.org/2023-oped-us...

I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅 #sciart #blender3d #biocatalysis

Highlighting this RRG update in case it can be useful for anyone. One tangent from this, re: #glycotime conferences... it is a bummer GRCs for Glycobiology, Carbohydrates, CAZymes, and Bioorganic Chemistry all occur in the same year/cycle. Carb and Bioorg Chem even fall on the same week this year!

Can I just say, I love that we can have conversations again about things like our views on O-chem on #bluesky. I really missed proper debate and discussion of science. ❤️@pauldauenhauer.bsky.social @justingallivan.bsky.social @jenlove.bsky.social

Saying ‘I don’t know’ in talks has become a lost art, unfortunately. Super interesting discussions require us to be open about what we don’t know and what still needs to be explored. Here’s my recipe for answering questions in talks:

Hi All, Just joined Bluesky! @carolynbertozzi.bsky.social @czerwinsmarcin.bsky.social @benschulz.bsky.social @glyco.me Looking forward to the #glycotime here!

1/ Hi 🦋! Did you know? Glycans—complex sugar structures—decorate almost every protein processed by the ER/Golgi. These N-glycans coat our cells, playing critical roles in cell interactions and immune processes. 🍬 Curious about how they vary? Let’s dive in! #GlycoTime

Hello friends! Just back from a fantastic SfG Annual Meeting 2024 in Amelia Island, FLA! ☀️🌴 We very excited to join the party here on bluesky and to continue the dissemination of knowledge and the promotion of glycoscience worldwide! Follow us for always exciting #glycotime 👍😀

The Baker lab seems serious about moving into enzyme design. Here, they train a flow-matching model that can be conditioned by atomic coordinates and then use it to design enzymes based on active site geometry specified by density functional theory. www.biorxiv.org/content/10.1...

I am so happy to be here. What I loved about Twitter was learning about new science and scientific insights from the people doing it. It’s great to have a place where those conversations can take place (and be found). 🧪

Cool work using bioorthogonal click chemistry to measure the stability of PD-L1 in complex with a therapeutic Affibody! Led by Dr. Rafael Bernardi at Auburn and Dr. Michael Nash at the University of Basel pubs.acs.org/doi/10.1021/...

Carolyn Bertozzi is here too 🥳 She was amazing on the podcast, talking about how when a field is just being born, its new members may have a difficult time finding positions, as they’re not experts in any traditional field. nightscience.buzzsprout.com/1744020/epis... @carolynbertozzi.bsky.social

Now online as an accepted article, a novel hypervalent iodine reagent that functions as a source of electrophilic "N". My first student, Patrick Kelly's swan song (now a postdoc with the Stahl lab), done in collaboration with scientists at GSK. onlinelibrary.wiley.com/doi/10.1002/...

Hello science lovers on blue sky!