My goal to read more for pleasure this year is going well, largely thanks to scifi/fantasy/YA page-turners, but sometimes (okay okay rarely) I read non-fiction too www.goodreads.com/book/show/41...

Looking to master Skyline but lack time? Skyline Online returns! Join our accelerated Small Molecule course Oct 8-10, 9am-5pm EST, covering comprehensive Skyline applications in metabolomics, lipidomics, and beyond for MS data from any major vendor. Just $175 USD to go from intro to expert.

The posting is unfortunately not super clear on this, but please apply if you want to do BioML research, especially around machine learning for molecular biology and bioengineering! I get sad if there are no applicants with this profile in the pool!

Final countdown! Only 3 days to go until the YPIC Webinar #19: Transition from Academia to Start-Up. #YPIC #Proteomics #StartUpScience #ScienceCareers #AcademicToIndustry

@willfondrie.com discussing how we use AI and ML to further drug discovery here at Talus Bio. Come check it out to learn more! #regulomesummit

Epigenetics panel moderated by @lindsaykpino.com ongoing now!

Proteomics Webinar: DIA with FragPipe, DIA-NN, and Skyline Presenters: Eduard Sabidó and Brendan MacLean When: Tuesday, September 16, 8am (Pacific Time) Register Now ... skyline.ms/project/home... #massspec #proteomics

Regulome summit opening remarks are kicking off now! Lots more to come today, come check it out!

Regulome Summit kicks off in 20 minutes! We have food, coffee, marmots, posters, and lots of great content coming up. Stop by Dempsey Hall on UW campus to learn about gene regulation, nuclear proteomics, and AI-driven drug discovery!

@lindsaykpino.com talking about the power of using proteomics to measure the regulome of live cells using our platform here at Talus Bio, and how far we have been able to scale this platform up to further cancer drug discovery and more. #regulomesummit

ELIXIR-NL's @magnuspalmblad.bsky.social co-organized the Computational Proteomics Dagstuhl Seminar 2025, uniting experts in ML/AI for proteomics. Breakouts sparked collaborations, manuscripts, and proposals, making this the most productive seminar yet. #Proteomics #Dagstuhl #Collaboration

Do you or your lab use the Skyline software for small molecule MS data analysis? I'm looking for people to share their applications of Skyline, to help with this year's Skyline Online, a virtual workshop/crash-course for all things Skyline! Trainees/ECR particularly welcome! Please DM! #teammassspec

Do you or your lab use the Skyline software for #MassSpectrometry #proteomics? I'm looking for instructors to help with this year's Skyline Online, a virtual workshop/crash-course for all things Skyline! I'm especially looking for early career researchers for this opportunity. Please DM!

Wow, talk about Baader-Meinhof phenomenon -- I just submitted a grant a few hours ago on MNP. @benneely.com small world lol

These findings provide new insight into blood aging at the source, and raise the possibility of targeting inflammatory HSCs to "rejuvenate" blood production in aging 🧪 Thanks Ksenia Safina and collaborators @trowbridgelab.bsky.social @bloodgenes.bsky.social Read more at doi.org/10.1101/2025... 5/5🏁

8 Resources to study Transcription factor binding, enhancers and histone modification distribution  1. ENCODE www.encodeproject.org/

It's time again for another panel!! What hot takes will I accidentally-on-purpose let slip in the early Pacific time hours before my brain is fully awake? How many times will I reference Kpop Dermon Hunters? Tune in for all this and more!!!!11

It made it to the ASMS proceedings for 2001! First author was Richard Johnson (at Immunex at the time) ICRAP - isotope coded reducible affinity proteomics link.springer.com/article/10.1...

Thanks to everyone that attended our #proteomics Short course last week ! We generated over 150 GB of timsTOF HT data comparing different proteomics sample Prep methods .

Chemical proteomics has brought rigor to covalent drug discovery and drugs to the clinic. Can it deliver a new generation of drug targets? nature.com/articles/s41... rdcu.be/eycCa

Nice to see our SUGA approach on PanoramaWeb. It hosts our raw files and Skyline assays, to improve data analysis reproducibility. Quick and easy N-glycomics, suitable for those trying out glycan analysis without spending extra $ on anything except PNGase-F! Paper: pubmed.ncbi.nlm.nih.gov/39978775/

Fine structural organization of the interphase nucleus in some mammalian cells, Monneron & Bernard, 1969 Gotta love these classic papers about nuclear architecture. In hindsight, all that we understand and discover today was already contained in their images. www.sciencedirect.com/science/arti...

“‘She uncovered the social experience of women in science’ — the lab assistants who never became managers, the geologists poring over data in government offices while their male peers were doing fieldwork, those who despite their advanced degrees didn’t get hired or promoted, or who were sidelined…”

Spread the word - we at @stanford-chemh.bsky.social are searching to fill a new junior faculty at the interface of molecular and computational science. See link below!

I was thinking about this in another thread, but - what *are* the details that would make a show set in a bio/chem lab “realistic”? - the pipette always needs a tip when used - some things are *scrupulously* clean, to the point that they’re worn from it - lab coats need to be dirty (or disposable)

CSH Txn meeting thread continuing here for Friday’s talks #moet2025 #moet #transcription /1

I had meant to live-post more of my Boston trip but clearly it was a whirlwind 😂 Excellent conversation with amazing company. And of course THE WHEEL made an appearance! @andreagut95.bsky.social @juliar2bs.bsky.social

Easy, The Expanse S04E08 around 29 minutes they put a sample in THE MACHINE (notice it wasn't an instrument) and it spits this out right away. Not as glamorous as other instances, but totally spot on with bonus points for UniProt IDs. (h/t to @alexhgo.bsky.social, right?)

Timmerman Traverse for Life Science Cares raises another $1.1M to fight poverty. timmermanreport.com/2025/08/timm...

This was a fun one. I never knew it was my life goal to eat pasta out of a hand-carved parmesan bowl but that's on my (parmesan-carved) bucket list now.

Just how hard can you push cells to make proteins that they don’t need to make?

Celebrating Al Burlingame's 41 years of the @asbmb.bsky.social Molecular and Cellular Proteomics meeting which he started before "proteomics" was a term. Congrats Al!

Are you a student with a great proteomics idea? The SPF can help turn it into reality. Call opens in October ! Stay tuned for details in September! #SPF #proteomics #funding #ECR

New preprint reveals why IDO1 inhibitor trials failed! Led by Peter Murray @mpibiochem.bsky.social our collaboration discovered IDO1 actually kills ovarian cancer cells via GCN2/ISR pathway - not protecting them. Spatial proteomics uncovers unexpected biology. www.biorxiv.org/content/10.1...

I'm at day 3 of @asbmb.bsky.social back "home" at the @broadinstitute.org . Crazy how much Kendall Sq has changed in the 11 years since I left Boston.

So grateful and honored to receive the MCP Lectureship Award at the #ASBMBProteomics meeting at the Broad Institute! Huge thanks to the wonderful organizers and to everyone—past and present—who’s been part of our lab.

Here’s my latest story, link is here. www.nature.com/articles/s41... with registration and here is a quasi-open access link. rdcu.be/ezCRE It builds on this one. www.nature.com/articles/s41... and this one...https://www.nature.com/articles/s41592-023-01781-7 Ok enough URLs. Let me 🧵 this.

Thrilled to share our latest work, just published in @nature.com ⬇ www.nature.com/articles/s41... We discovered that PARP inhibitors 💊 trigger histone eviction from the chromatin and this creates a hidden vulnerability in PARPi resistant tumors. 🧵 (1/8)

Thanks to both Ben @proteomicsnews.bsky.social & @benneely.com for a great chat on ProteomeXchange, HUPO-PSI, #quantms, formats, and PRIDE. I shared my personal view on open data, availability & standards. Feeling privileged to work at EMBL-EBI/PRIDE and grateful to keep learning from my colleagues.

Interested in the proteome-wide selectivity of diverse electrophiles? The proteomics data for our study on this headed by @pzanon.bsky.social are now public on @pride-ebi.bsky.social: www.ebi.ac.uk/pride/archiv... Full story: chemrxiv.org/engage/chemr... #ChemBio #ChemSky #ChemicalProteomics

Breaking: The Gates Foundation said it would commit $2.5 billion through 2030 to support women’s health initiatives, its largest funding commitment ever to the issue. www.statnews.com/2025/08/04/b...

Lotta familiar names on the 2025 Mid-Year Venture Healthcare Report ❤️ www.hsbcinnovationbanking.com/us/en/busine...

Excited to share a new preprint from the lab. We show that PTMs like phosphorylation & glycosylation dynamically reshape proteome-wide ligandability in cells, including proteins like KRAS. Great collaboration with the Huang Lab, @forlilab.bsky.social and BMS. www.biorxiv.org/content/10.1...

I don't get many opportunities to bake lately, but I love it! Homemade white cake cupcakes with cream cheese frosting and cookie crumble

My book Epigenetics: History, Molecules and Diseases will be published in exactly one month (September 2). Finalizing cover (looks great), probably going to printer this week. Nervous anticipation is the mood right now.

At a symposium where I'm one of the only PUI faculty and I've just been playing therapist to super kind and well-meaning R1 faculty to get them to not 👏take👏mentee👏behavior👏personally👏. 1/n

🤔... The ten dollar proteome: low-cost, deep and quantitative proteome profiling of limited sample amounts using the Orbitrap Astral and timsTOF Ultra 2 mass spectrometers www.biorxiv.org/cont... --- #proteomics #prot-preprint

There have been suggestions that conflicts of interest should be clearly displayed by speakers at all times. I've got a leak from a factory that is preparing for #ASMS2026 and they've shared their new conflict of interest outfits for the presenters. (I think @benneely.com had this idea?) Thoughts?

An inspiring paper by the group of Jacob Geri in Analytical Chemistry. They present a method for residue-specific #chemoproteomics without the need for an enrichment step. To achieve this, they developed reagents that shift the ion mobility for gas phase separation. pubs.acs.org/doi/full/10....