I finally gave Marimo a try and it's pretty cool. I definitely recommend giving it a shot if you find yourself coding #Python in Jupyter notebooks with any frequency. marimo.io Clean UI, stored as a git-friendly plain python script, with reactivity for reproducibility. 🐍

New faculty position opening at @stanford-chemh.bsky.social . Especially interested in candidates with deep expertise and vision for the future of AI/ML/computational models of biomolecules. Please RT

@lindsaykpino.com talking about the power of using proteomics to measure the regulome of live cells using our platform here at Talus Bio, and how far we have been able to scale this platform up to further cancer drug discovery and more. #regulomesummit

Regulome Summit kicks off in 20 minutes! We have food, coffee, marmots, posters, and lots of great content coming up. Stop by Dempsey Hall on UW campus to learn about gene regulation, nuclear proteomics, and AI-driven drug discovery!

@willfondrie.com discussing how we use AI and ML to further drug discovery here at Talus Bio. Come check it out to learn more! #regulomesummit

I just saw this manuscript from @lindsaykpino.com @willfondrie.com @jspaezp.bsky.social Native, Spatiotemporal Profiling of the Global Human Regulome www.biorxiv.org/content/10.1... using #quantms. It just made my day!!! So glad hours of coding are used by others. Thanks guys

PhD-based positions (beyond post-doc) are becoming scarce but these four presenters have made their own paths. Worth tuning in if you’re curious about leveraging your expertise into something other than (or in addition to) papers and grants.

It was nice to get away to Mt Rainier 🏔️ for a long weekend camping trip. We even got to see some marmots!

Definitely PhD level. No question 👏 But seriously, I thought other folks were joking 🙃

Just had an #AI agent (Gemini CLI) write data models to validate outputs of a pipeline and unit tests for the workflow. They need some work, but were pretty good. However, the best part is this was all while I was eating dinner and reading physical books with the kids. Pretty cool 😎

Even with everything going on, happy Indepenence Day to my friend in the US. Here is a version of “Battle Hymn of the Republic” that I’ve been working on. 🪕 I’ll eventually learn to sing, but today is not that day 🙃

If you're working on cool chromatin biology, gene regulation, or nuclear regulome science, I want to work with you!! Our "Early Access Program" is officially open. Everything we generate together will be open-sourced with the community. --> Apply here: forms.gle/cJqtTkRRZU5m... <-- 11/?

Check out just a piece of the cool stuff we’ve been up to! 🧬

Here we go, my first skeet-torial(?) on Bluesky for my first paper from @talusbio.bsky.social ! www.biorxiv.org/content/10.1... This preprint describes our scalable, mass spec-based method for measuring which (and how many of them) proteins are interacting with DNA. 1/?

A nap and grilling fajitas on Father’s Day. What could be better than this? 🎵 Queue the Moana 2 soundtrack 🙃

Our website @talusbio.bsky.social has a new look! 👀 talus.bio

Nothing deflates a mood faster than a flat tire with no tube or patch 😔 🚲

Remember to send out your reprints from #ASMS2025! From the home screen, select "More", then "My Reprint Requests". You can email to yourself the names and addresses of everyone who requested. Android has a bug but iPhone and the desktop work. The desktop site is: eppro01.ativ.me/web/planner....

We recently released a tool to help you with this. 🚀 Say hello to pridepy — your Python for grabbing data from the @pride-ebi.bsky.social! To search metadata or download files via FTP, Aspera, Globus, or S3, and is perfect for bioinfo workflows. Check it out 👉 github.com/PRIDE-Archiv...

Stop by poster ThP 289 to… calmly discuss… metadata collection and management with Anastasiya 👏 #ASMS2025

Stop by poster ThP 289 to… calmly discuss… metadata collection and management with Anastasiya 👏 #ASMS2025

New in DeepLC! Ability to deal with wild, weird, and wobbly LC setups or peptide modifications. This ability is possible with transfer learning; where only a minimal amount of training peptides are needed for accurate retention time predictions. www.biorxiv.org/content/10.1...

It was a lot of fun participating in the Biomarker workshop panel at #ASMS2025. Thank you to all of you who were there! Also, they got some pictures:

Come out - it’s going to be awesome! 👏 #ASMS2025

I’m at poster 510 today. Stop by and say hi! 👋

Join us Monday night for hot takes and provocative discussion! Is it possible to NOT degrade BRD4? How much desthio-biotin is too much? I guess also things like whether "standard" mass spectrometry approaches work for chemoproteomics, where warheads are headed, and how to grow the field.

That’s a wrap on our #ML for #MassSpec short course at #ASMS2025 🎉 Thanks to all of the participants who made it a joy to teach 👏

Fueling up with a cortado at Ceremony again this morning Come see my poster #ASMS2025 on Tuesday about our recommender system method for predicting the retention times od undetected peptides… called Cortado 😉 #ASMSBmoreEats

Join @lindsaykpino.com, me, and our amazing panelists for the #ASMS2025 #Chemoproteomics workshop on Monday!

☕️ ✅ #ASMS2025 #ASMSBmoreEats

Going to #ASMS2025 and curious about what we've been up to @talusbio.bsky.social? Check out our posters, talk, and workshops! Check out all of our events here 👇 talusbio.github.io/talusbio-at-... Here are the events I'll be presenting at or helping with so far. Come by and say hi! 👋 🧵 (1/6)

What, not brunch time at #ASMS2015?!? If you do find yourself needing a break, treat yourself to Spoons in Fed Hill. It’s tiny, quaint, and delicious 😋 www.spoonsbaltimore.com #ASMSBmoreEats

Paula Burton and I are super excited to host our first ever Entrepreneurship in Mass Spectrometry workshop at #ASMS2025! The goal is to give some straight talk on how ideas get from bench to boardroom, from pipettes to pitch decks.

Need another great coffee shop while at #ASMS2015? Try ceremonycoffee.com Ceremony is both delicious and has two nice locations: one that is an easy walk from the convention center and the other in Harbor East has a great view! #ASMSBmoreEats

The sad news is that my hiking boots for the last 12 years finally deteriorated. So many adventures in them! The AT, Harpers Ferry, Chincoteague, 3 ft of snow in Baltimore, MN trails, Rainier, all kinds of trails in WA… You will be missed 🫡

First camping trip of the season done and dusted 🏕️ It was great to disconnect for a few days and I’m looking forward to the others we have planned this summer!

@lindsaykpino.com’s push for rigor and evidence is one of the things that drew me to @talusbio.bsky.social 👏 This has held up well over the last few years since I wrote it: willfondrie.com/2021/09/why-...

Casanovo continues to be a fun project to be a part of 👏

You’ll definitely need some great coffee to fuel up while at #ASMS2025 ☕️ One of my favorites is only a short jot away! Who knows - maybe their baristas will swing by in their mobile espresso bar… a Mini Cooper Check out Vagrant Coffee: www.vagrantcoffee.com #ASMSBmoreEats

🚧 Refactored lesSDRF; feedback welcome! I’ve pushed a new version of lesSDRF to make high-throughput SDRF annotation faster and more intuitive. Github issue: github.com/CompOmics/le... Temporary app: refactorlessdrf.streamlit.app I could use some feedback before making this the new lesSDRF 🙏

Who doesn’t love breakfast food? If you’re at #ASMS2025 and craving Cap’n Crunch French toast - and you should - look no farther than Blue Moon Cafe 🌙 Bonus: open 24hrs on weekends and the fed hill location is walkable from the conference. bluemoonbaltimore.com #ASMSBmoreEats

Going to #ASMS2025 and need some delicious tacos 🌮? Or maybe you need to unwind with a great margarita or house sour? Check out Clavel. Definitely a car ride from the convention center, but it won't disappoint: barclavel.com #ASMSBmoreEats

Free in-person registration is open for #MLCB2025! Sept 10-11 at @nygenome.org and online at youtube.com/@mlcbconf. Paper/abstract deadline is June 1, more deets including our fantastic invited speaker lineup at mlcb.org! Please RP.

Quote skeet with a picture of the airplane you'll accept as a bribe

First up is a old favorite for my wife and I. We used to live a few blocks away and this was one of our favorite date night spots. Great house-brewed beer? 🍻 ✅ Rosemary-garlic fries? ✅ Delicious pub food? ✅ The Brewer's Art is worth the trek. www.thebrewersart.com #ASMSBmoreEats

Going to #ASMS2025 in Baltimore this year? I did my PhD in Bmore and I’ll be sharing my favorite food and coffee spots (if they still exist 🙃) 👀 #ASMSBmoreEats if you don’t want to miss anything!

Over the last couple weeks, I've had the opportunity to guest lecture in 2 courses at UW! Huge thanks to @dschweppe.bsky.social and Dean Petit for inviting me to share my passion for #ML / #AI in bio with your students. It's fun to (hopefully) inspire the next wave of talented folks! 🧬🤖💻

Attending #ASMS2025 in Baltimore? Interested in quantitative proteomics? Join us Sunday Afternoon, June 1st for our annual Skyline User Group Meeting. We have a fantastic group of speakers. For information and to Register: skyline.ms/project/home... #massspectrometry #proteomics #metabolomics

May Institute on Computation and Statistics for Mass Spectrometry and Proteomics is off to a strong start with a discussion of quantitative proteomics with Skyline. I am grateful to the incredible team of instructors @lindsaykpino.com Susan Abbatiello and Brendan MacLean for making this happen

AI in proteomics starts in 7 minutes! We're here! us-hupo.org/Webinars -w00000hoooo!