Mitochondria Are More Than Powerhouses—They’re the Motherboard of the Cell great work by Martin Picard www.scientificamerican.com/article/why-...

Wow, incredibly promising preliminary data on real world use of RSV vaccinations.

Great story from @jonelaleccia.bsky,social apnews.com/article/zepb...

1/10 Today in @science.org in collaboration with the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...

Some cover art I made for a great paper about the body’s clock and biological aging! #SciArt

✊ Dundee Uni backs down from plans to cut 700 jobs after pressure from unions and the community. Now they must take compulsory redundancies off the table. Solidarity works.

Paradoxically, both GIPR agonism and antagonism potentiate weight loss when paired with GLP-1R agonism. Two new studies in @natmetabolism.nature.com decode the different neural mechanisms employed by each strategy. Check out the #News&Views by @adriaenssenslab.bsky.social here.

The UK government is promoting a “strategic shift” from “treatment to prevention.” Healthcare alone cannot restrain demand and prevention requires action on wider determinants of health, say Vageesh Jain and Thomas Beaney www.bmj.com/content/389/...

So depressing...

#Hiring soon for a research assistant with a BSc in #pharmacology, #physiology or #biochemistry. Looking for someone young and eager to learn, pre-PhD. Job advert will go live in a few weeks #newPI #Sheffield #neuroscience #brainbloodflow #CBF #science

I write about marimo, and how to choose the right programming language for your research, today in @nature.com www.nature.com/articles/d41...

Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2 https://www.biorxiv.org/content/10.1101/2025.04.19.649664v1

179 experts. 28 countries. 1 message: Long COVID is real, multi-systemic, and devastating. It affects over 400 million people. And we're not prepared. New global consensus just dropped. link.springer.com/content/pdf/10… 🧵

Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell! We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals! www.sciencedirect.com/science/arti...

www.nature.com/articles/s42... Metabolites are not genes. repeat, please!

Cells are swapping their mitochondria. What does this mean for our health? www.nature.com/articles/d41...

It used to be thought that T-cell priming occurred as single phase. Now we know it takes two. www.science.org/doi/10.1126/... @science.org

Scientists have created the first map of mitochondria throughout the entire brain https://go.nature.com/4c8CLNM

Check out this new podcast by my friend @anideshpande.bsky.social! It aims to delve into the history of groundbreaking discoveries in life, science and medicine. The first episode is a fascinating journey through our understanding of diabetes. I looking forward to future episodes!

Asymmetric phosphoinositide lipid bilayers generated by spontaneous lipid insertion https://www.biorxiv.org/content/10.1101/2025.03.26.645509v1

Axolotls in your timeline!

Neutrophil progenitor cell therapy rescues host defense against Staphylococcus aureus in murine chronic granulomatous disease https://www.biorxiv.org/content/10.1101/2025.03.26.645550v1

Macrophage ferroptosis inhibits Aspergillus conidial killing in lung transplantation https://www.biorxiv.org/content/10.1101/2025.03.13.643092v1

Interesting!

A truly depressing article in #Nature listing of all the damage done to #science in the US by the Trump administration in just one month 💔 for so many friends and colleagues there #solidarityforscience 🧪 www.nature.com/articles/d41...

Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow. www.biorxiv.org/content/10.1...

Elovl1-depleted T cells gain increased fitness and synergize with anti-PD-1 therapy to enhance antitumour responses @nature.com

Cyclic metabolic switching theory www.nature.com/articles/s42...

www.nature.com/articles/s41... @halloulab.bsky.social

Our Brunel University members are out in force on the picket line today. Fighting back against plans to axe one in five jobs while the vice-chancellor awards himself an 8% pay rise. Send them your solidarity ✊

A new spinout to transform fibrosis treatments has launched Forth Therapeutics (Forth Tx), a new spinout led by IRR's Neil Henderson, aims to develop targeted interventions to halt and potentially reverse the course of fibrotic disease. 📰Read the full article here: edin.ac/4iyNgvX

This message needs to be heard widely.

A protein involved in Alzheimer’s disease progression has been linked to normal brain ageing, raising the prospect that researchers could target it to stave off age-related mental decline https://go.nature.com/3XqSge8

Are you an undergraduate student looking to gain hands-on experience in a cutting-edge research environment? 6-8-week paid opportunity to work alongside Research Technical Professionals (RTPs): itss.org.uk/tsn/tsn-roks...

If you've not considered joining a union yet, now is a good time... @ucu.org.uk

It's International Day of Women and Girls in Science and we asked Research Technician Anna Popravko to share her career journey and experience of being a woman in the field. Read Anna's full story on IRR Stories: edin.ac/3CGMZrD #February11

New Paper! Research from the Fidanza Lab at the Centre for Regenerative Medicine has identified a new molecule to improve blood cell production in the laboratory 🩸Read here: regeneration-repair.ed.ac.uk/research-identifies-new-molecule-to-improve-blood-cell-production-in-the-laboratory

Read the full Nature paper: www.nature.com/articles/s41...

Delighted to have been awarded an International Joint Project grant from @royalsoced.bsky.social This will fund 12 exchange visits between @edinuni-irr.bsky.social and @uni_muenster over the next 2 years. 👉 tinyurl.com/5n7fkvwa. Looking forward to enhancing 🏴󠁧󠁢󠁳󠁣󠁴󠁿 🇩🇪 collaborations @EdinUni_CRH 🕺💃

It's #HPVAwarenessDay and we're answering common questions about HPV and the vaccine. Want to find out more? Visit www.askaboutHPV.org #OneLessWorry

This is Ralph. His body composition is approximately 40% ear. But that does not mean he wants to listen to your podcast. 12/10 (IG: ralph_kd0821)

First Post on blue-sky. We are hiring! Post-doctoral position available in the neuroimmunology of stroke. Please check out link below and share elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

This is a rough day. But I'm also reminded of the fantastic people I work with in the #harleylab Journal of Advanced Age indeed 🤣

I'm delighted to share a new story from our lab published today at @cp-cellmetabolism.bsky.social! In it, we describe how cellular therapies for cancer can be metabolically and epigenetically enhanced by redirecting how glucose is utilized during in vitro expansion. 1/ www.cell.com/cell-metabol...

Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice www.science.org/doi/10.1126/...

Delighted to share our paper on adipose gd T cells making IL-17 every night for homeostasis, coordinating lipid metabolism after eating @natureportfolio.bsky.social Huge effort by whole team and collaborators to work this out. www.nature.com/articles/s41...