Tumor-derived CD13 helps cancer cells colonize the brain 🧠🧪🔬 Led by @lbejarano.bsky.social w/ many wonderful collaborators in @joycelab.bsky.social and in Lausanne 🙌 @cp-cellreports.bsky.social @fbm-unil.bsky.social @unil.bsky.social @ludwigcancer.bsky.social Article: www.cell.com/cell-reports...

A big thank you to @embo.org for supporting our lab, we’re equally honoured and thrilled to be part of the EMBO family! 🤩🤩🤩 The IG grant will allow us to continue building our research program on immuno-oncology and hopefully contribute to improving care for patients with brain cancer 🧫🔬

Yet another great reason to live in Europe!! Multilingualism protects against accelerated aging 😀 An analysis of aging in >86,000 participants across 27 European countries Amoruso et al, Nature Aging 🧪⏳ www.nature.com/articles/s43...

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗 beta.ideas.lego.com/product-idea...

Super interesting, congrats Cristian and co-authors! 🤩

So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration! dx.doi.org/10.1111/imr.70063

A team led by Ludwig Lausanne’s @johannajoyce.bsky.social & former postdoc @alvarezprado.bsky.social reports a potential drug target whose loss in certain GBM cells triggers antiviral alarms to stall cell proliferation & makes GBM tumors in mice more amenable to anti-cancer immunity. bit.ly/4nhZ7Bj

Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."

I’m beyond thrilled to announce that we’ve been awarded the ERC Starting Grant! 🥳🥳🥳 This exceptional support will let us look into how ageing and genetic variation shape responses to therapy against brain metastatic tumors 🧠 Let’s go! 🤩 #ERCStG #Ageing #Immunogenomics #BrainMetastasis

How can we reawaken the body’s own anti-viral defenses to fight brain cancer? Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏 #BrainTIME 🧠🦠🧪 🧵 www.sciencedirect.com/science/arti...

Can we exploit anti-viral immunity to treat brain cancer? 🦠 🧠 Our last results suggest so, go ahead and check the paper if you’re curious! 🤓 www.cell.com/cell-reports... #Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1

Great technique from my @crick.ac.uk colleagues in @petrznam.bsky.social lab Reconstructing neural circuits with barcoded Rabies virus & in situ sequencing www.biorxiv.org/content/10.1...

What a wonderful week we’ve had here together in Lisbon for #EACR2025! Thank you to everyone who attended, presented at and helped organise this fantastic event. Sign up here for updates about EACR 2026 in Budapest… 👀 eacr.us5.list-manage.com/subscribe?u=...

Good to have some measurable readouts supporting something which was already obvious… #mass_surveillance #AI #computer-vision

90% of doing science is being open to new ideas.

Yet another reason to rethink the current publication system towards an alternative which prioritises publishing reliable science over profit, protects scientists and their research and values the work we all do to communicate new knowledge. We can, but do we want to? www.nature.com/articles/d41...

Excited to see our image on the cover of #Immunity today 🤩 Congrats to the amazing @lbejarano.bsky.social & all authors for our #brain #tumor #vasculature study www.cell.com/immunity/ful... Huge 🙏 🙏 to the v talented @joanagcc.bsky.social for creating this super cover 🧠🧪 @cp-immunity.bsky.social

@contracancerinv.bsky.social: GRACIASx27000 (récord de registro en la XII Carrera hoy en Madrid), aunque ese número debería de multiplicarse por muchísimos miles más, por la cantidad innumerable de personas con cáncer y de investigadores/as que se benefician de vuestro apoyo. Un abrazo muy fuerte! 💙

Nice run through the beautiful forest of Strassen to contribute to the non-stop 24h race of the LIH team for #Relais2025Lux Together against #cancer, let’s go team!! 🔥

How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪 Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻 🧵 @cp-immunity.bsky.social www.cell.com/immunity/ful...

Extraordinary resource for the #brain_cancer community from @johannajoyce.bsky.social lab, led by the equally extraordinary @lbejarano.bsky.social, so happy to see this out! 👏 👏 👏

This wouldn’t have been possible without the support of the @braintumourcharity.bsky.social, they’re doing a fantastic job helping not only us scientists, but also patients and families ❤️ Thank you! 🙏

It is disappointing that we still need to fight against social exclusion and discrimination, it is discouraging to witness abusive governments attempt to shut down critical thinking, but we will stand together for human dignity, freedom and knowledge as a vehicle to protect these. Please sign ⬇️

Excited to share a new paper from our lab 😀 We investigate the tumor microenvironment - to reveal factors influencing cancer progression & therapy response 🔬🧪 So we naturally wanted to ask - does the gut #microbiome influence brain #metastasis 🦠 🧠? Massara et al 2025 www.cell.com/iscience/ful...

Professor @charlesswanton.bsky.social will be opening the #EACR2025 Annual Congress with his Keynote Talk: 'Myeloid Mayhem: Inflammation driven lung cancer initiation and progression' Explore the impressive scientific programme: 2025.eacr.org/programme

Today is #WorldCancerDay Did you know❓ Vaccination against #hepatitisB can help prevent liver cancer in children, while #HPV vaccination for young girls can reduce the risk of #CervicalCancer later in life. Learn more 👉bit.ly/2NeFF8B

Today is #WorldCancerDay A day to appreciate all the clinicians & researchers 🧪 who dedicate their lives to the fight against #cancer And to also reflect on what a diagnosis of cancer means - to the person, their family, and their community Every country, together against cancer 🌍 🌎 🌎 #WCD2025

One of the great things about being a #scientist is experiencing research 🧪- and life - in different countries! Thanks to @naturecancer.bsky.social for this interview, where we talked about thriving in diverse ecosystems, supporting young cancer researchers and more! www.nature.com/articles/s43...

I couldn't be happier to welcome our new technician and first lab member, Camille Cialini, who will bring her >7 years experience working on neuropathology to the team, such a perfect match! 🤩 Very much looking forward to working with you Camille, welcome to the lab! 🎉🎉🎉 #newPI #happyPI #welcome

Come join us in the 2025 @helloeacr.bsky.social meeting in Lisbon! Amazing speakers line-up and a fantastic environment plus a 2-day showcase event for early career researchers to present their work! 🤩 Discounted registration until the 28th Apr and travel grants are available 😌 #EACR2025 #lisbon

A new #ScienceImmunology Review discusses the mechanisms through which dendritic cells influence cytotoxic CD8+ T cell responses against cancer. scim.ag/3PU7hRo

We have a wonderful program lined up for #EACR2025 in beautiful #Lisbon 🤩 All of us at #EACR are looking forward to see you in June! #cancer #research 🧪⚕️ 2025.eacr.org @helloeacr.bsky.social

🚨We're hiring! We've opened a fully-funded Ph.D. position to join my lab at the #LIH, if you are interested in understanding how genetic variation influences immune responses against cancer, don't hesitate to apply! 🔬 🧪 More info below ⬇️ www.lih.lu/en/job/?valu... #cancer #immunology #genomics

Wonderful kick off of our #CANBIO2 retreat with amazing talks by Sabine Tejpar, Jorge Moscat, María T. Diaz-Meco, @jenspuschhof.bsky.social and Thomas Helleday. What a great way to start in a new institute! 🤩 #newPI #scienceisfun #cancer_biology

Disappointing new study showing - once again - that women are leaving research careers at far higher levels than men If you're interested to read about strategies to reverse these types of curves, check out our recent #Cell perspective- link below ⤵️ #WomeninSTEM 👩‍🔬👩🏾‍🔬🧪 www.nature.com/articles/d41...

An impressive new issue of Neuron on the science of brain aging with 10 papers on everything from sex differences, role of astrocytes, immune system, waste clearance, autophagy, DNA damage, and rejuvenation cell.com/issue/S0896-...

Spatial Proteomics is the Method of the Year 🧪 from Nature Methods! Resharing our #HIFI paper - which we developed to be #accessible and #economical for all interested in #spatial analysis of complex tissues @drspencerwatson.bsky.social @natureportfolio.bsky.social www.nature.com/articles/s41...

We are offering a very exciting PhD project 🤩-Project 2- in this great training program! @icrlondon.bsky.social @imperialcollegeldn.bsky.social @crukconvergence.bsky.social Please share 😊 ! Design of advanced therapeutics against metastasis👇 www.convergencesciencecentre.ac.uk/training/con...

Sub-cellular Imaging of the Entire Protein-Coding Human Transcriptome (18933-plex) on FFPE Tissue Using Spatial Molecular Imaging www.biorxiv.org/content/10.1... With clear explanation of how this amazing technology achieves RNA (ISH) probe decoding at Hamming Distance of 4

Big news for everyone working on scRNA-Seq analysis, scCustomize v3 is out!! 🥳🥳🥳 Huge thanks @samuelmarsh.bsky.social for developing and maintaining such a useful tool! 🙏

🚨Interested in understanding better the systemic consequences of cancer? Great speakers lineup, send your abstract before the 13th Jan 2025! @helloeacr.bsky.social

Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8

Amazing study by the @obenaufa.bsky.social lab, including evidence for a novel mechanism of CD8 stimulation by monocytes: MHC-I #crossdressing. Make sure to check it out! 🤩🤩🤩

Many thanks to The Scientist for covering our recent paper on fibrotic scarring and brain tumor recurrence 🙏 Here's the #openaccess link for our original paper in Cancer Cell led by Watson*, Zomer* et al: www.cell.com/cancer-cell/... #scicomm 🧪🔬 www.the-scientist.com/blocking-sca...

Our new work! We show that T cell cross-reactivity can be reduced without modifying the TCR itself (by dramatically enhancing antigen discrimination). Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors www.biorxiv.org/content/10.1...

An absolute #mustread showing how much the publishing industry is using and abusing scientists for profit. And with a bonus metric to catch fraudulent citations, the #impactinflation

i might be biased, but this place is amazing: great colleagues, vibrant campus, brilliant students/postdocs - and Vienna! perfect for starting an ambitious project. apply now for a GL position at the IMP … www.imp.ac.at/career/open-...

Interested in MAP kinases? Submit your abstract for the @helloeacr.bsky.social virtual conference 'Drugging and Regulating the MAP Kinase Pathway' before the 16th Dec! Link below 👇 eacr.org/conference/b...

Amazing resource, a big thank you to everyone who made it possible! 🙏 #newPI #funding #earlycareer