UK NK 2026 in Cardiff. January 9th. Be there. eventbrite.co.uk/e/uk-nk-confer… Hosted by Rich Stanton, Ceri Fielding & Eddie Wang

I was Chair of @biologists.bsky.social when we started this initiative, the brainwave of the @stevenkelly.bsky.social It was an imaginative idea and I am thrilled to see this landmark Remember: @biologists.bsky.social are the goodies in scientific publishing!

We can make the flexibility of a model match the hypothesis being tested -- more flexibility is not always better, if it prohibits rejection of the hypothesis. Here is one simple case involving T cells where it made a difference! www.biorxiv.org/content/10.1...

If you're a postdoc interested in starting your own group, please consider the Dunn School at Oxford, UK. It's a fantastic department and university for molecular immunology and all aspects of immune research!

Temporal control of cytokine production is lost in 2nd-gen CAR-T cells, says Patel et al. This could be key to understanding their efficacy and toxicity in cancer immunotherapy. 🧬 🔗 https://bit.ly/4lOLicw ##CancerImmunotherapy

Our new review article led by Jordan Kramer: Platforms for studying cell–cell recognition by immune cells onlinelibrary.wiley.com/doi/10.1111/...

📢 Registration is open for the Biomembrane Days 2025! 🔗 biomembrane-days-2025.mpikg.mpg.de A top-notch lineup of speakers, 120 posters, 200 scientists. 📜Submit an abstract by July 14 🏆3 Poster prizes ⚠️Limited spots-previous events were fully booked! #BiomembraneDays2025 #Biophysics #CellMembranes

CombiCells allow combinatorial display of cell surface ligands www.nature.com/articles/s41... A new Tools of the Trade article from Nature Reviews Immunology by Sofía Bustamante Eguiguren in our lab highlights the CombiCell platform to combinatorially display and titrate many cell surface ligands

The molecular reach of antibodies crucially underpins their viral neutralisation capacity Our work on measuring and understanding the role of molecular reach on antibody function is now part of a list of editor's pick manuscripts: www.nature.com/collections/...

A fantastic EACR conference that focuses on all aspects of immune responses to cancer! Barcelona - May 2025

🚨New paper alert! 🚨 Our latest work in @cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇 sciencedirect.com/science/arti...

📢 LAST CHANCE to submit your abstracts for BSI Oxford and @immunologyoxford.bsky.social's #OIS25 Symposium This is your opportunity to take part in this celebration Oxford's outstanding #immunology research 🔬 Submissions are open until midnight on Friday 7th Feb 👉 bit.ly/4elJmnG

📢 Abstract submission for BSI Oxford and @immunologyoxford.bsky.social 's #OIS25 Symposium closes NEXT WEEK (7 Feb) Don't miss your chance to take part in this celebration of the outstanding #immunology research happening across Oxford 💫 Submit your abstract here 👉 bit.ly/4elJmnG

Two weeks to go until the application deadline for ILESLA. If you or anyone you know would benefit from full funding to carry out a PhD in Life and/or Environmental Science please visit/refer to our website page iles.web.ox.ac.uk/how-apply where you can see open day videos and get full guidance.

We just can't stop recruiting! Associate professor in cell and molecular biology @dunnschool, with a preference for immunology, inflammation and/or infection - all defined broadly Come and be our colleague Deadline 28 Feb, please spread the word www.path.ox.ac.uk/vacancy/asso...

The OT-I TCR is often criticised as being very high-affinity and displaying unusual behaviour compared to other TCR transgenics. New work from @tcell.bsky.social shows this might not be the case. Will I still use OT-I and all the wonderful tools associated with it? Yes I will!

Our new work! The 3D affinities of the OT-I TCR to foreign and self-antigens predict their 2D affinities and reveal imperfect antigen discrimination www.biorxiv.org/content/10.1...

A new paper by @tcell.bsky.social and team makes important advances towards improving CAR-T technology! Read the paper here: www.biorxiv.org/content/10.1... Listen to Omer talking about the paper and his spin-out company MatchBio here: podcasts.ox.ac.uk/series/immun...

Our new work on optimising CAR-T cell sensitivity is now on bioRxiv! Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes biorxiv.org/cgi/content/...

🧵 My former office mate and esteemed colleague Anna Huhn has co-authored a groundbreaking study in @naturecomms.bsky.social. 🦠 We're talking viruses and antibodies! 1/5

Our work led by Anna Huhn is now published! The molecular reach of antibodies crucially underpins their viral neutralisation capacity lnkd.in/epe8YZPm Thank you to the reviewers for constructive feedback!

The molecular reach of antibodies crucially underpins their viral neutralization capacity www.nature.com/articles/s41... @naturecomms.bsky.social @tcell.bsky.social

Pre-print time! This time our lab tackled the enigmatic "autoinflammation of unknown origin". This is a cluster of rare patients with #autoinflammatory disease, which don't fit the criteria of other syndromes. It's not even clear its a single #disease, to be honest www.biorxiv.org/content/10.1...

Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪 go.bsky.app/PY5tCas go.bsky.app/FmERUoD go.bsky.app/6aT6qDS go.bsky.app/QSEPDoj

📢 Only few more days left to submit an abstract for #INTERPHACE2025 at @thecrick.bsky.social or get an early-bird ticket! - deadline 13th Dec! Don't miss out on presenting your work in an interdisciplinary environment, network, or maybe even find new collaborators? tinyurl.com/5n94xcuw

The danger theory of immunity strikes back... rdcu.be/d1uQN

Our new work! We show that T cell cross-reactivity can be reduced without modifying the TCR itself (by dramatically enhancing antigen discrimination). Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors www.biorxiv.org/content/10.1...

Our new work! Regulation of temporal cytokine production by co-stimulation receptors in TCR-T cells is lost in CAR-T cells biorxiv.org/content/10.1... X Thread: x.com/Dushek/statu...

Now this will be an interesting meeting... Pseudoenzymes are under-appreciated – but widespread and important meetings.embo.org/event/24-pse...

The key reagents from our recent CombiCell manuscript are now available on @addgene.bsky.social www.addgene.org/Omer_Dushek/ @embojournal www.embopress.org/doi/full/10....

We are thrilled to wake up to the news that Prof Liz Robertson CBE has been recognised in the New Year's Honours list She is now a Commander of the Order of the British Empire! Liz is a pioneer of mouse developmental genetics as well as an outstanding supporter of young scientists

Our new work is now published in EMBO Journal! We describe a method for combinatorial display and titration of ligands directly on the surface of cells. We use it to study T-cell antigen sensitivity and the contribution of co-stimulation/inhibition receptors. www.embopress.org/doi/full/10....

Hi 🇺🇸 Bluesky! Hope you had a great holiday. While you were giving thanks and eating, Oxford's Dunn School of Pathology decided it was time to set up here. Give us a follow for cutting edge biology underlying human disease, biomedical careers, research culture, students... www.path.ox.ac.uk

Canada to join Horizon Europe www.ctvnews.ca/canada/trude...

The Dunn School at University of Oxford just can't stop recruiting! This time an Associate Prof in cell/mol biology with focus on infection, immunology, inflammation Come and join us... Please spread the word www.path.ox.ac.uk/vacancy/asso...