Integrating polygenic signals and single-cell multiomics identifies cell-type-specific regulomes critical for immune- and aging-related diseases @nataging.nature.com www.nature.com/articles/s43...

Aiolos restricts generation of antigen-inexperienced, virtual memory CD8+ T cells in mice by repressing Eomes & CD122 expression @natcomms.nature.com @osuwexmed.bsky.social www.nature.com/articles/s41...

Truly the best crew. Grateful for and proud of everything we’ve done together. Here’s to the next five years! 🥂🎄🎅🏽

Registration is now open for @keystonesymposia.bsky.social "Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection." Deadline for scholarships and abstract selected short talks is Jan 7! Join us this May for an amazing meeting! keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26

A new #ScienceSignaling study reveals how salivary glands respond and regenerate after they are damaged by radiation from either proton or photon therapy, which could guide future efforts to promote salivary gland recovery. https://scim.ag/4oMc8DU

Feeling truly energized after an amazing scientific exchange. Grateful for the connections and insights. Can’t wait to come back to the next edition. @amersocvirology.bsky.social folks, this is definitely one to keep on your radar!

The Colombian and Latin American Symposium in Virology has started. Stoked to spend the next three days learning more about the region’s important contributions to the field.

The BWF New Awardee meeting has been so inspirational. The stories and passion shared are a powerful reminder of the impact we can all make in science. Super stoked to be part of this awesome PATH cohort!

Celebrating Brutus’ birthday with the lab and breaking a World Record. #Buckeyesbelong

Excited to announce that we have a new faculty search opening in the Department of Microbiology and Immunology at the University of Minnesota for a tenure track Assistant Professor in RNA Virology. More info can be found here: hr.myu.umn.edu/jobs/ext/365...

Idorn, Paludan et al. @au.dk characterize a mouse strain harboring a mutation found in a herpes simplex encephalitis patient. Defective IFN-driven antiviral responses led to hyperactivation of #inflammation, contributing to disease development. rupress.org/jem/article/... @civia-aarhus.bsky.social

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

We are currently in the process of recruiting a technician. 🥼🐭🔬 If you know anyone with enthusiasm to learn new skills and stamina to hear me go on and on about IFNs, please have them reach out to me for more details!

Midwest Virology Symposium was amazing. Strong Ohio representation from friends at OSU and Cleveland Clinic 📸. Huge thanks to colleagues at the University of Kentucky for being generous hosts and putting together a fantastic program to showcase our trainees’ work. #MidwestVirology #MVS

Hey friends, it’s Ride Day! I’m pedaling with purpose for Pelotonia to end cancer. Every mile counts and so does your support. 🚴🏼‍♂️ #onegoal www.pelotonia.org/profile/AF74...

10 years ago, SCOTUS made a landmark decision to extend marriage rights and allowed me to finally say yes to a life together with a wonderful human evening. She rocks my world! #anniversary

We wrote a review on the free nucleotide pool as a central playground in human, bacterial, and plant immunity – now out in Nature Reviews in Immunology www.nature.com/articles/s41... Was fun to write this piece with Dina Hochhauser! Here is a thread to explain the premises 1/

Callers to 988 used to be able to press 3 to reach counselors specially trained to help LGBTQ+ young people. The service had been reaching 70,000 people a month.

On our way to Montreal for #ASV2025. Make sure to come check out Matt’s (@mattmcfa17.bsky.social) work during W22-6. Can’t wait to see you all! @amersocvirology.bsky.social

One of Ohio’s finest sons. Thank you for your service and contributions to the field!

The reading list keeps growing!!!

📄🧫🔬🐭What are you reading this weekend? Check out @catmphelps.bsky.social, @meisellab.bsky.social, et al’s brand new work! #H2P

Please apply!

So pleased to see @mcsinton.bsky.social listed as part of the #IUIS #Risingstar2025 program! Looking forward to this event in August. iuis.org/news/meet-th...

Real Kings value higher learning. Charles IV, Holy Roman Emperor and King of Bohemia, founded Univerzita Karlova in Prague in 1348. This is the alma mater of many great minds including physiologist Jan Purkyně (Purkinje). His microscope is on display at the National Museum in Prague.

From UGA Research News - Kurup wins prestigious PATH award for groundbreaking malaria research research.uga.edu/news/kurup-w... #bwfpath

Now open - LOIs for the Investigators in the Pathogenesis of Infectious Disease (PATH) program. Deadline is July 17 @ 3pm ET. More information here: buff.ly/iSu3v60 #bwfpath #GrantOpportunity

Proposed cuts to NIH funding threaten American biomedical research, public health, and economic stability. AAI stands in strong opposition and highlights the vital role of NIH in job creation, economic activity, and safeguarding lives. 🔗 ow.ly/ww5h50W2zEs

Now in #Science #Immunology: Philips, O'Shea, &al. made mice w human pathogenic #STAT1 activating mutation. Mice had #IFNg -dependent #autoimmunity, but their innatelike lymphocytes produced suboptimal IFNg during viral infection. Exogenous IFNg🚫virus-induced lethality, suggesting possible therapy!

From Nature Communications - Aneuploidy confers a unique transcriptional and phenotypic profile to Candida albicans www.nature.com/articles/s41... #bwfpath

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

Deeply grateful to be selected for this honor! Huge thanks to the BWF for continuing to support early-career scientists, my colleagues at @osuwexmed.bsky.social, and Forero Lab trainees who laid the groundwork for the path ahead. #TeamMII

TRIMmunity!

A massive loss to the virology community. Ann was an amazing scientist and mentor, whose service to UW and the virology community in general will be sorely missed. www.cressfuneralservice.com/obituaries/a...

Yay!!

Congrats to Omkar Shinde and Pingwei Li for resolving the cryo-EM structures of free and cGAMP-bound ABCC1. This paper follows on the great work from Dan Stetson's lab revealing ABCC1 as a cGAMP exporter. www.sciencedirect.com/science/arti...

Mark your calendars Cytokines 2025 Westin Seattle! Abstract submission is opening soon. Make sure to note these important deadlines: -Abstract Submission deadline: Wednesday 18 June -Early-Bird Registration Deadline: Friday 25 July Group room rate $236 seattle.cytokinesociety.org for more details

Our work on cellular RNA interactions with MAVS that promote antiviral signaling is finally live. So grateful to our indispensable collaborators as well as reviewers who helped to strengthen our work. #RNA #innateimmunity #virology @ramlabuw.bsky.social www.science.org/doi/10.1126/...

Now online - research briefing from @inflammasomelab.bsky.social Mercedes Monteleone on our recent @natimmunol.bsky.social publication on how pyroptotic cell corpses signal to dendritic cells from beyond the grave! #inflammasomes #pyroptosis #CellDeath #CLEC9A Link: rdcu.be/d30EL

Just saw this on a quote: “We charge a 30 USD fee for for orders submitted via fax”. It made me feel old. Last time I faxed a document was in 2006.

Excited for my first bluesky post announcing TWO openings for tenure track positions in virology! I am chair of the search committee and with a new department head Mike Gale we are in an exciting building phase. Please share with anyone who might be interested: hr.myu.umn.edu/jobs/ext/365...

Jake wishes y’all a dapper Holiday season!

I’m excited to share our latest study led by @giuliapasquesi.bsky.social out today in @cellpress.bsky.social , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵 #TESky 🧪

From June '24: The transcription factor Mef2d augments type 2 immune responses during allergic lung inflammation, regulating differentiation of Th2 and ILC2 cells. https://buff.ly/3BdtFkS Work from @aydanszeto.bsky.social et al. #Immunology #ILC2s @science.org

SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusion Alex Compton and colleagues www.embopress.org/doi/full/10....

Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2 www.science.org/doi/10.1126/... @sciimmunology.bsky.social @mayerbarber.bsky.social

Poll time: Do we look like Arthur or Minions? #dressforthejob @miqdadd.bsky.social @mattmcfa17.bsky.social

Life isn’t fair! When you are hairy as a 🥝 you must endure your parents’ attempts at protect you from grotesque temperatures.

I am grateful for colleagues who are genuinely caring and kind, beyond being scientifically curious and driven. The MII family at @osuwexmed.bsky.social is where it’s at! #grateful #rideordie #MIIProud