Shoutout to our listeners for proving you can love #Tcells, Taylor Swift, and #tuberculosis epidemiology all at once. Long live The Tortured Immunologists Department. 🤍 #SpotifyWrapped

The latest issue of #Science #Immunology is out now! This week: • evaluating large language models ( #LLMs ) / #AI as potential #systems #vaccinology tools • de novo #thymus #regeneration in the #axolotl! New content every week!!!

My latest 'pinch yourself' moment from the Lab. We previewed two really really exciting papers from the Eisenbarth and Pabst Labs for @cp-immunity.bsky.social Read our summary here> www.cell.com/immunity/ful... A big well done to Gaby Berman in my group and authors of both excellent manuscripts!

Present your #immunology research among the world's leading immunologists! Submit your abstracts today for #IMMUNOLOGY2026™. Upon submission, apply for an AAI Travel Award to assist with travel expenses to Boston, MA. ✈️ https://bit.ly/48cjOtl @aai.org#immunology

Recent work in @jci.org shows that subcutaneous white adipose tissue dysfunction triggers aging-like intestinal dysfunction in mouse models. Read the article: https://bit.ly/4rBatTB Listen to the discussion: https://bit.ly/4pJvw4u

A purr-fect place to record! 😻 @brendaraud.bsky.social is not the only one enjoying her soundproof setup. 😉

Feel better during the day than at night during #influenza? Find out the “Role of IL-10 signaling in the #circadian control of host response to influenza infection” www.mucosalimmunology.org/article/S193...

#Myeloid cells 🤝 #Lymphoid cells! Michelle von Locquenghien, Drs. Pascale Zwicky, Ken Xie, and Dr. Ido Amit's lab developed myeloid-targeted immunocytokines and NK/T cell enhancers that could potentially treat solid cancers. 📃@cp-cell.bsky.social#Myeloid#Lymphoid https://bit.ly/3Mkw3eM 🎧 - https://bit.ly/4pJvw4u

Sofía Ibáñez-Molero, Dr. Johanna Veldman, and a team in the @peeperlab.bsky.social at @nkinl.bsky.social isolated #Tcell clusters with high tumor-killing potential from patients with melanoma. Nature Portfolio paper - https://go.nature.com/4i7DjXv Episode - https://bit.ly/4pJvw4u

@aai.org invites you to submit abstracts of unpublished, original research for presentation at #IMMUNOLOGY2026™. This dynamic opportunity to showcase your research empowers you to connect, collaborate, advance your career, and access cutting-edge research. Submit & save today! https://bit.ly/48cjOtl

🫀New in #Circulation: Dr. Robert Schwab and a team in Dr. Avery Posey's lab engineered CAR Tregs that treat atherosclerotic plaques in mice. Article: https://bit.ly/3MdrZ01 Discussion: https://bit.ly/4pJvw4u #Atherosclerosis #HeartDisease

🔔 New episode alert! Dr. Ana Anderson from Harvard Medical School talks about her work on #ImmuneRegulation in cancer. ▶️ https://bit.ly/4pJvw4u

Coming soon! @aai.org's second round of regular abstract submissions opens Dec 2-16. Prepare your original, unpublished research for submission today. Travel awards will also be available for submissions made during this period. https://bit.ly/3Mkn5yd #IMMUNOLOGY2026

Join us next week for an episode with Dr. Ana Anderson from Harvard Medical School! Her research focuses on understanding the pathways and mechanisms that regulate the #AntiTumor immune response.

🥜 This week: #immunotherapy for #PeanutAllergy! A team at Stanford studied the mechanisms of oral immunotherapy-induced CD4+ T cell tolerance. 🖇️ - https://go.nature.com/4nBMSyP 🎧 - https://bit.ly/3JL4pXI

This week on the podcast: What causes long-term allergies? Dr. Zhoujie Ding and a team in Dr. Marcus Robinson's group at @monashbiol.bsky.social examined the lifespan of IgE antibody-secreting cells. @cp-immunity.bsky.social paper - https://bit.ly/48o4kT4 Episode - https://bit.ly/3X0SWpZ

New review out! 😊 20 years after it’s discovery, with @iannaconelab.bsky.social we decided to bring together what we currently know about this cytokine and how it shapes CD8 T cell responses. A small contribution to make sense of a field that is moving fast 🌈 @cp-trendsimmuno.bsky.social

There's a new episode out now! Dr. @georgearobinson.bsky.social from @ucl.ac.uk talks about his research on #lupus and #SexDifferences in autoimmunity. 📍 https://bit.ly/3JL4pXI

We have a new episode out! Dr. @camilahcoelho.bsky.social from Icahn School of Medicine talks about her lab’s work on mpox and other emerging viruses, her approach to #mentorship, and how her MBA education helps her in science. Listen now: bit.ly/43M7r4x

This week: A group led by Drs. Masayuki Amagai, Hayato Takahashi, and Miho Mukai converted conventional effector T cells into functional and stable Tregs. Read the paper: https://bit.ly/4qKYimH Catch the discussion on our latest episode: https://bit.ly/43M7r4x

📢 Laine Goudy, Dr. Luke Gilbert's lab, and their collaborators recently developed a new #epigenetic editing platform that safely reprograms multiple genes in human T cells. 📃 https://go.nature.com/3JQdKNL 🗨️ https://bit.ly/43M7r4x

Our next episode features Dr. Camila Coelho ( @camilahcoelho.bsky.social ) from Icahn School of Medicine at Mount Sinai! Tune in tomorrow to learn about her work on emerging viruses. 🦠

📢 New in @nature.com! Work led by Dr. Zihai Li at the Pelotonia Institute for Immuno-Oncology have shown that #ProteotoxicStress, induced by protein aggregation, is not merely a consequence, but a driver, of the exhausted T cell state. 📄: https://go.nature.com/47zVDog 🎧: https://bit.ly/3LlRCeo

New work from the lab of Dr. Wan-Lin Lo at @utah.edu demonstrates that age-dependent Zap70 expression regulates negative selection and thymic #Treg cell development. Study🗒️: https://go.nature.com/4o9oqWn Episode 🔊: https://bit.ly/3LlRCeo

Congrats to Drs. Mary Brunkow and Fred Ramsdell on receiving the #NobelPrize in Physiology or Medicine! 🏆 We discuss their early work identifying #FOXP3 as a master regulator of regulatory T cells. 🎧 https://bit.ly/3LlRCeo

In this week's episode, we review the seminal study from Dr. Sakaguchi that led to his recent #NobelPrize! It shows that a population of T cells expressing the IL-2 receptor α chain acts to maintain self-tolerance by suppressing other T cells. 📃: https://bit.ly/49f551F 🎧: https://bit.ly/3LlRCeo

🎤 Our next episode it out! We chat with Professor Matteo Iannacone ( @iannaconelab.bsky.social ) from @@unisr.bsky.socialabout his work understanding the generation of dysfunctional adaptive immune cells in chronic #HepatitisBVirus infection. 🎧 Listen now: https://bit.ly/4o2W8xa

Dr. Heather Parsons has been awarded the Maudslien Endowed Chair in Breast Cancer Precision Oncology Research. Dr. Parsons’ research at @fredhutch.org focuses on a type of cancer marker called circulating tumor DNA (#ctDNA) that can be detected in human blood. 🎈 Congrats! https://bit.ly/3LlEpST

Online now: ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell death

Bat sarbecovirus WIV1-CoV bears an adaptive mutation that alters spike dynamics and enhances ACE2 binding journals.plos.org/plospathogen...

Deletion of the X-escapee gene Kdm6a in microglia reverses the disease-associated microglial translatome and has protective effects in female mice www.science.org/doi/10.1126/...

Quantification of timelapse 3D tumor spheroid killing activity of NK cells using a live-cell imaging system @plosone.org journals.plos.org/plosone/arti...

What is the relationship between food allergies and #AtopicDermatitis? We cover a @cp-immunity.bsky.social#AtopicDermatitispaper from Boston Children's Hospital that explores how S. aureus skin colonization can lead to exaggerated #anaphylaxis. Check it out on our latest episode: https://bit.ly/4mXBKMr

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation www.science.org/doi/10.1126/...

🔔 New episode alert! Dr. Robin Orozco ( @robsorozco.bsky.social ) from the @universityofkansas.bsky.social joins us to chat about her work on allelic variation and immune responses. Stream it here or on any podcast app: https://bit.ly/46Jf7GI

Want to see immune cells in 3D? We’ve published a protocol for 5-plex 3D imaging of whole lymph nodes, revealing germinal centers at single-cell resolution. So many possibilities ahead! Congratulations Victoire Boulat! tinyurl.com/y9ekha8c #Microscopy #Immunology #SpatialBiology

Our next guest is Dr. Robin Orozco ( @robsorozco.bsky.social ) from @universityofkansas.bsky.social Her research focuses on the role of allelic variations in immunity.🧬 🔔 Tune in to the episode on Tuesday!

Happy #InternationalPodcastDay! 🥳 We're celebrating by counting down our top three episodes of the year below. 👇

Dr. Dayana Rivadeneira and a team in Dr. Greg Delgoffe's lab showed that dysfunctional T cells in cancer harbor damaged #telomeres, which arise from oxidative stress. 📄 - https://bit.ly/42MrvmK 🗨️ - https://bit.ly/4mybUyr

This week: Dr. Upasana Das Adhikari and a team in Dr. Douglas Kwon's lab at the Ragon Institute of Mass General Brigham, MIT, and Harvard studied how immunometabolic defects disrupt the intestinal barrier in people with #HIV. Paper: https://bit.ly/46wC5zp Discussion: https://bit.ly/4mybUyr

🔪 "On a knife’s edge between #pathogen control and #autoimmunity!" Learn about Dr. Harikesh Wong's research on how #Tregs prevent autoimmunity during infection. @hswonglab.bsky.social#pathogen#autoimmunity#Tregs📍 https://bit.ly/4mybUyr

Extremely happy to see our work out in #ScienceImmunology. We show allergen-induced ECM remodelling occurs independently of IL-13 or IL-17 driven inflammation. Rather chitinase-like proteins drive airway ECM accumulation & inhibition of Ym1 can remarkably reverse it. www.science.org/doi/10.1126/...

Join us next week for a conversation with Dr. Harikesh Wong ( @hswonglab.bsky.social ) from the @ragoninstitute.bsky.social ! Check out his team's work on how #Tregs prevent #autoimmunity: https://bit.ly/3IuYdlL

📢 New in #Nature! Researchers led by Dr. Chris at Stanford have leveraged synthetic #CytokineReceptor engineering to successfully rewire #TCell fate decisions and amplify anti-cancer immunity. 📗: https://go.nature.com/4n6F6gQ 🔊: https://bit.ly/4mYJIWy

Researchers led by Dr. Manolis Pasparakis at the University of Cologne have shown that XBP1 and caspase-8 synergize to prevent #ColonInflammation. 📄: https://bit.ly/46bdosb 🎧: https://bit.ly/4mYJIWy

A new #Nature study from the lab of Dr. Nicolas Gaudenzio shows that offspring of stressed pregnant dams have dysregulated mast cells and skin-projecting neurons & quickly develop #eczema in response to harmless mechanical friction. 📄: https://go.nature.com/42dFCRW 🎧: https://bit.ly/4mYJIWy

Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV: Cell www.cell.com/cell/fulltex...

Scientists led by Dr. Katayoun Rezvani at @mdanderson.bsky.social have found that #NKCells become better at killing #cancer cells after removal of key gene targets identified by genome-wide CRISPR screening. 📄: https://bit.ly/4m8mV9y 🎧: https://bit.ly/4mYJIWy

We've got a new episode out for you now! We chat with Dr. Eric Vivier from Aix-Marseille Université about the importance of investing in science, the responsibility of governments and other organizations in funding research, and the role science plays in society. 🎧: https://bit.ly/4mYJIWy

Check out this special episode from #IUIS2025! We chat with delegates about their favorite research presented and their experiences in Austria. 🇦🇹 Listen now: https://bit.ly/4p3vmWh @iuis-online.bsky.social#IUIS2025