www.mountsinai.org/about/newsro... @sinaiimmuno.bsky.social

Check our new paper here! 👇🏼

Three monoclonal antibodies targeting the mpox virus protein A35 have shown strong protection against severe disease in laboratory and animal models, indicating potential for new therapeutic approaches. doi.org/g9zg4h

Human monoclonal antibodies targeting A35 protect from death caused by monkeypox virus @cellcellpress.bsky.social @carolilucas.bsky.social @vivianasimonlab.bsky.social @mschotsaert.bsky.social www.cell.com/cell/fulltex...

It starts in 10 minutes! Link below👇 isv-online.org/event/isv-au...

Exciting data from @camilahcoelho.bsky.social lab! Congratulations to the team!

New paper from the Coelho lab with a modest contribution from us:

Join us next Wednesday as we hear from the great work from the Ward lab!

4/ Structural studies revealed all 3 mAbs target a highly conserved epitope in the A35 dimer groove, shared across orthopoxviruses. This explains their breadth and potency.

7/ Together, our findings establish A35 as a critical therapeutic target for mpox and related orthopoxviruses, paving the way for next-generation antibody therapies and improved vaccines.

🚨New Paper in Cell 🧵🔎 Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox. We were very excited (and lucky!) to contribute to this collab. effort. 🦠“Human monoclonal antibodies targeting A35 protect from death caused by mpox”🦠 doi.org/10.1016/j.cell.2025.08.004

🚨 New article! Our study "Human monoclonal antibodies protect against death caused by mpox" is now published: 👉 www.cell.com/cell/fulltex... [1/9]

Join us next Wednesday as we hear from the great work from the Ward lab!

Such a great time at the #IUIS2025! Inspiring conferences by amazing scientists such as @belkaidlab.bsky.social @virusesimmunity.bsky.social @linterman.bsky.social. Also loved seeing rising stars like @camilahcoelho.bsky.social @marionbrunck.bsky.social. Thanks to James Allison for his lecture !! ❤️

Congratulations to former LJI trainee Dr. Camila Coelho (now at the Icahn School of Medicine at Mount Sinai)! 🎉 Dr. Coelho has been named a "Rising Star" by Union of Immunological Societies — an award for early-stage researchers who are revolutionizing the field! bit.ly/4mGyF3H #health #medicine

Fascinating talk by rising star @camilahcoelho.bsky.social - Latin America representing @iuis-online.bsky.social #IUIS2025

🚨 New Publication!!! I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”. www.cell.com/cell-reports... [1/4]

Had a great time presenting my PhD work so far in @camilahcoelho.bsky.social’s lab at the Keystone Vaccinology meeting! Grateful for the chance to share and learn alongside such an inspiring community of scientists! #KSVaccines25

Labels matter and they influence policy. Thank you to the brilliant @camilahcoelho.bsky.social for making us rethink our default scientific terms to take away the unintended stigma to create a safer space. People like you help change the world.

We urge researchers, editors, and public health professionals to: – Reassess default epidemiological labels – Prioritize accuracy over legacy language – Center transmission routes, not identities #PublicHealth #Mpox #InfectiousDiseases #StigmaFreeScience

Check our important piece below 👇! "We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations." @thelancetinfdis.bsky.social