A huge body of work presented by our lucky last speaker of the whole conference, Dr Marcel Doeflinger from @wehi-research.bsky.social Their team has done some amazing studies into the mechanisms of long COVID and have some exciting therapeutics being developed 🦠🫶🏽💉🫁 #lorneiandi

Beautiful story from @l-beattie.bsky.social from @thedohertyinst.bsky.social revealing a new role for IL-4 from gamma-delta T cells in the CD8+ Tmem response to malaria sporozoite vaccination 💉✨🦟 Check out their recent publication: 📋 www.nature.com/articles/s41... #lorneiandi

We had Dr Shahana Ahmed from CSIRO, who gave a snapshot on transcriptomic signatures that differentiate resilient from susceptible animals in LSDV infection.🦠🐄 #lorneiandi

An interesting science bite by Carissa Aurelia from @thedohertyinst.bsky.social on the effect of bispecific IgG4 on Fc effector functions after SARS-CoV-2 vaccination. 💉 #lorneIandI

Dr Michael Leitner from @qimrb.bsky.social gave a talk on cRNA-Seq uncovered neural cell tropism and antiviral responses in human and mouse neural tissues.🧠 #lorneiandi

Thanks to Dr Sudip Dhakal from @csiro.bsky.social for a great talk in our Advances in Treatment for Infectious Diseases session 🦠 he revealed how guide RNA can be used to help in the fight against highly pathogenic avian influenza 🐣🧬 #lorneiandi

We had @mithunbge06.bsky.social, from CSIRO, who gave an interesting science bite on development of a bat airway epithelial cell model to understand innate immune features to pteropine orthoreoviruses🦇 #lorneiandi

@camilahcoelho.bsky.social just presented her amazing work on #Mpox #vaccines and #antibodies at #lorneIandI. Brilliant, enthusiastic and inspiring! She’s looking for postdocs to join her new lab in Brazil! Spread the word! 🦠🧪🫶🇧🇷

Next up in our Advances in Treatment session is PhD student Kimberley Gunther from UQ, who shared their work developing a host-directed therapy based on macrophage metabolites 💥 which enhance antimicrobial functions, to combat the huge global threat of AMR 🦠🐁 #lorneiandi

Thanks so much to our sponsor for the Advances in Treatment for Infectious Diseases Session, ✨ CSL ✨ Keep them in mind for collaborations on human therapeutics 😍 #lorneiandi

Incredibly grateful to hear a beautiful invited talk from Dr Camila Coelho @camilahcoelho.bsky.social from Mount Sinai, NY🗽, revealing the first monoclonal antibody protective against an orthopoxvirus, for developing drugs and vaccines against Mpox which urgently needs new therapies 💉✨ #lorneiandi

A great Science Bite from Anouschka Akerman, a post-doc at UQ, who showed us their team's approach for a rationally-designed T cell vaccine for malaria 🦟🧬💉 #lorneiandi

Final speaker for the Session, @harshw.bsky.social from @monashuniversity.bsky.social took us through how the metabolic shift acts as a rescue for macrophages in fungal pathogenesis. Great talk!👏 #lorneiandi

Up next Jason Paxman from La Trobe on "lazy" cell penetrating auto-transporte toxins of bacteria 🦠🦥 Shout out to Akila Pilapitiya who was the PhD student behind alot of this amazing work! #lorneiandi

Next up in the session, we had @pailene.bsky.social from @wehi-research.bsky.social gave a great talk on PTRAMP-CSS, first multi-stage malaria vaccine target💉🦟 #lorneiandi

Do you want to do proteomics but don't have a mass spectrometer? Well now you can with just PCR thanks to the #lorneiandi sponsor Olink! 🧬 If you want to learn more about "PCR for proteins" check out their website below 👇 olink.com

Our next speaker is A/Prof David Jacques from UNSW, who gave as an interesting talk on multifunctional retrovirus capsids, which act as targets for anti viral drug treatments.💊🦠 #lorneiandi

Kicking off our last day of #lorneiandi with @robmoon.bsky.social talking about zoonotic malaria, vaccines, antibodies and how maralria glides and invades RBCs featuring some amazing videos! 🦟💉📽️🐒 @lshtm-malaria.bsky.social @lshtm.bsky.social

Thanks @theviin.bsky.social for the invite to join this great meeting, and share our work on Kaptive for capsule typing, and how we can apply it to inform #klebsiella vaccines: tinyurl.com/npaj4vzr With @tomstantonmicro.bsky.social @shaunkeegan.bsky.social @katholt.bsky.social and many others

Gorgeous views of Lorne for tonight's #lorneiandi Conference Dinner at the Peak! Plus a few furry locals saying hi 🦘

Some amazing work being showcased in Poster Session II #lorneiandi 🫶🏽🦠 Looking forward to seeing everyone at The Peak later tonight 💃

Sophie Collier from @unimelb.edu.au gave her talk on investigating the role of kelch-13 during sexual and mosquito stage of development of P. falciparum.👏

Science bites session II, Lily P Kenchington-Evans from @university of Queensland gave us a talk on Design, synthesis, and biological evaluation of antibiotics decorated with a permanent charge.

Closing our session is Camila Faoro, post-doc @monashuniversity.bsky.social, giving us a snapshot of how an HLA allele shapes natural killer cell immunity in Oceania First Nations peoples. ✨🦠 Check out their poster tonight! #lorneiandi

Can yesterday’s vaccine protect against the variant SARS-CoV-2 strains of today? 🫁 Jack Jerome from RMIT revealed cross-reactive responses between viral variant peptides. Check out their poster #170 for more 🦠🧬 #lorneiandi

Thishan Illankoon from the Mater Research Institute gave us a snapshot of how the unfolded protein response impacts the immune response to respiratory infection with aging 🦠🐁👴 Check out their poster tonight! #lorneiandi

Audrey Brown from the University of Virginia 👩‍🔬 reveals how CREM dependent action leads to altered amebiasis - check out their poster #166 tonight 💉🦠🧬 #lorneiandi

@iamdrsam.bsky.social, post-doc at CSIRO gave a great science bite on how we can prioritise animal welfare when undertaking virology and immunology research 🐷. Check out her poster #137 tonight 👩‍🔬🦠🫶🏽 #lorneiandi

Next up in SBI, we had @faolivier.bsky.social from @monashuniversity.bsky.social, they gave a great quick talk on transcriptomic and morphological profiling of candida albicans liquid suspension biofilms 🧫 🔬 - go to their poster #158 tonight to play a game and win a T-shirt! #lorneiandi

Jen @habeljen.bsky.social from @thedohertyinst.bsky.social presents on the impacts of pregnancy on virus-specific cytotoxic T cells, and the implications for responses to chronic viral infections! ✨ Check out her poster tonight! #lorneiandi

Dr Cameron Bastow kicking off a great first half of our science bites II sessjon featuring Eithne Cunney, Xiaohu Zhao, Byron Mobbs and Elizabeth Mullens 🧬🧫

Continuing the Science Bites is Leslie Dominguez Cadena from UQ, revealing how macrophages respond to mycobacterial infection 🦠 and produce signals important for T cells and control of infection! 💪 Check out their poster tonight! #lorneiandi

Great to hear from Joshua Levendis @unimelb.edu.au in Science Bites I, revealing how the RNA modification m6A facilitates 3' formation in P. falciparum mRNA 🦟🩸 make sure to check out their poster later tonight #lorneiandi

Kicking off Science Bites session I is Julianne Hamelink from @burnetinstitute.bsky.social, showing how ruxolitinib treatment impacts B cell immunity in a malaria human challenge trial 💥🦟 Be sure to check out our speakers' posters this evening! #lorneiandi

Our last speaker for the adaptive immunity session is Dr. Dimitra Chatzileontiadou from La Trobe University gave us a great talk on HLA-A*03:01 association with COVID-19 vaccine side effect.💉 #lorneIandI

A masterclass from Dr. Chris Overall from the University of British Columbia to cap-off the session 👏 Snippets stories on how SARS-CoV-2 main Protease (3CLpro) targets not only the viral polyprotein, but also host targets & staggering evidence of immune escape by Tunnelling Nanotubes #lorneiandi

Our penultimate speaker in the Adaptive immunity session at #lorneIandI is Holly Fryer @hollyfryer.bsky.social from @monashuniversity.bsky.social presenting her work with @precisionvaxlab.bsky.social studying the human germinal centre response to Strep A derived glycans 🦠

Interesting talk from Dr @ramadhenni.bsky.social from @burnetinstitute.bsky.social about developing a human lymphoid organ model, as an efficient platform to study human malaria vaccine responses. 🧫💉 #lorneIandI

Next up in the emerging infectious disease threats session we had our invited speaker @kelwyres.bsky.social from @monashuniversity.bsky.social who shared how genomic surveillance can be used to inform anti-Klebsiella pneumoniae vaccines to save babies from neonatal sepsis 🍼🦠💉 #lorneiandi

@christophermccrory.bsky.social from @thedohertyinst.bsky.social explains how H. pylori leverages membrane vesicles for horizontal gene transfer. Incredible insights into microbial survival strategies! 🦠🧬📩

Next up in our adaptive immunity session at #lorneIandI is Dr Ahmed Abdul Quadeer from @unimelb.edu.au presenting his cutting-edge research using AlphaFold3 to study Hepatitis C specific antibodies

Next we had Prof @katherinekedz.bsky.social, from thedohertyinst.bsky.social took us through the underline immune signatures of virus-specific CD8+ T cells in healthy aging, highlighting the importance of understating the immune responses changes thought our life time. #lorneIandI

Can you teach an "old drug" new tricks 🤹? Or rather find an old drug that can treat Alphaviruses like chikungunya virus (CHIKV) using new techniques 💊? Lara Herrero gave a fabulous talk about how they are using a digital spatial imaging technique to do just this! #lorneiamdi

Continuing with our Emerging Diseases section, Maria Gancheva from the University of Adelaide shared her interest in novel drug treatments using natural products to fight single cell eukaryotic parasites 🌱 🦠

First up in our Emerging Infectious Disease Threats session we had an insightful talk by Naphak Modhiran ft. the amazing PhD work of Morgan Freney and lots of protein structures! We learnt all about the antigenic and structural diversity of Japanese Encephalitis Virus (JEV) genotypes #lorneiandi

Our first speaker for this afternoon’s adaptive immunity session at #lorneIandI is Prof Tri Phan @labphan.bsky.social, giving a wonderful presentation outlining the role of macrophages in the antibody response to vaccination

Over the lunch break on day 2 of #lorneIandI we held a fantastic networking session where our students and ECRs had a chance to speak to our invited speakers and sponsors. Thanks to everyone involved for a highly engaging session!

Thanks VIIN for the chance to share our work! Great to be back in sunny Lorne for this meeting

Student and ECR Networking event happening now at #Lorneiandi! @theviin.bsky.social

To conclude our mucosal & microbiome session, Sam Forster, lab head at @ciiid-hudson.bsky.social, spoke about how understanding microbial community dynamics can help design microbiome-modifying live biotherapeutics to combat a plethora of diseases including IBD 🧫🦠 👏 #lorneiandi