Goran Bajic
@gogo-science.bsky.social
📤 325
📥 156
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Structural biologist interested in all things antibody and viruses. 🏳️🌈 bajiclab.org
reposted by
Goran Bajic
Ian Weissman, DO
6 days ago
"The Trump administration in May canceled a $700 million contract with Moderna to develop a human bird flu vaccine. Secretary Kennedy has cut other funding for vaccine research and scrapped long-held federal vaccine guidance."
www.reuters.com/business/hea...
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US senators push USDA for urgent action on bird flu vaccine
A bipartisan group of U.S. senators this week urged the administration of President Donald Trump to finalize a science-based plan for developing a bird flu vaccine for livestock, according to a letter...
https://www.reuters.com/business/healthcare-pharmaceuticals/us-senators-push-usda-urgent-action-bird-flu-vaccine-2025-12-11/
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Goran Bajic
Jeremy Berg
16 days ago
New York Times article on science funding with some depressing but familiar curves with interactive graphics.
www.nytimes.com/interactive/...
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The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
https://www.nytimes.com/interactive/2025/12/02/upshot/trump-science-funding-cuts.html?unlocked_article_code=1.5k8.-Yuf._rLIqKb0F-aK&smid=url-share
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Goran Bajic
SBGrid Consortium
29 days ago
SBGrid's eLife paper received a citation in October
[email protected]
from Icahn School of Medicine at Mount Sinai in
@science.org
Immunology. Read more here:
buff.ly/s8uVL86
#SBGrid
#ScienceMatters
#StayConnected
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Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunization
SARS-CoV-2 variant booster vaccination broadens human B cell responses through the germinal center reaction.
https://buff.ly/s8uVL86
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Goran Bajic
Science News
about 2 months ago
How to develop good research questions "This Comment describes the iterative creative process for designing good research questions, and includes practical suggestions and ways to avoid common traps."
www.nature.com/articles/s41...
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reposted by
Goran Bajic
about 2 months ago
**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact:
[email protected]
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Read the latest from us here:
www.science.org/doi/10.1126/...
#antibody
#cryoEM
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Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunization
SARS-CoV-2 variant booster vaccination broadens human B cell responses through the germinal center reaction.
https://www.science.org/doi/10.1126/sciimmunol.adu4107
2 months ago
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Goran Bajic
Magnus Bauer
3 months ago
Phosphorylation on tyrosines control key pathways in immunity, cancer, and metabolism. For the first time, we can now design proteins that specifically recognize individual phosphotyrosines, even in disordered regions. (1/8) Preprint:
www.biorxiv.org/content/10.1...
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Goran Bajic
Current Biology
4 months ago
Feeling mitochondrially challenged lately? Here are two classic reviews on
#mitochondria
that should help.
www.cell.com/current-biol...
www.cell.com/current-biol...
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The Origin and Diversification of Mitochondria
Moving beyond the simplistic view of mitochondria as the power house of the cell, Roger et al. present the immense diversity of mitochondria and mitochondrial functions across eukaryotes, and bring th...
https://www.cell.com/current-biology/fulltext/S0960-9822(17)31179-X
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Goran Bajic
Seth Thomas Scanlon
4 months ago
Heads up:
@science.org
is looking for a new research
#editor
based in the US or UK to handle papers in
#InfectiousDiseases
(e.g.,
#virology
,
#microbiology
,
#parasitology
) &
#microbiome
research! This is an amazing opportunity, so don't delay! Applications are due 22 SEP!
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https://recruiting.ultipro.com/AME1123ASEM/JobBoard/07f12c2c-f20e-42f2-b442-dbab6fe420be/OpportunityDetail?opportunityId=95fcca02-48f8-4872-be17-2b164ed14a41
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New paper from the Coelho lab with a modest contribution from us:
add a skeleton here at some point
4 months ago
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reposted by
Goran Bajic
Camila Coelho, PhD MBA
4 months ago
🚨 New Publication!!! I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”.
www.cell.com/cell-reports...
[1/4]
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Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope
Rao et al. demonstrate that convergent somatic hypermutations in the light chain, enriched within a sarbecovirus-specific public antibody clonotype, drive affinity maturation. This antibody targets a ...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00893-9
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The latest from us:
www.cell.com/cell-reports...
With Camila Coelho’s lab, we describe how public clonotype
#antibody
affinity matures against an occluded epitope on
#spike
we call the central interface epitope!
#cryoEM
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Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope
Rao et al. demonstrate that convergent somatic hypermutations in the light chain, enriched within a sarbecovirus-specific public antibody clonotype, drive affinity maturation. This antibody targets a ...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00893-9
4 months ago
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Goran Bajic
cryoEM papers
5 months ago
Mix-it-up: Accessible time-resolved cryo-EM on the millisecond timescale
www.biorxiv.org/content/10.1101/2025.07.22.666177v1
#cryoem
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reposted by
Goran Bajic
Seth Thomas Scanlon
6 months ago
To celebrate
@focisimmunology.bsky.social
's annual meeting this week,
#Science
#Immunology
has just released a new free sample collection of recent papers with a focus on human immunology! The collection will be available online to read until the end of July 2025!
#FOCIS2025
bit.ly/SciImm_free
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Another fruitful collaboration with the Coelho lab!
www.sciencedirect.com/science/arti...
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7 months ago
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Latest from us: another productive collaboration with the Schmidt lab on
#flu
#antibody
www.science.org/doi/10.1126/...
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Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies
Broadly reactive human antibodies recognizing the head and stem of influenza hemagglutinin.
https://www.science.org/doi/10.1126/sciadv.adu9140
8 months ago
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Can’t wait to try this new feature out!
add a skeleton here at some point
8 months ago
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All props to our students, Vishal and Iden, who spearheaded this study!
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9 months ago
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Really disappointed with
#HHMI
www.science.org/content/arti...
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HHMI kills program aimed at boosting inclusivity in STEM education
“Inclusive excellence” program had committed $60 million to 104 institutions
https://www.science.org/content/article/hhmi-kills-program-aimed-boosting-inclusivity-stem-education
10 months ago
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Our long-awaited study in collaboration with the Schmidt lab on H5Nx influenza recognition by naive B cells is out!
#antibody
#bcell
#flu
#avianflu
#cryoEM
www.science.org/doi/10.1126/...
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Human naïve B cells recognize prepandemic influenza virus hemagglutinins
Antibodies targeting the influenza hemagglutinin from potentially pandemic H5Nx viruses can be isolated from naïve individuals.
https://www.science.org/doi/10.1126/sciimmunol.ado9572
11 months ago
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Tonight is a fun night of proofreading manuscript journal proofs with Dionne Warwick in the background.
#staytuned
11 months ago
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reposted by
Goran Bajic
John Rubinstein
12 months ago
We are hosting a cryo-EM grid nanofabrication workshop on 28 April 2025, as part of the Canadian Cryo-EM Nexus (
ccemn.ca
). Learn how to make holey gold or holey carbon grids in your own laboratory! Space is limited, so please apply at
web.cvent.com/event/ee88ac...
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Latest from us:
www.biorxiv.org/content/10.1...
Antibody 52 hits every variant we tested.
#cryoEM
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Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein
SARS-CoV-2 mRNA vaccines induce robust and persistent germinal centre (GC) B cell responses in humans. GCs are microanatomical sites in lymphoid tissues where diversification and affinity maturation o...
https://www.biorxiv.org/content/10.1101/2024.12.06.625234v1
about 1 year ago
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reposted by
Goran Bajic
Jesse Erasmus
about 1 year ago
Couldn’t find a virology starter pack so here’s one to get the ball rolling. Repost/reply if you are a virologist so I can find and add you to the list!
go.bsky.app/SinqoJU
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