🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

Excited to head to Japan in November to present at the CSHA meeting on Immunoreceptor Signaling and Therapeutic Applications. Abstract deadline is next week! www.csh-asia.org?content/1343

It was a privilege and a pleasure for both myself and @menezesnmaria.bsky.social‬ to preview a great upcoming article in @cp-immunity.bsky.social‬ by @kamphorstlab.bsky.social‬ showing an unexpected inhibitory role for ICOS in exhausted CD8+ T cells. www.cell.com/immunity/abs...

BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.   How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?  Trump must end this illegal funding freeze.

Hopefully a nudge in the right direction thehill.com/homenews/543...

Our paper is out! Check out this beautiful story where we uncovered that the costimulatory molecule ICOS is detrimental for PD-1+ CD8 T cells. Sustained ICOS signaling reduces memory-like features of progenitor exhausted CD8 T cells in chronic viral infection and liver cancer.

These are extremely challenging times for early-career faculty. Here is my office's small contribution to make their hard and important work a bit easier: Download our curated and comprehensive database of funding opportunities for early-career faculty. Here: research.jhu.edu/rdt/funding-...

By itself, this is certainly not the most important issue we're confronting right now. But it's emblematic of the pervasive, destructive, anti-science efforts. Gift link www.nytimes.com/2025/02/26/c...

I am sure a lot more science programs will have to make these tough decisions

'In 2024, a budget cut of €900m shocked the scientific community. More recently, additional amendments to this budget proposed further cuts of €630m, along with an extra €534m reduction to the France 2030 program. These cuts threaten not only basic research but also higher education'

We are too! DM me or find me on Signal at zacharybrennan.20

Donald Trump and Elon Musk’s idea of efficiency is stopping research on curing cancer.

March is still a long time from now. We need to stop the bleeding. Talk to your patients. Reach out to your patient advocates and community scientist - call your representatives! Make some noise.

Use this form to tell us how the new US administration is affecting your research, or suggest future coverage https://go.nature.com/42SyoUu

In my lab, we analyze patient samples and develop preclinical models to understand why some patients respond to immunotherpies and others don't. We write grants to support our research. Only 9%, really the top, are funded. But now, NCI/NIH tare not awarding grants even to top scores.

Internal NIH guidance updated yesterday. Just canceling stuff each day from here on out I guess, pending new guidance. Killing science off both slowly and incredibly rapidly.

ATTENTION If anyone has received a NoA after the "pause", please DM me with information about the mechanism and institute or center. THANK YOU

The deadline to submit an abstract for a poster presentation is Feb 20. Register now 👉 hubs.la/Q034zC0H0 #KSCancerImmune25

So the first year of one our #NIH grants ended on 1/31 and we have not received the Notice of Award for year 2. I'm so confused now--is there an NIH freeze or not? Wasn't it blocked by a judge? Has anyone else received a NOA since this debacle? #academicsky #medsky

Absolutely. Dozens of them. See also www.chronicle.com/article/were...

Press release by the appropriations subcommittee on NIH budget slashing by @delauro.house.gov 🙏

awful

YES. Need to say this loudly and often! This 2.46x is also the short-term ROI. Long-term ROI (more difficult to estimate) may ~10x. Highest for any gov't spending. And the source of discoveries necessary for all new drugs (industry important too but without NIH funded science there's no foundation)

First time calling politicians - it felt GOOD! Empowering - might call them again tomorrow, and the day after - get out there! this 5calls website will tell you who to call and provide a draft script #science will #prevail. 5calls.org/issue/nih-ns...

The loss of AMERICAN science will have ripple effects on jobs and economic growth. At the same time China and other countries are investing heavily in science @schumer.senate.gov @nadler.house.gov

@altnih4science.bsky.social Are study sections and council meetings happening at NIH this week?

Extremely disappointed to see HHMI decide to kill their Inclusive Excellence program, including terminating the current IE3 awards to over a hundred institutions effective this year in the middle of a 6-year grant. I was hoping HHMI (and other private funders) would continue to lead the way.

NIH website down. 😱

I am one of these NSF postdocs. NSF has frozen everyone’s access to their salaries and research stipends (that were already awarded) with no information about when they might be expected to be unfrozen. It still appears like we are expected to continue doing our work though.

Immunology will be for everyone, everywhere, everyday, from driving foundational research to reaping the benefits for health. 🌎 Immunoschool 2025 is open for anyone looking to learn more about key immunotherapy advances over the last decade. FREE TO REGISTER: www.eventbrite.com/e/internatio...

"Contrary to current approaches involving rigorous documentation and standardization, we postulate that increasing species diversity can improve microbiota stability and mouse physiology, enhancing robustness, reproducibility, and experimental validity." www.cell.com/trends/immun...

Super excited to be presenting our work at this great meeting!

The inaugural AACR IO Conference on Discovery and Innovation in Cancer Immunology takes place February 23-26 in Los Angeles. Learn why Dr. Antoni Ribas says #AACRIO25 is “the must-attend immuno-oncology event of the year."  www.aacr.org/about-the-aa...  #AACRStories

Recently finished your PhD or plan to in early 2025 and love #Tcell biology, particularly #gdTcells? We're recruiting a #NIDDK-funded #postdoc @sinaiimmuno.bsky.social! We'd love to have an #immunologist with expertise in #GIsky or #IBDsky join our team. bit.ly/4izpZLj #Immunosky