Poster deadline is approaching for @keystoneSymposia.bsky.social #BCells & #PlasmaCells : Fundamental & Translational Biology, this March in Keystone! keysym.us/KSBCells26 #KSBCells26

Target stiffness influences T cell polarization and gene expression through distinct Ca2+ channels www.science.org/doi/10.1126/...

One-step generation of TCR knock-in mice targeted to the TCRβ locus results in functional mature T lymphocytes https://www.biorxiv.org/content/10.64898/2026.01.13.699338v1

Urs Mörbe, William Agace et al. characterize and spatially map the fibroblast landscape within human large and small intestinal gut-associated lymphoid tissues, including Peyer’s patches and isolated lymphoid follicles, during homeostasis and #Crohns disease. rupress.org/jem/article/... #IBD

IgA plasma cell dynamics during homeostasis and immunization @cp-immunity.bsky.social Preview @carlanowosad.bsky.social www.cell.com/immunity/ful... on www.cell.com/immunity/ful... www.cell.com/immunity/ful...

My latest 'pinch yourself' moment from the Lab. We previewed two really really exciting papers from the Eisenbarth and Pabst Labs for @cp-immunity.bsky.social Read our summary here> www.cell.com/immunity/ful... A big well done to Gaby Berman in my group and authors of both excellent manuscripts!

Absolutely thrilled to put this into the world-first Nowosad Lab preprint is live 🥲 Check out what me and @thelundlab.bsky.social get up to when left to our own devices. Full breakdown to come, but for now let us know what you think. @nyulangone.bsky.social www.biorxiv.org/content/10.1... #immunosky

Taxpayers should not accept cuts in funding for cancer research. Bravo 👏🏾👏🏾👏🏾👏🏾👏🏾 @miriammerad.bsky.social 👇🏼👇🏼👇🏼Sign up to show New York State law makers that you want your tax dollars to fund life saving research www.nycures.org

Leaving Basel after an amazing @embo.org meeting on Barrier Immunity! Bravo @maurogaya.bsky.social and @immunologyking.bsky.social for putting together such a brilliant lineup.

Great analogy to illustrate the question @carlanowosad.bsky.social is pursuing on her lab: how GC are form and how GC cells find their way to their specific locations #embo workshop Basel #immunalogy

Fantastic @embo.org young investigator lecture on lung B cell responses from @maurogaya.bsky.social #EMBObarrierTissues

Vote for the extremely talented Helena here!!

Why does selection feel so weak relative to mutation in affinity maturation? A new blog post giving three perspectives, including our new transformer-based model of natural selection on antibodies: matsen.group/general/202...

Love this series! Great to see some familiar faces in here 😎

🧪 Senate appropriators say: NIH's budget gets a... boost! Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%). "Congress has your back," said @murray.senate.gov. ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.

BREAKING: Trump wants to illegally cut off $15 billion in lifesaving NIH research. Research to cure cancer, Alzheimer's, and so much more is on the line. These people are LYING about waste, fraud, and abuse at NIH to justify attacking medical research—we all need to say so. My full statement. ⬇️

Starting up OnlyLabs, where people can pay to watch researchers who used to have federal funding do Hot Uncensored Cutting Edge science experiments.

Nowosad Lab will be recruiting postdocs soon. Reach out if you are interested!

S1P is produced in the outer lymph follicle area and degraded by B cells resulting in a negative gradient towards to follicle center. S1PR2 signalling on GC B cells leads to migration arrest, keeping B cells within the follicle. (🐭 data) Green et al 2011 🧪⑂ www.nature.com/articles/ni....

'Under the new administration, the NIH, which for more than 75 years has supported scientists who are pursuing research deemed to be in our national interest, is pulling back. Budgets are being slashed.'

Big day for the lab today 🧪

Congrats to Gaby Berman, officially a Nowosad Lab PhD candidate!!

Please share this widely and encourage students to apply! Many of our current graduate students were recruited through this program -- happy to answer any questions and connect with students bsky.app/profile/stan...

Cream puffs in a tip box can only mean one thing… a celebration! Nowosad Lab milestone- first student qualifying exam complete 🥲

The astounding contribution of US academic science to new medicines www.statnews.com/2025/06/06/u...

NEW: Important Context spoke with a dozen people working at NIH about Director Jay Bhattacharya. The descriptions were universally unflattering, painting the health economist as ineffectual, dishonest, ideological, arrogant, and uncommitted to science. www.importantcontext.news/p/out-of-his...

The bottom line with the proposed cuts to NSF is to cut the number of working scientists and disappear opportunities to train new scientists. This is a PROPOSED budget to Congress. Call your reps.

Presidential budget proposes a 70% reduction in NSF funding for 2026 compared to2024. Instead of funding 23% of proposals (2024) they will fund 7% (2026). A perfect recipe for the destruction of American science.

Not one, not two .... but FIVE recent papers highlighting a role for RORgt+ antigen-presenting cells in the gut in establishing tolerance to food antigens #oraltolerance #immunosky #foodallergy

Last chance TODAY - to register and submit abstracts for #EMBObarrierTissues in Basel 🇨🇭🇨🇭🇨🇭! We've hit our registration goal 🥳, but there's always room for more. Join @maurogaya.bsky.social and me to explore the latest in lymphocyte and mucosal immunology. Details: meetings.embo.org/event/25-bar...

The last few days were a much needed reminder that community is everything in science. Thanks V Foundation, you guys are the coolest.

Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome @natcomms.nature.com www.nature.com/articles/s41...

Non-cognate B cells can enter germinal centers, undergo SHM, and acquire new antigen specificities, highlighting the capacity of antibodies to generate new recognition through SHM @cp-immunity.bsky.social www.cell.com/immunity/ful...

Misinformation is winning not because it's true, but because it’s loud, emotional, and everywhere. It’s time for science to fight back. Aaron Mertz and I dissect the issue and offer solutions 👇 📖 www.nature.com/articles/s41... #SciComm @sinaiimmuno.bsky.social @aspeninstitute.bsky.social

Online now: Somatic hypermutation unlocks antibody specificities beyond the primary repertoire

while we wait for #adaptive #tissue #immunity to take off in August ... join us!!! register by end of May meetings.embo.org/event/25-bar... @eurovision.tv #ArtBasel youtu.be/xyTEK-jUlZo www.youtube.com/watch?v=bi2Y...

Sen. Ossoff: Who out there in the American public is sitting at home demanding that we shut down cancer research and Alzheimer's research?

This is going to be great, join us!

Final hours to apply for the SMI Mentorship Program! Advance your scientific career and expand your network by taking advantage of this valuable SMI member benefit. Get connected with a senior PI for a two-year, career-shaping mentorship experience. Apply today! bit.ly/3EU4FAW

Had the most fabulous day at Stanford today. Thanks all for coming to my seminar and being so interactive!

Fantastic talk from @carlanowosad.bsky.social on B cells and clonal selection - so much cool data! 🤩

This week we'll be visited by @carlanowosad.bsky.social from NYU Grossman School of Medicine for a @britsocimm.bsky.social MIG Seminar on lymph node lymphangiogenesis and regulation of the germinal center response. 📅 Thursday 17th April 🕐 12 pm 📍 Michael Smith Lecture Theatre #ImmunoSky

One of our obsessions in the Crotty lab is to better understand B-cell immunology in the context of vaccines. Rare B cells can have antibody specificities particularly important for protection against some diseases. In our most recent paper… @cp-immunity.bsky.social www.cell.com/immunity/ful...

Fascinating and important!!

Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis www.cell.com/cell-host-mi...

Review @natrevimmunol.bsky.social @acasadevall1.bsky.social New insights into antibody structure with implications for specificity, variable region restriction and isotype choice www.nature.com/articles/s41...

Cool germinal center acrobatics from Juhee Pae et al, check it out! www.nature.com/articles/s41...

Growth of the maternal intestine during reproduction @cellcellpress.bsky.social @irenemiguel-aliaga.bsky.social www.cell.com/cell/fulltex...

Great to have our latest review "The cellular factors that impair the germinal center in advanced age" out @jimmunol.bsky.social. Work led by @wsfoster.bsky.social and Edith Marcial-Juárez. With @sanmarti92.bsky.social creating the beautiful GC images in figure 2. doi.org/10.1093/jimm...

Jang, Reizis et al. report that when the activating Kras mutation arises in hematopoietic #stemcells, it causes the expansion and reprogramming of multipotent progenitors. rupress.org/jem/article/...