Online Now: Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 Online now:

Looking very much forward to the 2nd edition of the Fusion Conference on Spatial Genome Organisation #SGO25 @fusionconf.bsky.social @karimmekhail.bsky.social @chiololab.bsky.social. Early bird registration closes soon: June 2nd, 2025. Slots available for selected talks from abstracts: bit.ly/4492G6i

The first cancer-related story from our group @WeillCornell is now published in @MolecularCell. We investigate the role of hyperconnected 3D regulatory hubs in controlling oncogenic programs and properties in glioblastoma and also across 16 cancer types. www.cell.com/molecular-ce...

Melanie Woodin, an internationally recognized neuroscientist who studies the mechanisms underlying learning and memory in the brain, has been named #UofT’s 17th president. ➡️ uoft.me/uoftpres

Our new findings on how chromosomes get ready for cell division are now published in @cellpress.bsky.social! Congratulations, Kai, @andibrunner.bsky.social and everyone else involved! 🤩 www.sciencedirect.com/science/arti...

The final piece of my postdoctoral work in the @freudlab.bsky.social was recently published! Quite amazing what this small little repair polymerase can do to fill 1-nt gaps in chromatin. www.nature.com/articles/s41...

This RNA modification drives prostate cancer progression Our recent study reveals that m6A RNA modification promotes prostate tumour growth and relapse. Specifically, it boosts the production of a cell movement molecule to aid cancer metastasis. www.nature.com/articles/s41...

Our latest article, in collaboration with Helle Ulrich, explores how the timing of lesion bypass and gap processing impacts genome stability. doi.org/10.1093/nar/...

Horizontal mitochondrial transfer in cancer biology: Potential clinical relevance www.cell.com/cancer-cell/...

🚨 Excited to announce the 2nd Spatial Genome Organisation Conference! #SGO25 📅 Oct 31–Nov 3, 2025 | 📍 Riviera Maya, Mexico 🪑 Chairs: @altmeyerlab.bsky.social, @chiololab.bsky.social, @karimmekhail.bsky.social 🔗 Registration: fusion-conferences.com/conference/188 Please 🔄 ❤️

The source code for AlexNet – the neural network developed at #UofT that kickstarted today’s AI boom & led to a Nobel Prize – will be preserved by the Computer History Museum in partnership with Google. 💻 uoft.me/bqR

I've reviewed 10 consumer-facing companies that are in the business of promoting longevity and healthspan erictopol.substack.com/p/the-busine... Open-access, in the new edition of Ground Truths

Come start your lab in beautiful Strasbourg 🇫🇷 www.nature.com/naturecareer...

Why AI won’t replace scientists capable of making disruptive conceptual breakthroughs - they pose questions that challenge, rather than align with, the training data set thomwolf.io/blog/scienti...

As relevant today as ever: “An eye for an eye only ends up making the whole world blind.” Mahatma Gandhi

A unified model for cohesin function in sisterchromatid cohesion and chromatin loop formation: Molecular Cell www.cell.com/molecular-ce...

Almost 17 years after opening our yeast cell division lab, our first transcription paper in mouse embryonic stem cells! www.science.org/doi/10.1126/...

🚀 New Paper Alert! Our latest @natrevmcb.bsky.social explores how nuclear and genome organization drive DNA double-strand break repair! 🧬 📖 Free access: rdcu.be/edViW Please 🔄 ❤️

1/Out today in @naturecomms.bsky.social, “A CPC-shelterin-BTR axis regulates mitotic telomere deprotection”. Here we identify the mechanism that unwinds telomere-loops (t-loops) during mitotic arrest to activate the DNA damage response and signal mitotic stress. www.nature.com/articles/s41....