Another paper bluetorial! Today: how does the spatial location of genes influence their function? (1/n) www.nature.com/articles/s41...

Online Now: Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 Online now:

Happy to share the latest story from @arnaudkr.bsky.social's lab @embl.org! With @guidobarzaghi.bsky.social, we used Single Molecule Footprinting to quantify how often chromatin is accessible at enhancers after TF and chromatin environment changes! Check our preprint bit.ly/3XQMFxN + thread ⬇️ 1/11

Easily one of the most beautiful live-cell imaging papers out there! Amazing contribution to chromosome tracking during mitosis with huge prospects for further discoveries concerning chromosome behavior. Check it out @naturecellbiology.bsky.social

New preprint from our lab! Why is not everyone working on Transposons? Loss of H3K9me3 maintenance in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons www.biorxiv.org/content/10.1...

Excellent thread on the paper from Meneu, Chapard et al. The latest from the Koszul and friends lab! www.science.org/doi/10.1126/...

One of the co-Editors-in-Chief (Martin Kulldorff) published a "Perspective" entitled "A Blueprint for NIH Reform". publichealth.realclearjournals.org/perspectives... 2/n

Peter Marks’s resignation letter. Everyone should read this.

📢The programme for #DDRCT25 is now available! Visit our website to explore the exciting sessions, speakers, and key topics we have in store. ➡️Check it out here: fusion-conferences.com/conference/177

Check out our review on DNA end resection! With Raphael Ceccaldi, www.nature.com/articles/s41...

Our new findings on how chromosomes get ready for cell division are now published in @cellpress.bsky.social! Congratulations, Kai, @andibrunner.bsky.social and everyone else involved! 🤩 www.sciencedirect.com/science/arti...

🚨 Excited to announce the 2nd Spatial Genome Organisation Conference! #SGO25 📅 Oct 31–Nov 3, 2025 | 📍 Riviera Maya, Mexico 🪑 Chairs: @altmeyerlab.bsky.social, @chiololab.bsky.social, @karimmekhail.bsky.social 🔗 Registration: fusion-conferences.com/conference/188 Please 🔄 ❤️

Landing on Bluesky by sharing the latest preprint from the lab: nucleoplasmic Lamin A/C modulates RECQ1-mediated fork restart upon mild genotoxic stress, by regulating heterochromatin marks and ADP-ribosylation levels at replication factories www.biorxiv.org/content/10.1...

📣 Join us for #EESNucleus 🧬 Explore the dynamic world of the nucleus at the new EMBO | EMBL Symposium. From nuclear mechanics to pathomechanisms, join the conversation shaping modern cell biology. 🗓️ 18 – 21 November 2025 📥 Submit your abstract by 26 August 👉 https://s.embl.org/ees25-07-bl

As federal funding for research is uncertain, we need to diversify funding sources for our PhD students. Here is a comprehensive list of >160 PhD fellowships and funding opportunities, mostly from private foundations and scientific societies. Download it here: research.jhu.edu/rdt/funding-...

Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇

New discovery from our #CDlab reported in Cell @cp-cell.bsky.social today: SMC motor proteins have a left-right ‘gearbox’ and can switch direction in DNA loop extrusion! www.sciencedirect.com/science/arti... 1/

I put together a small guide on how to get started with Fiji. Please distribute to anyone who might benefit form this! zenodo.org/records/1477... #imageanalysis #fiji #imagej #training

A unified model for cohesin function in sisterchromatid cohesion and chromatin loop formation: Molecular Cell www.cell.com/molecular-ce...

1/Out today in @naturecomms.bsky.social, “A CPC-shelterin-BTR axis regulates mitotic telomere deprotection”. Here we identify the mechanism that unwinds telomere-loops (t-loops) during mitotic arrest to activate the DNA damage response and signal mitotic stress. www.nature.com/articles/s41....

🚀 New Paper Alert! Our latest @natrevmcb.bsky.social explores how nuclear and genome organization drive DNA double-strand break repair! 🧬 📖 Free access: rdcu.be/edViW Please 🔄 ❤️