First trip to Weatern Canada for ECR workshop and #CCRC2025 in #Calgary. Terrific time making new connections in #cancerresearch and reconnecting with colleagues @pmresearch-uhn.bsky.social @sickkidsto.bsky.social.

Congratulations to our Senior Scientist Dr. Rama Khokha on receiving the renewal of Canada Research Chair funding!

We are proud to recognize John E. Dick of @pmresearch-uhn.bsky.social as a #CitationLaureate 2025 in Physiology or Medicine. Congratulations and thank you for the hospitality @pmresearch-uhn.bsky.social! #CitationLaureates #Clarivate #ResearchImpact

The Lancet Oncology Commission—co-led by our Dr. Gary Rodin @uhn.ca—calls for urgent action to address the human crisis in cancer care. Survival is improving, but psychological, social and cultural support must be core to care. www.sciencedirect.com/science/arti... @uhnresearch.ca @thelancet.com

🏆 We were honoured to welcome guests from @clarivateag.bsky.social to @uhn.ca's Princess Margaret Cancer Centre for a special award ceremony recognizing Dr. John Dick as a 2025 Clarivate Citation Laureate for his pioneering work in #leukemia stem cell research. www.uhnresearch.ca/news/uhn-sci...

A new tumour-customizable nanomedicine system showed efficient mRNA delivery to cancer cells in melanoma and triple-negative breast cancer preclinical models while minimizing harmful effects in healthy tissues. Developed by Dr. Bowen Li @uhn.ca UofTPharmacy: www.pharmacy.utoronto.ca/news-announc...

3 upcoming seminars we are stoked about! - @pmresearch-uhn.bsky.social's @vukstambolic.bsky.social - #ohribmc Dr. Piriya Yoganathan - @ulaval.ca's Dr. Jean Désy Qs? Email us: [email protected] @andrewcraigscri.bsky.social @mulliganlab.bsky.social @drpostovit.bsky.social @queensuhealth.bsky.social

A team led by Dr. Benjamin Lok has found a new target to enhance radiation therapy in small cell lung cancer. By removing the function of gene HDAC3, cancer cells became more sensitive to radiation and tumour growth was inhibited: aacrjournals.org/mct/article/...; www.uhnresearch.ca/news/increas...

A new generation of Porphysomes showed an 11-fold increase in cancer cell uptake and longer-lasting immunity against tumour recurrence in preclinical phototherapy studies, led by Drs. Gang Zheng and Juan Chen's team at UHN's Princess Margaret Cancer Centre. pubs.acs.org/doi/10.1021/...

Congratulations to our Medical Oncologist Dr. Robert Vanner, whose team was awarded $1 million through 2025 Translational Research Grant in Brain Cancer to advance glioblastoma research, jointly funded by @braincanada.bsky.social and the Cancer Research Society 🎉 braincanada.ca/announcement...

Congratulations to our Dr. David Kirsch on being elected to the National Academy of Medicine for advancing sarcoma care! nam.edu/news-and-ins... uhnresearch.ca/news/top-hon... @uhn.ca @uhnresearch.ca @nam.edu

How do we SEE what’s happening in a tumour? 👀 Meet Dr. Ralph DaCosta, an optical physicist turned cancer researcher @uhn.ca's Princess Margaret Cancer Centre. His team turns the hidden world of tumour microenvironment into a colourful map to guide treatment. www.youtube.com/embe...

A pivotal moment in global cancer research collaboration 🔬 We recently hosted the inaugural C8 Symposium, uniting top scientists from 8 global institutes to tackle cancer’s toughest challenges through collaboration & innovation. www.uhnresearch.ca/news/uniting... @uhnresearch.ca @uhn.ca

Congratulations to our Senior Scientist Dr. John Dick, on being named as a Citation Laureate 2025 by Clarivate. This prestigious recognition honors researchers whose work is considered to be of Nobel-class calibre—advancing science and shaping the future of society. clarivate.com/citation-lau...

Dr. John Dick @uhn.ca, the only Canadian 2025 @clarivateag.bsky.social Citation Laureate, is recognized for his research on #leukemia stem cells driving cancer relapse. 🔗Read more: www.uhnresearch.ca/news/uhn-sci...

🔬 New study from Dr. Alex Vitkin's team shows that adding high-res optical imaging helps explain and inform low-res MRI signals. This enables quantification of important microvascular details in tumours for more precise clinical cancer imaging. ieeexplore.ieee.org/abstract/doc... @uhnresearch.ca

#PostdocAppreciationWeek 👋 Meet Giulia Kassab, a postdoc researcher at @pmresearch-uhn.bsky.social. Read about her work in using light-activated molecules and nanoparticles, and her hope for the future of health research! > www.uhnresearch.ca/news/giulia-... @uhn.ca

🎉 Newsweek has ranked UHN’s Princess Margaret Cancer Centre as Canada’s #1 cancer hospital and among the top 10 globally in its 2026 World’s Best Specialized Hospitals list! Thank you to our teams and patients — your dedication and trust makes this possible. rankings.newsweek.com/worlds-best-...

New research from @pmresearch-uhn.bsky.social shows how genetic changes in an important signalling pathway (KEAP1/NRF2) can drive radiation resistance in head & neck cancer—opening the door to new strategies that could make therapies more effective. 🔗 Read more: www.uhnresearch.ca/news/genetic...

Very proud to have been given the opportunity to contribute to this studyled by the excellent Dr. Jennifer Knox, showing us upfront molecular profiling is possible and can make a difference to patient care.

In pancreatic cancer, time is critical. A North American trial, led by our Dr. Jennifer Knox, shows that upfront molecular profiling may be key to seize the first-line treatment window, when the current options remain disappointing to patients. doi.org/10.1200/JCO-...

This next-generation lipid nanoparticle platform is delivering therapeutics with 30 – 50% greater efficiency than currently available technologies. Learn more about how Dr. Gang Zheng @pmresearch-uhn.bsky.social is transforming how medicine is delivered ⬇️

🎉Congratulations to Dr. David Kirsch on receiving the 2025 Nobility in Science Award from The Sarcoma Foundation of America (SFA), for his groundbreaking research into bone and soft tissue sarcomas, his leadership in clinical trials, and his mentorship of the next generation of cancer researchers!

Our study found that, in early-stage lung cancer, smoking status can have a greater impact on survival outcomes than some traditional staging factors, led by our Clinician Investigator Dr. Lawson Eng and an international team of researchers. doi.org/10.1016/j.jt...

#ICYMI Congratulations to @uhn.ca’s Drs. Cheryl Arrowsmith and John Dick for receiving the Awards for Excellence in Cancer Research from the Canadian Cancer Society! Read more on their research and awards ➡️ www.uhnresearch.ca/news/recogni...

📢 New research from @pmresearch-uhn.bsky.social reveals that TERT expression—even without mutations—may signal more aggressive #meningiomas than grading suggests. Challenging the current grading system, these findings could reshape how we treat these tumours. 🔗: www.uhnresearch.ca/news/better-...

Congratulations to our Senior Scientists Dr. Cheryl Arrowsmith and Dr. John Dick for receiving the Awards for Excellence in Cancer Research from Canadian Cancer Society! @uhnresearch.ca @uhn.ca cancer.ca/en/research/...

For his role in shaping the Canadian #cancer #research landscape, Dr John Dick has been awarded the 2024 Lifetime Contribution Prize. Dr Dick’s accomplishments include discovering the cells that give rise to leukemia, learning how these cells turn cancerous and developing new ways to treat cancer.

For her achievements in biomedical #cancer #research, Dr Cheryl Arrowsmith is the 2024 Robert L. Noble Prize awardee. Dr Arrowsmith studies how certain proteins in the body interact to drive cancer. She develops ways to study these proteins & identify which ones may be good anticancer drug targets.

Last week, three UHN researchers were named Fellows of the Canadian Academy of Health Sciences. This prestigious honour recognizes excellence in academic health sciences. Congratulations once again to Drs. Laura Dawson, Natasha Leighl, and Milica Radisic! 🔗: www.uhnresearch.ca/news/excelle...

@uhn.ca @pmresearch-uhn.bsky.social

Active surveillance may be a safe choice over immediate surgery for older patients with small, low-risk thyroid cancer. Only 24% needed surgery after 6 years, discovered in a collaborative study among Toronto hospitals @uhnresearch.ca @uhn.ca: jamanetwork.com/journals/jam...

Congratulations to our clinicians Dr. Laura Dawson and Dr. Natasha Leighl for being elected to the Canadian Academy of Health Sciences as 2025 New Fellows🎉. cahs-acss.ca/wp-content/u...

The identification of a unique gamma delta T-cell receptor offers a promising new approach to cancer #immunotherapy with greater precision and safety. Learn more about how Dr. Pamela Ohashi @pmresearch-uhn.bsky.social is expanding the reach and impact of immune-based cancer therapies ⬇️

Researchers developed a new molecule that binds to DCAF1, a protein linked to cancer growth and viral infection, opening new doors for cancer and HIV treatments. Developed by our Affiliate Scientist Dr. Levon Halabelian with the SGC & @oicr.on.ca. doi.org/10.1038/s420... @uhnresearch.ca @uhn.ca

🎉Congratulations to Dr. Natasha Leighl, our Head of Division of Medical Oncology and Hematology, and Clinician Investigator for receiving the ESMO Women for Oncology Award! @uhn.ca @uhnresearch.ca

🔬 New study found, in some head and neck cancers, losing one copy of the KEAP1 gene boosts NRF2 activity, which helps tumours become resistant to radiotherapy. Led by our Senior Scientist Dr. David Kirsch. Published in Cancer Clinical Research, @aacrjournals.bsky.social: doi.org/10.1158/1078...

New publication alert! 🚨 A team at @uhn.ca's @pmresearch-uhn.bsky.social explored #computationalmethods for analyzing CUT&RUN #genomic data, offering insights to improve this new, powerful technique for studying protein-DNA interactions. 🔗 doi.org/10.1093/bioi...

Thankyou for hosting us! We are so impressed by the quality of the science, collaboration and facilities at @pmresearch-uhn.bsky.social. Looking forward to developing exciting new projects together

🇨🇦🇦🇺 Thank you to @garvaninstitute.bsky.social for joining us at the Allan Slaight Breakthrough Forum! Scientists were brought together to tackle tumour complexity for translational impact. Together, we’re accelerating the path toward more precise and effective cancer care.💙

✨Explore the licensing and co-development opportunities based on our discoveries!

Scientists at @pmresearch-uhn.bsky.social have developed CellNEST, a powerful AI tool that maps how cells talk to each other. By detecting complex signals between cells, it could lead to new ways to target tumours and stop disease progression. 🔗 www.uhnresearch.ca/news/pinpoin...

🌞RMP’s exciting Summer Series is underway! This year’s theme is Advances in Radiotherapy. Join us through August 21st to hear from global leaders in the field. 🌍💡 Catch up on past sessions here under “RMP Summer Series”: pmcancercampus.ca #RadOnc #Radiotherapy @pmresearch-uhn.bsky.social

1/4 Last week was an exciting one for @pmresearch-uhn.bsky.social's CDI program at the AACR conference! This year’s focus: The transformative role of AI in oncology—from imaging innovations to foundation models shaping the future of #precisiononcology @theaacr.bsky.social #AACRai25

Congratulations to the 18 research teams at UHN's Princess Margaret Cancer Centre who secured Project Grant funding from Canadian Institutes of Health Research! We are grateful for this support—together, we’re advancing discoveries that bring us closer to a world without the fear of cancer.

A real-world study validates the LSC17 score's ability to predict AML patient outcomes and identify high-risk patients who may benefit from more aggressive treatments, led by Drs. Jean Wang @uhn.ca, Tracy Murphy & Stanley Ng. doi.org/10.3324/haem... @uhnresearch.ca

Most #cancer cells aren’t able to propagate tumours—but a rare few can. Using genetic barcodes, a team @pmresearch-uhn.bsky.social tracked these rare clones—revealing how they evolve, adapt, and resist treatment. A step toward more targeted cancer therapies. 🔗: www.uhnresearch.ca/news/rare-ca...

Congratulations to all those honored at the 14th Annual PM Research Retreat! The theme for 2025 was "It takes two to think", aiming to build collaborations among scientists and clinicians. Check out our 2025 research awardees and Papers of the Year here: www.uhn.ca/corporate/Ne...

A switch between blood cancers🩸 Study found “multipotent” cancer cells can switch cell lineages, leading to a higher risk of drug resistance and worse outcomes. A discovery led by our Senior Scientist Dr. John Dick & Dr. Charles Mullighan at St. Jude Children’s Research Hospital.

🔬 New strategy to boost immunotherapy for small cell lung cancer (SCLC): Combining PARP inhibitors + radiotherapy activates immune pathways & boosts T cell-attracting chemokines, discovered by Dr. Ben Lok’s team at @uhn.ca. Read in Nature Communications: www.nature.com/articles/s41...