Thanksgiving is always a time 4 me 2 reflect what it is 2 be Canadian, and 2 be grateful that my family chose 🇨🇦. The freedoms & liberties we share are part of the Canadian dream, a dream built on a foundation of multiculturalism, opportunity and mutual respect. 🍁🍂🇨🇦 Happy Thanksgiving. Be thankful

September was a record-breaking month for the Network! 🎆 919 full genomic profiles and clinical data from 1,036 patients were added to our Gold Cohort, the biggest monthly jump ever! This brings our total number of full genomes sequenced to 11,562 and of complete cases to 6,836! #FinishIt

Of the 202 Nobelists who have been awarded prizes in physics, chemistry and medicine this century, less than 70% hail from the country in which they were awarded their prize, a Nature analysis shows. go.nature.com/48UbZJp

If there really were such a thing as ‘Medbeds,’ don’t you think Fat Satan would have used them on his cankles, limp, decomposing hand, and dementia-ridden brain?

Terribly sad to watch the USA absolutely shit their pants in the Ryder Cup, but I guess that picking a team that is humiliating themselves on the international stage and failing to show any camaraderie or unity, America has picked a team that captures its 2025 spirit. Go Europe!!!!

Let's cheer the Canadian women dominating world rugby. They had to crowd source to raise the money to even get into the tournament. Nobody took them seriously. They crushed the New Zealand giants. They are going into the finals. Come on fellow Canucks - is the real miracle team. So proud.

Delighted to hear from the renowned Dr. Bishal Gyawali about Common Sense Oncology and his team’s work. Eg Common Sense Oncology principles for the design, analysis, and reporting of phase 3 randomised clinical trials www.thelancet.com/journals/lan...

Queen’s Department of Oncology Grand Rounds hears from the renowned Dr. Bishal Gyawali. Fantastic trainee-led editorial on how to meaningfully improve the success rate of phase 3 oncology trials academic.oup.com/jnci/article...

If you are concerned about what the 🍊🤡 is doing to universities, watch this

RFK Jr. rolled out that old chestnut again about how healthy Americans were in the 60’s, so here’s a fact check. In 1965: -42% of American adults smoked; it’s 11% now. -The infant morality rate was 24.7/1000; it’s 5.6/1000 now. -Overall life expectancy was 70 years; it's about 77 years now.

The amazing, inspirational and persistent legacy of Terry Fox. Recaptured in a new documentary of never before broadcast footage. Finish It, once and for all. www.theglobeandmail.com/gift/46242ee...

The pre-vaccine era was HELL for kids. We have already failed them on gun safety, we cannot fail them on the issue of vaccines. #VACCINES cause Adults!

Mayor Brandon of Chicago responds to a question from a reporter if pushing back will make things harder? “Can you imagine if my ancestors would have had the same rationale? Let’s not fight against the Confederacy. Let’s just try to get along, and maybe one day they’ll give us our freedom?”

Removing Drp1 in mouse zygotes disrupts mitochondrial distribution, spindle formation & embryo development, revealing how vital this protein is for early life. buff.ly/9GxSdBM

#ACTLeads Emma McIsaac & I met with John Whelan last week, a candidate for the upcoming provincial elections in St. John’s 😊 We have talked about cancer & cancer’s impact on our community and exchanged examples of real-life situations 1/ #NotAPartisanIssue #NewfoundlanAndLabrador #Cancer

I mentioned to a couple of people that I had a surprise waiting to be shared when Moderna got approval for its updated COVID-19 vaccine. It’s approved, and the big news??? Completely produced domestically!!!!! 🥳🤩 Approved as usual for all aged 6mo+!

Haeryfar Lab goes international!! 🌍 This week our amazing PhD candidate Nicole takes on the International Congress of Immunology in Vienna, Austria #IUIS2025 @iuis-online.bsky.social #WesternU @westernuresearch.bsky.social

Reading Murray Sinclair’s memoir last night and was struck by this passage about his concern that Donald Trump would win the 2024 election and “begin to look at attacking democracies like ours.” Sinclair died on Nov. 4, 2024. Trump was elected the next day.

🚀 MAJOR MILESTONES ACHIEVED! We're excited to announce that we've sequenced our 10,000th cancer case, a major milestone in our path towards creating Canada's largest and most complete cancer case resource! Two new institutions have also joined our Network, increasing our membership to 50!

File under: Why the US needs quality sex education in schools New survey results: 🔹️34.3% of adults respondents said they'd never heard of HPV; 🔹️37.6% didn't know there's a vaccine; 🔹️Among folks who'd heard of HPV, 70.8% didn't know it causes oral cancer &... www.medpagetoday.com/hematologyon...

Gavin Newsom’s Trump-troll-tweet last night at 7:20 PM is epic. I can’t stop laughing.😆 Here’s a tidbit - “MY ‘PERFECT MAPS’ ARE MORE BEAUTIFUL THAN ANYTHING IN TRUMP TOWER (WHICH MANY SAY SMELLS WEIRD)…” 😂🤣😂🤣😂🤣

Succinate preserves CD8+ T cell fitness to augment antitumor immunity: Immunity www.cell.com/immunity/ful...

AACR Project GENIE®, a publicly accessible cancer registry of real-world clinico-genomic data, has released its 18th public dataset. The registry now contains more than 250,000 genomic samples from over 211,000 patients. Learn more: buff.ly/Pa8Z2qF #AACRGENIE

Thrilled that our paper is in print @science.org!! *Platelets sequester cell free DNA, including free fetal and tumour-derived DNA* Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight

Impressive cell dance! Guided by a lethal mutation in PI3K that drives malignancy. Nature can be both beautiful and haunting at the same time.

What a day! Our SCRI Retreat 2025, "Improving Cancer Outcomes," was held Aug 12th with >150 participants, 60 posters, 10 flash talks, 3 keynote presentations, patient advocates, and much more! Thanks to all that shared their research findings that inspire us all! @queensuhealth.bsky.social

In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers

Transcriptional Circuitry in HGSOC: A Dynamic Three-State Model Informed by a Living Biobank of Purified Tumour Fractions https://www.biorxiv.org/content/10.1101/2025.07.18.665513v1

Frank's last post. Not surprising that it is supporting and boosting colleagues. Rest in peace, Frank. Thanks for making the world a little brighter for those who knew you.

"Texans should be disgusted with politicians who keep asking, 'How could we have known?' when scientists and activists have been warning them. For too long, our Republican leaders have been putting their hands over their ears and shouting, 'la-la-la, I can’t hear you!'”

Enjoyed this @natrevcancer.nature.com article on comparative oncology - how we can learn from other species 🐘🐋🦜🐍 about ways to prevent (& possibly treat) cancer. Both a review and a call to action for the research community. www.nature.com/articles/s41... @atjcagan.bsky.social @cmaley.bsky.social

CIHR NoR day is always rough. Nice to get discussed and some positive feedback. We put so much time and effort into grant applications, and reviewers work so hard to give them a chance. Too bad there is so little money in the pot - I remember the days when a 4.0 score was funded!

I watched @mark-carney.bsky.social Canada Day speech togday about 🇨🇦’s strengthening unity. It’s fitting he meet with Darrell Fox. @terryfoxfoundation.bsky.social’s @marathonofhope.bsky.social is unifying Canada’s cancer community to accelerate precision medicine, by Canadians, for Canadians 🇨🇦!

Much appreciated support from biotech execs and investors 🙏 www.statnews.com/2025/06/27/b...

Based on a first-in-human phase I trial in patients with metastatic melanoma, Hodi et al. reported safety and feasibility of WDVAX, a macroporous poly-lactide-coglycolide matrix polymer scaffold incorporating cytokine GM-CSF [...] bit.ly/44z7rFU  ‪@danafarber.bsky.social‬

This was absolutely my experience when I started at NIH in 2003. I was very impressed with how well run things were compared to my experiences in both academia and the private sector.

Just learned that Frank Stahl (of the Meselson and Stahl DNA replication experiment ("the most beautiful experiment in biology") died at the beginning of April, to no fanfare. Here's a lovely video of them reminiscing: www.youtube.com/watch?v=7-tn...

For some of us, every day is RET day! Thanks to my awesome alumni. You have all grown so much and reached so far!

It was as a RET-union for past and present @mulliganlab.bsky.social and some wannabes like me @sinclaircri.bsky.social last Friday. Quite an impressive scope and diversity of research contributions! 👏🎉😁

Led by Terry Fox's brother, cyclists on National Ride of Hope riding cross-Canada to raise $1 million for #cancer research. Team makes emotional stop at Thunder Bay memorial, where Terry was forced to end Marathon of Hope run. www.cbc.ca/news/canada/... @cbcnews.ca @terryfoxfoundation.bsky.social

"Innovation, Science and Economic Development Canada did not provide an interview or comment to CBC."

"Scientific Sovereignty — How Canadian scientists are coping with U.S. cuts and chaos" My MD/PhD student @kevinterleukin.bsky.social an I discuss how our work on sex differences in immune responses has been affected (start at 36:10 for us but full episode very worth while) www.cbc.ca/listen/live-...

Trump just declared war on Iran unilaterally in a direct violation of the Constitution. The Republicans in Congress will just roll over and Fox News will cover his ass.

Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis pubs.aip.org/aip/apb/arti...

Fantastic day talking drug discovery with our colleagues @oicr.on.ca hosted @sinclaircri.bsky.social