Kidneys rely on intricate designs to filter our blood. A new study from @uhn.ca's Dr. Milica Radisic shows how recreating the complex 3D surface environment of kidney cells helps lab-grown cells develop and behave more like they do in the body. 🔗 Read more: www.uhnresearch.ca/news/making-...

New research from @pmresearch-uhn.bsky.social unveils EASMS—a powerful screening method that detects molecule-protein interactions often missed by traditional methods. This could accelerate #DrugDiscovery, especially for previously “undruggable” targets. 🔗: www.uhnresearch.ca/news/new-too...

(1/7) 👩‍🔬 This #WomenInScienceDay, let's shine a spotlight on the diverse and talented women at @uhn.ca! From leading scientists to postdocs and support staff, meet six remarkable women making waves in research, paving the way for #AHealthierWorld. Learn more 🧵⬇️ #TeamUHNWomen

#ICYMI UHN received a historic $27.1M in funding from the Canadian Institute of Health Research Fall 2025 Project Grant competition. 31 @uhn.ca research teams are driving forward discoveries that will shape the future of health care across Canada. 🔗 Learn more: www.uhnresearch.ca/news/funding...

Our new study by Dr. Hansen He and Xin Xu's team reveals that a chemical tag called m6A, found on RNA molecules, can act like a switch for tumour growth. Adding this tag to a gene called CHD9 could slow prostate cancer growth in the laboratory: www.nature.com/articles/s43...

Who is most at risk for heart inflammation (pericarditis) in #lupus? 🫀 A new study from @uhn.ca's @schroeder-uhn.bsky.social reveals key patterns—highlighting earlier diagnosis and disease severity as risk factors for #pericarditis. 🔗Read more: www.uhnresearch.ca/news/how-lup...

For #WorldCancerDay, see how a @pmresearch-uhn.bsky.social team developed a gene score to predict survival in myelofibrosis—a rare blood #cancer. Led by Drs. Jessie Medeiros, Andy Zeng, Vikas Gupta, and John Dick, this could help tailor treatment decisions. 🔗: pubmed.ncbi.nlm.nih.gov/41481381/

“Keeping it hidden is dangerous. Being informed can save lives.” Driven by a family loss, Dr. Razq Hakem @uhn.ca @uhnresearch.ca embarked on a research journey to understand the biology of BRCA mutations in breast and ovarian cancer. www.youtube.com/watch?v=4yTT...

Small measurement errors can critically impact surgical outcomes. Researchers from @tier-uhn.bsky.social are evaluating an AI-based digital ruler designed to support more accurate measurement during image-guided procedures. 🔗Read more: www.uhnresearch.ca/news/ai-meas...

Our scientists at @uhn.ca Princess Margaret and BC Cancer discovered four new subtypes of Hodgkin lymphoma. One subtype with CSF2RB mutations creates an immune “shield”, but it can be reversed by JAK2 inhibitors, offering new treatment potential. aacrjournals.org/cancerdiscov...

🚨 New publication alert! Research from @uhn.ca reveals a mechanism behind why the immune system declines with age. B cells—best known for producing antibodies—play a critical role in driving the aging of T cells, fighters of infection. 🔗 Read more: www.uhnresearch.ca/news/aging-a...

Read about the latest findings from Canada’s largest #research hospital in @uhn.ca’s Research Spotlight newsletter: ▶️Psilocybin for treatment of #depression ▶️An #AI tool to analyze cardiac activity ▶️ Advancements in #Cancer immunotherapy + More 🔗: www.uhnresearch.ca/newsletter/r...

Two very different kinds of innovation were recognized through @uhn.ca’s Mission Excellence Awards: a new direction in cancer research led by Dr. Pamela Ohashi, and HALO, a solution already changing how patients are protected every day. 🔗 Read more: www.uhnresearch.ca/news/researc...

The @dkjei-uhn.bsky.social January #newsletter has been released! Read about our recent events, new stories, features, awards and publications >> bit.ly/46nnOWv @uhn.ca @uhnresearch.ca @kbi-uhn.bsky.social @schroeder-uhn.bsky.social @uoftmedicine.bsky.social

Chronic pain affects 1 in 5 Canadians. ECHO Pain is a medical education program designed to equip clinicians with the skills and support needed to provide safer, more effective care. ➡️ @kiteuhn.bsky.social researchers review 10 years of its impact: www.uhnresearch.ca/news/echos-b... #ChronicPain

Congratulations to our Senior Scientist Dr. Pamela Ohashi on being named one of the Fellows of the AACR Academy Class of 2026 🎉. www.aacr.org/about-the-aa... @theaacr.bsky.social @uhnresearch.ca @uhn.ca

New research from @kbi-uhn.bsky.social suggests #ChronicTraumaticEncephalopathy affects more than the brain. People with repeated head impacts also show signs in the spinal cord—especially with age—reshaping how we understand trauma‑related neurodegeneration. 🔗: www.uhnresearch.ca/news/cost-im...

(1/2) The Ontario Government has invested over $47M to support homegrown research across Ontario! Congratulations to @uhn.ca's Drs. Mamatha Bhat, Daniel Winer, Jennifer Campos, George Mochizuki, Kamil Uludag & J. Rafael Montenegro Burke on receiving funding from the Ontario Research Fund. 🎉

LIGAND-AI led by @thesgc.bsky.social at @uhnresearch.ca and funded by the Innovative Health Initiative (IHI) with EU-Canada support, is officially launched! My team will contribute AI expertise and will develop the AIRCHECK platform (aircheck.ai) for drug discovery. www.thesgc.org/news/ihi-pro...

A Canadian-led collaboration is leading a global initiative to transform drug discovery with #AI and #OpenScience! 🍁 @uhn.ca, @sickkidsto.bsky.social & @thesgc.bsky.social, are partnering on a $26M grant to support the LIGAND-AI Project—an international effort to advance precision medicine.⬇️

Meet Sumaiyah Rehman, a Scientific Associate at @pmresearch-uhn.bsky.social and champion for #IDEA principles at UHN. Read more about her inspiring work shepherding in better #cancer care and excellence in training, leadership, and culture. 🔗: www.uhnresearch.ca/news/sumaiya... #TeamUHN @uhn.ca

Researchers from @kbi-uhn.bsky.social are studying the potential of #psilocybin for #depression. Their early work represents an important step towards identifying whether this new drug has potential as a treatment for both mood and cognition. 🔗 Read more: www.uhnresearch.ca/news/fresh-w... @uhn.ca

The COVID-19 pandemic exposed aspects of surgical training that hinder surgical residents’ wellness. A new study from @tier-uhn.bsky.social explores these barriers and the need for more sustainable training environments. 🔗 Read more: www.uhnresearch.ca/news/surgica... @uhn.ca @jmirpub.bsky.social

A new @uhn.ca study shows that providing equipment, having minimal exclusions, and ensuring compatibility on any device can enable #RemoteManagementPrograms for #HeartFailure, like Medly, to provide more equitable access to care. 🔗 Read more: www.uhnresearch.ca/news/support...

#ICYMI Two @uhn.ca researchers, Drs. Shaf Keshavjee and Allison McGeer, were among those honoured by the Order of Canada for their work advancing research in #transplantation and #InfectiousDisease worldwide. 🎖️🍁 🔗 Read more: www.uhnresearch.ca/news/nationa... #OrderofCanada

A study led by Dr. Sushant Kumar @uhn.ca @uhnresearch.ca investigated structural variants—large-scale DNA changes involving over 50 base pairs—and uncovered new insights into how they arise and their links to diseases like cancers and neurological disorders. doi.org/10.1093/nar/...

Researchers at @uhn.ca’s @pmresearch-uhn.bsky.social have found that inactivation of the TET2 gene can improve #cancer immunotherapy response—opening the door for more personalized treatment strategies. 🔗 Read more: www.uhnresearch.ca/news/linking... -- @uoftmedicine.bsky.social

A collaborative @kbi-uhn.bsky.social & @uoftmedicine.bsky.social team has identified a biomarker linked to the inflammation that drives progressive #MultipleSclerosis. This is a step toward more precise diagnosis & treatment. 🔗️https://www.uhnresearch.ca/news/new-clues-multiple-sclerosis

(1/3) 🎉 Congratulations to @uhn.ca researchers Drs. Shaf Keshavjee and Allison McGeer on their appointments to the Order of Canada! Their work has advanced research in #transplantation and #InfectiousDisease worldwide. 🔗 Read the full press release: gg.ca/en/media/new...

As 2025 comes to a close, we look forward to a new year full of opportunities to continue creating #AHealthierWorld. Happy holidays from @uhnresearch.ca!

A @uhn.ca study reveals gaps in #HepatitisC care for pregnant people. Fewer than 10% of patients began treatment within 5 years of diagnosis, and many had multiple pregnancies before treatment. This highlights the need for stronger linkage-to-care. 🔗 Read more: doi.org/10.1093/cid/...

New publication alert! @uhn.ca's Dr. Viswanathan leads international experts on #MesenchymalStromalCells mechanism of action. Identifying research gaps and future directions will help boost the safety and efficacy of MSCs for conditions like #Arthritis. 🔗: www.isct-cytotherapy.org/article/S146...

🎉 Congratulations to @uhn.ca’s Dr. Sonya MacParland on receiving funding through ERDERA’s Joint Transnational Call 2025! This patient-partnered project advances research in primary sclerosing cholangitis (PSC)—a rare liver disease with no approved treatments. Learn more ⬇️

Ice remains one of winter’s biggest hazards.❄️ A new study from @kiteuhn.bsky.social finds that even top-rated winter boots do not fully prevent slips, highlighting the need for additional safety measures. 🔗 Read more: www.uhnresearch.ca/news/ice-win...

A @dkjei-uhn.bsky.social team is moving us closer to a future where blindness may not be inevitable in #RetinitisPigmentosa (RP). 👁️ In a new study, the team offer a new lab RP model and a first look at the disease’s development. 🔗 Read more: www.uhnresearch.ca/news/retinal...

Innovation in neurovascular care! Dr. Pascal Mosimann at @kbi-uhn.bsky.social has developed MagFlow, a microcatheter system that uses blood flow to navigate vessels 270% smaller than ever before. This could transform treatment for #stroke, aneurysms & more. 🔗: www.uhnresearch.ca/news/microca...

New research from @kiteuhn.bsky.social explores how adapting mindfulness practices can remove barriers for individuals with spinal cord injury, supporting psychological well-being and recovery. 🔗 Read more: www.uhnresearch.ca/news/mindful... -- @uhn.ca

Researchers from @uhn.ca have built ECG-FM, an open-source #AI model that can deliver faster, more consistent heart screening and risk assessment by interpreting electrocardiogram data. 💓 🔗 Read more: www.uhnresearch.ca/news/harness...

UHN is proud to be ranked #1 on the list of Canada’s Top 40 Research Hospitals from Research Infosource Inc. for the 15th year in a row! Thanks to our incredible research community for their continued dedication to #HealthDiscovery, #care & #education! 🔗: www.uhnresearch.ca/news/uhn-can...

A novel inhibitor, developed by Dr. Keith Stewart’s team at @uhn.ca's @pmresearch-uhn.bsky.social, successfully blocked cancer cell’s recycling system in multiple myeloma. It also shows promise for boosting anti-tumour immunity and for use in other blood malignancy. doi.org/10.1182/bloo...

Read about the latest findings from Canada’s largest #research hospital in @uhn.ca’s Research Spotlight newsletter: ▶️ Reducing heart risk in #kidney care ▶️ Hand rehabilitation with #AI ▶️ Preserving the blood-brain barrier after #stroke + More 🔗: www.uhnresearch.ca/news/researc...

A new study from @pmresearch-uhn.bsky.social shows that combining two drugs (enasidenib with venetoclax) can help people with hard-to-treat #AcuteMyeloidLeukemia achieve remission. This offers hope for longer remissions and easier outpatient care. 🔗 Read more: www.uhnresearch.ca/news/promisi...

Today the Princess Margaret Cancer Foundation announced an unprecedented donation. The $50 million gift, donated by Peter Gilgan Foundation, will establish the Peter Gilgan Centre for Early Cancer Detection Research at UHN's Princess Margaret Cancer Centre. Read more: https://bit.ly/4rochiw

From bold ideas to real-world solutions, research at UHN is ‘Driving Discovery. Delivering Impact’. 🎯 Thank you for collaborating with us as we build #AHealthierWorld for all. ➡️ Explore more in our Research Report: www.uhnresearch.ca/Research-Rep... #RR25 #DiscoveryToImpact

Celebrating our award-winning scientists whose discoveries are driving impact today and shaping the innovations of tomorrow. ➡️ Join us in honouring their remarkable achievements in health research: www.uhnresearch.ca/Research-Rep... #RR25 #DiscoveryToImpact

Could VR transform eye care? 👀 A review by Drs. Michael Reber & Lora Appel from @uhn.ca explores how immersive tech can improve accessibility and outcomes. Learn more: doi.org/10.3390/tech... #VisionCare #DigitalHealth --- @dkjei-uhn.bsky.social @kiteuhn.bsky.social

@uhn.ca's Patient Engagement in Research (@piper-uhn.bsky.social) team recently hosted its 3rd annual Research Day. Over 200 attendees explored how partnering with people with lived experience (PLEX) makes research more relevant & impactful. Read more: www.uhnresearch.ca/news/piper-r...

This year, thousands of supporters came together with the PMCF to raise funds for cancer research and care. Together, we are lighting the way forward for cancer patients and their loved ones. ➡️ Learn how we ‘Carry The Fire’: www.uhnresearch.ca/Research-Rep... #RR25 #DiscoveryToImpact

New publication alert! 🚨 @uhn.ca trainee Anthaea-Grace and Senior Scientist Dr. Antonio Strafella, together with their team, used #MachineLearning to combine neuroimaging and biofluid data—improving #Parkinson's classification accuracy. Read it in PLoS ONE ➡ journals.plos.org/plosone/arti...

Thirteen years ago, Shilpa received a double-lung transplant at @uhn.ca—made possible by an innovation funded entirely through philanthropy. This year, UHN Foundation raised $221M to support life-saving work at UHN. ➡️ Read more: www.uhnresearch.ca/Research-Rep... #RR25 #DiscoveryToImpact