Denis Chrétien
@dchretien.bsky.social
📤 433
📥 1023
📝 49
Microtubule and cryo-ET addict!
Microtubules: from atoms to complex systems
www.embl.org/about/info/c...
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Microtubules: from atoms to complex systems
https://www.embl.org/about/info/course-and-conference-office/events/ees26-09/
8 days ago
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Denis Chrétien
BioCytoLab
12 days ago
Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳 We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice. Congratulations
@subhambiswas.bsky.social
!
www.nature.com/articles/s41...
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Pilhofer Lab 🦠❄️🔬
13 days ago
Story on our Asgard microtubule paper by Nikki Greenwood:
www.quantamagazine.org/tiny-tubes-r...
Thanks to all interviewees🎤
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Tiny Tubes Reveal Clues to the Evolution of Complex Life | Quanta Magazine
Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons.
https://www.quantamagazine.org/tiny-tubes-reveal-clues-to-the-evolution-of-complex-life-20250908/
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Denis Chrétien
Institut Jacques Monod
13 days ago
📣 Paris Cytoskeleton day 2025 - Registrations are open! 📆 November 14th 📍 Institut Jacques Monod 🔗
pcd2025.sciencesconf.org
Abstract submission closes on 19 October Registration closes on 7 November
@romet-jegou-lab.bsky.social
@upcite.bsky.social
@cnrs-idf-villejuif.bsky.social
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Gautam Dey
about 2 months ago
Want to acquire
#ExM
images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
With
@dudinlab.bsky.social
@embl.org
@biology-unige.bsky.social
@moorefound.bsky.social
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MRC Laboratory of Molecular Biology
about 2 months ago
The LMB recently hosted a symposium to mark 50 years since Richard Henderson and Nigel Unwin published the structure of bacteriorhodopsin, the first 3D structure of a protein determined by
#cryoEM
. Read about the event and find more photos here:
www2.mrc-lmb.cam.ac.uk/the-structur...
#LMBNews
🧪🔬
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Kat Toropova
about 2 months ago
Thrilled to see our study on how kinesin-2 motors are switched on and off published in
@natsmb.nature.com
⚛️ ➡️
www.nature.com/articles/s41...
Congrats to all authors from me and Anthony 🎉
@dunnschool.bsky.social
Check out this animation made by talented PhD student
@matthew-batisio.bsky.social
😆
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Josh Dickerson
3 months ago
Check out our recent review discussing the merits of tilt series vs single micrographs for in situ cryo-EM!
www.sciencedirect.com/science/arti...
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To tilt or not to tilt? Strategies for in situ cryo-EM data collection
Recent breakthroughs in single-particle cryogenic electron microscopy (cryo-EM) and protein structure prediction have transformed our ability to resol…
https://www.sciencedirect.com/science/article/pii/S0959440X25001186
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Florian Wollweber
3 months ago
After 5 amazing years
@pilhoferlab.bsky.social
I'm starting my lab
@embl.org
Grenoble this November
embl.org/wollweber
We'll image Asgard archaea and many other strange microbes (
#archaeasky
,
#protistsonsky
..) to understand eukaryogenesis First job ad:
#teamtomo
scientist!🔬❄️
tinyurl.com/2rdu2ze6
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Bettina Böttcher
3 months ago
Our paper on Lymphostatin is now out (
rdcu.be/etk2v
). It shows
#cryoEM
structures of this huge virulence factor revealing amazing domain reorganisations. Very enjoyable collaborating with the Stevens Lab in Edinburgh and the Boersch Lab in Jena to see how it gets into cells.
@uni-wuerzburg.de
🧪❄️
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Denis Chrétien
Paul & Virginie - Centriole Lab
3 months ago
🚨 New preprint! Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with
@cellarchlab.com
@chgenoud.bsky.social
@stearnslab.bsky.social
🙌.
#TeamTomo
#UExM
www.biorxiv.org/content/10.1...
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Denis Chrétien
A/Prof Sam Stehbens PhD (She/Her)
11 months ago
it never gets old......
#microtubule
dynamics - the fireworks of EB comets
#microscopy
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Beautiful 😍
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3 months ago
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Dual-axis cryo-ET on cryo-FIB milled lamella 🙂
www.researchsquare.com/article/rs-6...
#CryoEM
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On-lamella dual-axis cryo-electron tomography and modelling of lamella stability
Cryogenic electron tomography (cryo-ET) of cryogenic focused ion beam (cryo-FIB) milled lamellae enables the study of 3D cellular architecture in near-native conditions at nanometer-scale resolution. ...
https://www.researchsquare.com/article/rs-6497420/v1
4 months ago
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Denis Chrétien
European Research Council (ERC)
4 months ago
🎉 Congratulations to Wolfgang Baumeister
@maxplanck.de
, awarded the 2025
#ShawPrize
in Life Science & Medicine for pioneering work in cryo-ET! Learn more 👉
europa.eu/!JBXDBG
#FrontierResearch
#ERCSyG
#CryoET
#StructuralBiology
#shawprize2025
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ERC grantee wins the Shaw Prize in Life Science and Medicine
2025 Shaw Prize honours ERC-funded research in molecular imaging
https://europa.eu/!JBXDBG
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Denis Chrétien
Institut Pasteur | 130 years of biomedical research
4 months ago
Zoom into a human cell infected by Shigella, the bacteria behind dysentery. Using cryo-EM,
@leaswistak.bsky.social
and team revealed how it pierces cells with molecular syringes. Stunning science at the nanoscale.
@enningalab.bsky.social
@jytinevez.bsky.social
@nanoimaging.bsky.social
#CryoEM
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Philippe Van der Stappen
5 months ago
Hey
#TeamTomo
, Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging? That's why
@florentwaltz.bsky.social
and I made this website!
tomoguide.github.io
Follow the thread 1 /🧵
#CryoET
#CryoEM
🔬🧪
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Welcome to TomoGuide
A step-by-step Cryo-ET guide
https://tomoguide.github.io/
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Denis Chrétien
Marine Biological Laboratory
5 months ago
It's
#MicroscopyMonday
, so let's take a peek into the 🔬 This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time. Dr. Inuoe premiered his research at MBL.
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Alexis Verger 🧬🧫🧪
5 months ago
Choose Europe (France) for Science
#ESR
(credit : Jérôme Sié)
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Romain Gibeaux
5 months ago
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Romain Gibeaux
5 months ago
WOSM-TIRF up running! Awesome
#Tirf
imaging of microtubules and EB comets in
#Xenopus
egg extract. The WOSM-TIRF is the big brother of the eduWOSM (
doi.org/10.7554/eLife.104046.1
). So grateful to
@irobcross.bsky.social
& Nick Carter for this collaboration &
@agencerecherche.bsky.social
for funding.
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Denis Chrétien
JEOL EUROPE
5 months ago
#JEOL
CRYO ARM™ 200
#CryoEM
installed at the Institute Genetics & Development of Rennes. First installation of this type of instrument in France and incorporates the latest technologies in cryo contrast enhancement and dual-axis
#tomography
. We wish IGDR success with their future research projects.
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First images coming soon 🤩
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5 months ago
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So beautiful 😍
6 months ago
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Jeff Aurand
6 months ago
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Denis Chrétien
NanoImaging Services
6 months ago
The third and final chapter of our webinar series “Cryo-EM: Back to Basics” is on demand. Hear from Giovanna about challenges in
#cryoEM
, how to overcome them. Catch all three chapters: Chapter 1:
youtu.be/e8GyDe4_BAQ
Chapter 2:
youtu.be/2dBnPVkaoFs
Chapter 3:
youtu.be/kUGNSTGc8II
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Cryo-EM: Back to Basics - Chapter 1
Rediscover the fundamentals of cryo-EM with NIS CSO, Giovanna Scapin! Join us for three engaging sessions covering Sample Preparation & Imaging, Data Process...
https://youtu.be/e8GyDe4_BAQ
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Denis Chrétien
Joachim Frank
6 months ago
regarding Columbia University, I just learned about this (anonymous) account of negotiations of the Hitler regime in the 1930s with Frankfurt University -- Germany's most prestigious university at the time:
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Denis Chrétien
Pilhofer Lab 🦠❄️🔬
6 months ago
Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper
www.cell.com/cell/fulltex...
by
@xujwet.bsky.social
&
@florianwollweber.bsky.social
, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules!
#TeamTomo
#ArchaeaSky
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Denis Chrétien
Eric Lagadec
7 months ago
Revivez les dernières secondes de l'alunissage de la sonde Blue Ghost dimanche dernier!
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Joachim Frank
6 months ago
This is just wonderful
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Denis Chrétien
Institut de Génétique & Développement de Rennes
7 months ago
📢 Are you planning to do a
#PhD
in
#Biology
? Do not miss our call for
#IGDR
PhD Program Apply before April 21st, 1:00 pm 4 to 8 positions available ℹ️https://igdr.univ-rennes.fr/en/application-igdr-phd-program cc
@cnrs-bretagneloire.bsky.social
@insermgrandouest.bsky.social
@rennesuniv.bsky.social
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Denis Chrétien
Institut de Génétique & Développement de Rennes
6 months ago
IGDR Keynote Lectures | Pr. Gabriel Waksman
#Science
#Biology
#Health
Structural and Molecular Biology of Bacterial Conjugation 📅 Thursday, April 3 🕒 11:00 AM 📍 Amphi A ℹ️
openagenda.com/fr/igdr-inst...
cc
@cnrs-bretagneloire.bsky.social
@insermgrandouest.bsky.social
@rennesuniv.bsky.social
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Scrat (JEOL ARM 200) is now installed in Rennes with a Direct Electron Apollo camera. Don't hesitate to get in touch if you need nice SPA or cryo-electron tomography (single and dual axis) data 😍
biosit.univ-rennes.fr/en/tem2c
#CryoEM
6 months ago
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Denis Chrétien
Joachim Frank
7 months ago
I think it's important to reach out to your own community and explain what the funding cuts mean in practice.
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Manuel Thery
7 months ago
Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required. Please Repost 🙏 thanks !
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Denis Chrétien
laydgeur
7 months ago
Je pense qu’ici je prêche des convaincus, mais ce rappel est toujours bon, parce que je ne comprends toujours pas pourquoi nos politiques et officiels utilisent encore cette plate-forme de propagande hostile à la France pour leur communication… ça me dépasse.
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Greg Madej
7 months ago
the cryo-clipping-box for JEOL cryoARM... easy!
#cryoEM
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Eric Lagadec
7 months ago
Ces gens se battent contre les faits, contre les connaissances... Et ils sont puissants. Il va falloir qu'on se batte aussi, et qu'on continue le travail de diffusion et de vulgarisation des sciences. Ce monde devient fou...
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Andreas Prokop
7 months ago
See also Pearce et al., 2018, Bull Math Biol 80, 3002ff. --
doi.org/10.1007/s115...
Ziebert et al., 2015, Phys Rev Lett 114, 148101ff. --
doi.org/10.1103/Phys...
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Denis Chrétien
Kevin Terretaz
7 months ago
happy valentine's
#FluorescenceFriday
💙❤️💚
#microscopy
#SciArt
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Denis Chrétien
Alex McDougall
7 months ago
Microtubules still doing their thing in an early ascidian embryo (Phallusia). Thanks to the Ascidian BioCell Team
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Christophe 🔬 L
7 months ago
The N-SIM scope got its annual visit at
@ncis-marseille.bsky.social
and it's ready to deliver! Projected 3D-SIM stack of a COS cell labeled for actin ⚪ microtubules 🔵 and clathrin 🟠
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Denis Chrétien
STCmicrobeblog
8 months ago
@stevestuwill.bsky.social
you posted on 𝕏 on Dec 5, 2020 this stunning video - why not repeat on 🔵bsky ? (sorry, I did)... "Time-lapse footage of a vampire amoeba: a microscopic organism that feeds on algal cells by breaking through their cell walls and sucking out their insides."
#ProtistsOnSky
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Christophe 🔬 L
8 months ago
Reminder that
@europepmc.org
is a mirror of Pubmed with better search and that it indexes *all* bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed
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Libération
8 months ago
⚫ So long Marianne Figure emblématique de la pop britannique, Marianne Faithfull est morte à l’âge de 78 ans C'est la une de
@liberation.fr
ce vendredi
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8 months ago
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Christophe 🔬 L
8 months ago
🙌
www.aefinfo.fr/depeche/7248...
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Denis Chrétien
Laura B. Richardson
8 months ago
Creepy crawlies! But not worms or snakes—microtubules!
@zaniclab.bsky.social
#FluorescenceFriday
#microtubules
#cytoskeleton
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Anna Cassidy
8 months ago
Happy
#FluorescenceFriday
! I've always been inspired by the intersection of art and science. This microscopy image collage, inspired by Andy Warhol, highlights the beauty of cells 🔬
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Denis Chrétien
Rémi Fronzes
8 months ago
go.bsky.app/CuUhpYV
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