Benoît Zuber (@benoitzuber.bsky.social)

New paper in Nature Communications: we identified ANTXR2 (CMG2) as the cellular receptor for C. perfringens NetF toxin, causing hemorrhagic enteritis in dogs and foals. ANTXR2 was previously known as the receptor for anthrax toxin PA. doi.org/10.1038/s414...

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Identification and structural characterization of anthrax toxin receptor 2 as the Clostridium perfringens NetF receptor - Nature Communications This study identifies ANTXR2 as the cellular receptor for Clostridium perfringens toxin NetF and determines its structure bound to the toxin using cryo-EM, revealing a distinct lateral binding mechani... https://doi.org/10.1038/s41467-026-69526-6