1/8 How can the brain create countless unique memories using a single, universal metric of space? We’ve been waiting for the answer to this for two decades! Read it here: www.biorxiv.org/content/10.1...

(edited repost) Thrilled to see our computational work on adaptive shaping of behavior (we call it outcome-based curriculum learning) in PLoS Comp Biol! @wl-tong.bsky.social, @gautamreddy.bsky.social & I formalize curricula in any RL task that can be framed as sequential simple-to-complex behavior.

🧪In a post for the SciELO in Perspective blog, Jordan F. Sampar e Lilian N. Calò present the @prelights.bsky.social preprint server, formed by young researchers to evaluate preprints and post comments online, which function as post-publication peer review. blog.scielo.org/en/2025/09/1...

In this month’s “Liftoff,” @matthiasnau.bsky.social talks about the importance of making quick decisions as a PI, and @kmcostalab.com shares how lab members being mad at a PI can sometimes be a good thing. By @franciscorr25.bsky.social #neuroskyence www.thetransmitter.org/liftoff-new-...

Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain https://www.biorxiv.org/content/10.1101/2025.09.15.675867v1

Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information: 🔗 doi.org/10.1101/2025...

Beyond Locomotion: How Specialized Motor Rhythms Enable Vertebrate Escape from Capture https://www.biorxiv.org/content/10.1101/2025.09.08.674955v1

(4/8) Beyond neural predictions, POCO's learned unit embeddings independently reproduce brain region clustering without any anatomical labels. That means at single-cell resolution across entire brains, POCO mimics biological organization purely from neural activity patterns ✨

(1/8) New paper from our team! Yu Duan & Hamza Chaudhry introduce POCO, a tool for predicting brain activity at the cellular & network level during spontaneous behavior. Find out how we built POCO & how it changes neurobehavioral research 👇 arxiv.org/abs/2506.14957

Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1...

Nemo needs gap junctions, too. New preprint with Marleen Klann, Vincent Laudet, et al. showing anemonefish Snowflake mutant due to E42K substitution in Connexin Gja5b. Found exact same E42K in zebrafish gja5b (= leopard) by ENU, to the nucleotide! Details, inferences: www.biorxiv.org/content/10.1...

I am thrilled to share the main result of our work at @nordenlab.bsky.social with @liormoneta.bsky.social and @carldmodes.bsky.social . We bridged DevBiology + theoretical physics to understand how the eye becomes round #morphogenesis #devbio #biophysics #zebrafish www.biorxiv.org/content/10.1...

🐟 Autism, genes and setting Zebrafish with an autism-linked mutation acted less social in a stressful Styrofoam tank but less so in clear Plexiglass. This shows how environment can shape social behaviour in genetically predisposed animals. 🔗 www.eurekalert.org/news-release... #SciComm 🧪

Extremely proud to have contributed to this monumental effort of recording the entire mouse brain, at cellular resolution, during complex behavior 🧠🐭

The mouse brain lights up during decision making, showing widespread activity across both predictable as well as unexpected areas. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/decision-mak...

First sneak peek into SimFish! 🐟 Long in development with @isaacbianco.bsky.social and Sam Pink, our fish-on-chips now captures key aspects of larval #zebrafish sensory processing and motor control.

Great story in the @thetransmitter.bsky.social today by @callimcflurry.bsky.social. It was fun chatting about @melcooperphd.bsky.social's new research on astrocyte networks. Read the story here: www.thetransmitter.org/astrocytes/a... Read the preprint here: www.biorxiv.org/content/10.1...

Zebrafish sleep displays distinct sub-states https://www.biorxiv.org/content/10.1101/2025.08.28.672887v1

Now published @natecoevo.nature.com with @annika-nichols.bsky.social, our latest on the evolution of 𝘴𝘭𝘦𝘦𝘱 across 𝟲𝟬 𝘀𝗽𝗲𝗰𝗶𝗲𝘀 of cichlid fishes! doi.org/10.1038/s415... with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social

We look forward to hosting you in Singapore 🇸🇬 Beyond the science, there will be great food, opportunities for sightseeing, and a unique banquet experience! ❤️🐟 Feel free to approach us for more details! @oehlerslab.org @shifengxue.bsky.social Ajay Mathuru Sudipto Roy Yan Chuan etc

How do brains make decisions when faced with multiple, potentially conflicting cues? In our latest preprint, we show how #zebrafish use an additive strategy and process multiple visual features through anatomically distinct parallel pathways tinyurl.com/mvkn8em9 Thread 👇

This is fucking amazing.

Latest from the lab. Beautiful work from Joanna Lau and a fantastic collaboration with James Fitzgerald. www.cell.com/current-biol...

Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing. www.biorxiv.org/content/10.1...

#FocalPlaneFeatures meets @prelights.bsky.social @fadelvalle.bsky.social & Vibha Singh have picked 2 fantastic #cellbio preprints & will be presenting their preLights alongside research talks from @probablycarmen.bsky.social & Eva Mejia-Ramirez. Register: focalplane.biologists.com/2025/08/20/f...

Why would anyone want to be a scientist? Check out our new Essay from Martin Schwartz: journals.biologists.com/jcs/article/...

"Some might argue that personal growth is a fine thing, but not enough to justify the investment that goes to support educating a scientist. Rather, we'd argue that our current focus on professionalization runs the risk of homogenizing science, to its detriment...Science is done by whole people."

New idtracker.ai: rethinking multi-animal tracking as a representation learning problem to increase accuracy and reduce tracking times elifesciences.org/reviewed-pre...

Is @zebrafishrock.bsky.social slack group working for everyone? @mads100tist.bsky.social

The creative process in science has a set of thinking tools that we could do a better job teaching. Here are the 12 articles that Martin and I wrote about them, including "It takes two to think", "A hypothesis is a liability" and "The two languages of science". night-science.org/home/learn/r...

Excellent paper from @emreyaksi.bsky.social @manumameli.bsky.social labs. So much gold in the supplementary figures! www.nature.com/articles/s42...

Predicting individual learning trajectories in zebrafish via the free-energy principle www.biorxiv.org/content/10.1...

Our preprint is out: following up on our previous work on the zebrafish lateral hypothalamus, we do a deep dive into the molecular identities of #zebrafish LH cell types and compare them to mice. We found a novel conserved population expressing the growth hormone receptor, read to find out more!

Coming March 17, 2026! Just got my advance copy of Emergence — a memoir about growing up in group homes and somehow ending up in neuroscience and AI. It’s personal, it’s scientific, and it’s been a wild thing to write. Grateful and excited to share it soon.

How is the nervous system organized to coordinate behavior? To approach this massive question, a team led by @asbates.bsky.social, @jasper-tms.bsky.social, @mindyisminsu.bsky.social, & Helen Yang present the BANC: a Brain and Nerve Cord connectome. Preprint: doi.org/10.1101/2025... 🧪#Neuroskyence

Cool astrocyte paper!

Finally it's out! www.nature.com/articles/s41... How flexible are essential innate behaviours and their underlying neural circuits? @felixbaier.bsky.social & I, with Hopi Hoekstra and @farrowlab.bsky.social, addressed this by studying the #evolution of threat avoidance in Peromyscus mice.

I just wrapped up an amazing summer at RIKEN’s Center for Brain Science and University of Tokyo (IRCN‐Chen Institute Joint Course on Neuro‐inspired Computation) in Tokyo, where I presented my poster and had countless inspiring scientific conversations! 🧠

Using high-speed video and neural networks, researchers have compared hunting behaviours across five species of larval fish. The study uncovers both shared strategies and striking differences in how fish move, see, and strike during prey capture. buff.ly/T2o9JJp #EvoBio

I found Neuromatch's coursebooks helpful. Here's the Comp NeuroSci one: compneuro.neuromatch.io Here's the NeuroAI one: neuroai.neuromatch.io AND! @incforg.bsky.social has some solid study tracks. From CN basics to something like neuroinformatics: Here's the link: training.incf.org/study-tracks

Let's share @etlunsford.bsky.social's work : to survive, animals avoid drifting involuntarily in their environment. While humans rely on visual & vestibular cues, birds & fish need to sense complex flow changes of the external fluid (air/water) around them to select motor actions. How do they do?(1)

Latest from my lab: we identify and characterize the function of binocular neurons zebrafish larvae use to hunt prey; sciencedirect.com/science/arti.... Congrats to Richard Tian, Gewei Yan and Tommy Lam @tkclam.bsky.social!

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇

High throughput machine learning pipeline to characterize larval zebrafish motor behavior. @Horstick_Lab. www.biorxiv.org/content/10.1...

“We found that inter-species differences in noise levels & their theoretically predicted impacts on visual sensitivity are qualitatively consistent w/ our experimentally observed differences in saccadic suppression strength between the fish & the monkeys.” New work from @arrenberglab.bsky.social 🔥

A connectomic resource for neural cataloguing and circuit dissection of the larval zebrafish brain. New preprint from Engert Lab www.biorxiv.org/content/10.1...

It's SO important to comment your code. Not for any good reason, just to give yourself a chuckle two years down the track. I'd probably use the same solution today.

“We suggest that zebrafish phototaxis is regulated via parallel processing streams, which could be a universal implementation to change strategies depending on developmental stage, context, or internal state, making behavior flexible and goal-oriented.” New work from @zwitscherarmin.bsky.social 🐟

This is one of the prettiest things I have seen in a long time :)