Please share! The USC Department of Quantitative and Computational Biology is searching for a full-time, teaching-track faculty member for the teaching of QBIO undergraduate statistics and computational biology courses. usccareers.usc.edu/job/los-ange...

We got a new lab photo! Celebrating a productive year - 3 upcoming preprints (keep an eye out!) 2 trainee grant submissions and 1 master's thesis - with axes and knives throwing. I'm very proud of my group and I'm darn lucky to have them working with me! #ProudPI

“South America—the last continet to be settled—was peopled in surprisingly complex way” by Lizzie Wade @science.org www.science.org/content/arti... (Link to the paper in the quoted skeet below)

Anne C. Stone, Regents Professor @arizonastateuni.bsky.social has been awarded our Lifetime Contribution Award. @acstone.bsky.social Visit our website to learn more about the SMBE Faculty Awards 🔗 smbe.org/faculty-awards #society

Our new paper is out in @nature.com! By exploring the rich genetic diversity of Indigenous peoples across America, we show how large-scale genomic data reveal far more complex evolutionary history, shaped by multiple dispersals, long-term regional continuity, and adaptation to diverse environments.

Very proud to share our new work on General, orders-of-magnitude faster whole-genome analysis with genotype representation graphs (GRG). We topped ourselves in this one 🚀 and made GRG a practical foundation for biobank-scale population and statistical genetics. www.biorxiv.org/content/10.6...

📢 Call for submissions: The RECOMB-Genetics satellite workshop will take place in Thessaloniki, Greece 🇬🇷 on May 25, 2026, just before the RECOMB conference (May 26–29) @recombconf.bsky.social 📅 Submission deadline: April 2 (AoE) 👉 recomb.org/recomb2026/r... Submit your work and join us!

SMBE 2026 Workshop: Genomic History Inference Strategies Tournament (GHIST) kickoff 🗓️ June 28 🔗 smbe2026.org/programme #SMBE2026

Second- or third-year PhD student in biological or biomedical sciences? Get ready — applications for our #GilliamFellows Program open Sept. 1! Robust research support, incredible scientific community, & tailored professional development that can transform a PhD journey. 🧪 bit.ly/4bjdTmr

Leipzig U and the MPI for Evolutionary Anthropology (MPI-EVA) have an open faculty position (W2) in evolutionary population genetics! This position is tenured and comes with generous core funding. We are eager to welcome a new colleague! Deadline March 11. www.uni-leipzig.de/en/newsdetai...

The PopGen Vienna Seminar series schedule is ready for the next term (March-June). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website popgen-vienna.at/news/seminars/

Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!

Very excited about this year’s Biology of Genomes meeting, especially keynotes from @jkpritch.bsky.social and @janetk.bsky.social. A great venue to see what’s new and upcoming in genomics, writ broadly. Abstract submissions due in 1 week!

Happy to share my work with my advisor Zachary Szpiech! Why are associations between ROH & complex traits inconsistent across studies? We use realistic simulations to show how demographic history and genetic architecture interact to shape the phenotypic impact of ROH. www.biorxiv.org/content/10.6...

The registration deadline is fast approaching for probgen 2026! Abstracts due by January 15, registration by January 31 probgen2026.github.io

Grateful to share our paper on gene-specific selective sweeps in human gut microbiomes, now out in Nature! It has been a joy to work with @rwolff.bsky.social, whose insights and hard work made this possible. www.nature.com/articles/s41...

Well well. The standard model for how frequencies of recessive disease genes are established doesn't work. And that seems to be because recessive variants are visible to selection due to pleiotropy. (But still we teach Mendelian genetics...) www.biorxiv.org/content/10.6...

Preprint online right before the holidays! Excited to share the first piece of work from the Zhang Lab, led by my absolutely stellar postdoc Michelle Kim! In this work, we ask how admixture, selection and demography shape complex trait genetics and GWAS performance www.biorxiv.org/content/10.6...

Work from my amazing undergrad @leyan-wang.bsky.social is just preprinted! TL;DR: If you worry that ARG methods might fail on unphased data due to phasing errors, you may not need to. Check it out & consider reposting to support a great young scientist!

And another paper from the admixlab: SAI - statistics for adaptive introgression! doi.org/10.1093/molb...

I am thrilled to share this paper outlining some ideas I’ve been thinking about for a little while on a simple but powerful approach for predicting risk of inbreeding depression from long runs of homozygosity and non-ROH heterozygosity. 1/n @klohmueller.bsky.social doi.org/10.1016/j.tr...

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

Sophie Buysse's paper on short stamen loss in Arabipsis is published in this month's Evolution issue!! academic.oup.com/evolut/artic... @journal-evo.bsky.social

Having major FOMO about #SMBE2025 in my hometown… but I’m very proud that my postdoc, Susanna Gutierrez, will be presenting our work on inferring the selection history of adaptive introgression candidates in Peruvians at poster S12-P19. Please visit her during poster session 3 if you're interested!

The preliminary program of ProbGen 2026, which will be held at UC Berkeley, is now up: probgen2026.github.io Sharing on behalf of Rasmus Nielsen who is not on this site. For more see his thread on that other site: x.com/ras_nielsen/...

Super excited to share my latest preprint with @klohmueller.bsky.social! Here we leverage the unique signature that recessive deleterious variants can lead to an increase in archaic ancestry to tackle a classic question - the dominance distribution on the human genome www.biorxiv.org/content/10.1...

Repost w/ correct link! The Dept of Human Genetics at the Univeristy of Utah is hosting a Rising Stars in Genetics & Genomics postdoc symposium. We are looking to feature postdocs doing cool science! Please self nominate or nominate an excellent postdoc! #ASHGtrainees docs.google.com/forms/d/e/1F...

Kirk Lohmueller DominL uses patterns of archaic ancestry to infer degree of dominance. Provides statistical support for the presence of recessive deleterious mutations in the human genome. Up to 15% of the human genome may carry recessive deleterious mutations! 🧬 #HumanEvo25

a quick note on my paper with @jeffspence.bsky.social and @jkpritch.bsky.social on conditional frequency spectra, now out in a @genetics-gsa.bsky.social special issue: doi.org/10.1093/genetics/iyae210

Excited to share: "Addressing missing context in regulatory variation across primate evolution" arxiv.org/abs/2504.02081

A really nice paper by @drghawkes.bsky.social et al. argues that rare and common genetic associations converge on the same genes. While this seems at odds with our recent work about how burden tests and GWAS prioritize different genes, our results agree (🧬🧪🧵 1/6) www.biorxiv.org/content/10.1...

Really excited to see this work, led by Mike Grundler, published! It's a new method for inferring the geographic locations of shared genetic ancestors. In the paper, we and use it to infer the geographic history of human genetic ancestry www.science.org/doi/10.1126/...

Grundler et al propose a new method to infer the geographic position of all our genetic ancestors www.science.org/doi/10.1126/... building on a method by Wohns et al www.science.org/doi/10.1126/.... My thoughts on the approach: www.science.org/doi/epdf/10.....

Think of a polygenic score you care about. Are direct genetic effects driving variation among people in this predictor? Or perhaps other, confounding factors? We at the @arbelharpak.bsky.social & @docedge.bsky.social Labs developed a method to tackle this question. [1/n]

We are thrilled to share that our paper entitled "Inference of the demographic histories and selective effects of human gut commensal microbiota over the course of human history" is officially out in MBE! academic.oup.com/mbe/advance-...

Thrilled to have been a part of this study led by @aidaandres.bsky.social that finds evidence of genetic adaptation in chimpanzees to different habitats. Most notably signatures of positive selection in chimpanzees underlie resistance to malaria in humans (GYPA and HBB).