Proud to present our new paper in @natmetabolism.nature.com The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases lnkd.in/eVzFrmUY Check out our open-access platform chock-full with iPSC- and 🧠 lipidomics data (www.neurolipidatlas.com).

VPS13A & VPS13C are lipid transport proteins linked to #ChoreaAcanthocytosis & #ParkinsonsDisease. @pengxu.bsky.social @pdc-lab.bsky.social &co shows that mice lacking either protein are viable but absence of both results in defective #hematopoiesis & lethality @plosbiology.org 🧪 plos.io/46rTEAy

Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...

Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou

This month’s Discover ASAP episode features @danacobblewis.bsky.social talking with Miguel Gonzalez-Lozano, PhD, about EndoMap, a new open-access tool mapping the endosomal system in #Parkinsons 🗺️ 🧪 🔗 Learn how this resource accelerates discovery and supports drug development: bit.ly/4njfGfM

New paper alert! I’m very excited to share our paper published in @embojournal.org! @pdc-lab.bsky.social @yaleneuro.bsky.social

Just published: the @pdc-lab.bsky.social, led by @anbangdai.bsky.social, sheds light on the localization and function of BLTP2, a bridge-like lipid transfer protein: BLTP2 is found at contacts between the endoplasmic reticulum (ER) & plasma membrane (PM), and plays a key role in PM dynamics.

🚨 JOB ALERT! Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack Register 👇 www.cognitoforms.com/Ntu18/NTUSin...

@anbangdai.bsky.social et al. @pdc-lab.bsky.social report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain #endosomes & #macropinosomes undergoing fusion rupress.org/jcb/article/...

👏 We’re recognizing Ben Johnson (CRN Team De Camilli) as this month’s Open Science Champion! Ben developed a color-coded Open Science compliance manual that makes ASAP policies easier to navigate and apply. Thank you for raising the bar for #OpenScience, Ben! Check out the manual: bit.ly/46DuL6R

One for the Apicomplexa peeps: ever wonder how does the IMC grow so fast during progeny formation? Where do all the lipids come from? In our latest work on malaria RBC stages we implicate this monster protein (~6000 residues!) and ER contact sites. Happy+proud to share and keen to hear thoughts!

New work @harvard by Miguel Gonzalez-Lozano @harperlabhms.bsky.social & @ernstschmid.bsky.social in Johannes Walter lab charts structural interactome of endosomes. #XL-MS #Alphafold Funded by @asapresearch.parkinsonsroadmap.org & NIH. Science continues-despite attacks www.nature.com/articles/s41...

In 1️⃣ week! On May 20th, we are delighted to host Erika Holzbaur, PhD, from @pennmedicine.bsky.social, who will give the 2025 @kavliatyale.bsky.social Distinguished Lecture ✨ This event is open to all Yale affiliates, and a reception will follow.

mTORC1 is activated when cells are fed with amino acids. New preprint with @robzonculab.bsky.social led by Rachel Jansen shows how the massive "CastiGATOR" complex is formed when arginine-free CASTOR1 binds to the GATOR2 complex to antagonize mTORC1 starved cells. tinyurl.com/yr6en6f4

tinyurl.com/mrce6bbb Fun to write this N&V together with Regina @hrshin.bsky.social, on the several cryoEM papers that build on her discovery of the fascinating LYCHOS protein and its role in cholesterol sensing and mTORC1 regulation!

mScarlet3-H (aka mYongHong), a highly stable monomeric red fluorescent protein, works well for long-term super-resolution imaging, rapid tissue clearing, and CLEM www.nature.com/articles/s41...

Earlier this month I had the honor of interviewing Dr. Zoncu @robzonculab.bsky.social during his visit to Yale. It was so inspiring- and also fun! Here is a link: medicine.yale.edu/cellbio/news...

I am super excited to share our article addressing a longstanding question in neurobiology: how Ca²⁺ signaling cascades initiated at dendritic spines operate at a distance. Check it out here: authors.elsevier.com/sd/article/S... @cp-cell.bsky.social.