Mapping the heritability of disease: a nationwide study @natcomms.nature.com

Great work by the amazing Fenfen Ge on how suicide attempts and suicides have surprisingly different risk factors.

Group poster today from @jaredgm.bsky.social on genetics of perinatal depression. Jared is a DepGenAfrica postdoc - he is looking for collaborators with African PND data also. Visit poster P018.085D today at 4pm! #eshg2025

Massive multi-ancestry GWAS resource for 1,167 clinical traits & diseases in 6 global biobanks (n=1,789,365) 👉29,139 locus-trait pairs 👉2,624 non-overlapping loci across the genome 👉associated with 6 traits each (median) 👉colocalization across traits for 72% of loci [1/3]

What does it take to launch a precision health study? A bold vision, an exceptional team, a supportive ecosystem, and perseverance! We are proud to introduce the Danish Precision Health Initiative: a resource built to drive precision cardiometabolic health research for years to come. delphi.ku.dk

📢 Applications open for the SMARTbiomed Summer School! 🧠 Learn Causal Inference, Statistical Genetics & ML in R 📍 June 23–27 at the stunning Sandbjerg Estate, Denmark ⏳ Apply by April 19 — limited spots available! 👩‍🔬 For PhDs, postdocs & early-career researchers 🔗 smartbiomed.dk/news-and-eve...

Multiple Postdoc Positions available in Epidemiology, Biostatistics, or Statistical Genetics (deadline April 15) Join an International team at the Pioneer Centre for SMARTbiomed, Aarhus, Denmark! #Postdoc #Epidemiology #StatisticalGenetics #Biostatistics 👉 international.au.dk/about/profil...

I’m always happy to discuss the pros and cons of academic/neuroscience life in Denmark. Like any small European country there are some hurdles but it is overall an excellent place to be. We’re happy here.

We are seeking talented researchers for multiple postdoctoral positions in Epidemiology, Biostatistics, or Statistical Genetics at the Pioneer Centre for SMARTbiomed at Aarhus University, Denmark. international.au.dk/about/profil...

We're hiring Pioneer Fellow Postdocs!! Join us at the Pioneer Centre for SMARTbiomed to develop innovative methods in epidemiology, biostatistics, and statistical genetics, working with big biomedical data. international.au.dk/about/profil... #StatGen #Epi #Postdoc #SMARTbiomed

EMGM2025 abstract deadline extended – 09/02 (final). Conference 8-9 April, Brest, France. Everything statistical and population genetics, genetic epidemiology, bioinformatics… Invited speakers: Céline Bon, Beatriz Cuyabano, Garrett Hellenthal. emgm2025.sciencesconf.org

ESHG Abstract Deadline Reminder! The Submission Deadline for #ESHG2025 is in a week (Jan 30)! Please join us this spring (May 24-27) in Milan, Italy, for another fun and exciting ESHG conference! Learn more at 2025.eshg.org Please retweet. #Genetics #ScienceConference #ESHG #ESHG2025

Would you like to chat about all things #OpenScience in the Swiss Alps? 😆🇨🇭

Den store Danmarks Indsamling starter i dag. Jaja, man kan byde på frokost, rundvisning osv. med folketingsmedlemmer - men man kan også opleve det aarhusianske dødsmetalband Livløs sammen med folketingets eneste heavy metal-ordfører 🤘 Tak til bandet for støtten #dkpol www.lauritz.com/da/auction/k...

Kort før jul lavede regeringen sammen med SF, LA, Danmarksdemokraterne og Konservative nogle småjusteringer af den dumme, dyre og dybt skadelige kandidatreform. Det er dog som et plaster på et åbent benbrud. Det skriver jeg om i @Altingetdk #dkpol www.altinget.dk/forskning/ar...

Looking for a PhD position in statistical methods development for causality? Then we might be looking for you! jobportal.ku.dk/alle-opslag/...

The Pioneer Centre for SMARTbiomed will leverage large-scale, multimodal biomedical data combined with focused innovation in statistical and computational methods including machine learning to advance our understanding, treatment, and prevention of human disease. Learn more about us: smartbiomed.dk

The scientist who is responsible for driving GLP-1 drugs for the treatment of obesity and testing them for prevention of Alzheimer's disease—Lotte Bjerre Knudsen— tells her story in a remarkable conversation. Full transcript, or video, all free, no ads. erictopol.substack.com/p/lotte-bjer...

Interesting work! By mapping many medical ontologies to the same embedding space we can go beyond the need of time-consuming data mapping and harmonization. www.medrxiv.org/content/10.1...

Million Veteran Program & FinnGen teams are pleased to release v1 meta-analysis of MVP, FinnGen and UKBB GWAS data. This first version includes ~300 binary disease definitions across >1.5 M individuals. Browse scans at: mvp-ukbb.finngen.fi

📢 New publication from our group: a comprehensive study on mental health disorder trends in Denmark according to age, calendar period, and birth cohort We are excited to announce the publication of our latest research in JAMA Psychiatry: jamanetwork.com/journals/jam... More details below.

Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!

There are now 50 papers (that I am now aware of) with methods for transferring polygenic scores across populations. You can find them here: drive.google.com/drive/folder...

Check out our (Emil Pedersen, Theresa Wimberley, and me) news and views out today in Nature Genetics, highlighting the importance of selection bias and information bias in genetic studies. #statgen #genepi #selectionbias eur01.safelinks.protection.outlook.com?url=https%3A...

🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.

We are thrilled to announce that Professor Niels Mejlgaard will assume the role of CEO of the DNRF on January 13, 2025. Learn more: dg.dk/en/new-ceo-o...

Very interesting work by Tade Souaiaia et al on the non-polygenic architecture of the extremes of complex traits. For many traits, polygenic scores show "regression to the mean" around the tails, as extreme traits are mostly due to rare alleles. www.biorxiv.org/content/10.1...

The Amazing Florian Privé has joined Bluesky. He’s the author of several great R packages in #statgen, including bigsnpr and bigstatsr. 😀

The preliminary #eshg25 program is online. Stellar line-up of invited speakers - full breadth of our amazing field. Grateful to a wonderful SPC @eshg that made this possible. See you all in Milan next year! 2025.eshg.org/programme-at...

I wrote about Eric Turkheimer's recent book on "the nature-nurture debate", which should be of interest to people thinking not just about the genetics of behavior but complex traits more broadly. A 🧵:

The European Health Data Space (EHDS) act represents a incredible opportunity for health data science In a Nature Medicine commentary we discuss the present and future of EHDS This is the result of a workshop with some incredible researchers across EU countries and disciplines rdcu.be/dTKUj

Amazing methods-oriented PIONEER center of Biomedicine launching in DK and UK, led by Naomi Wray, @ceclindgren.bsky.social @bvilhjal.bsky.social Preben Bo Mortensen, Erin Gabriel, Chris Holmes, Peter Visscher

From @bvilhjal.bsky.social and co: Inferring disease architecture and predictive ability with LDpred2-auto www.cell.com/ajhg/fulltex...

Family-based GWAS have become the gold standard for assessing causal genetic effects. They’re often said to offer an unbiased estimate of the average causal effect (ATE) of an allele or PGS. Here, we (Carl Veller & @mollyprz.bsky.social ) evaluate such statements. www.biorxiv.org/content/10.1... 1/n

Is anyone here 🧬🖥️ using the UKBiobank 200k genome dataset? We are having some weird issues and are trying to troubleshoot if data vs code. Anyone else seeing anything odd? Either way, please share (not sure what the equivalent of RT here is?)

On our way to #wcpg2023! This is a big year for Cai lab, all of us have talks! 🤩 Lianyun Huang is in the UKB session, Jolien Rietkerk is in the stats methods session, and I’m in a symposium on GWAS phenotyping. I’ll remind everyone on the morning of. 😉 See you all in Montreal!

This is a Bluesky feed that tracks #WCPG2023 posts for the world congres of psychiatric genetics 2023, SUBSCRIBE!: bsky.app/profile/did:...

Excited to share our latest manuscript on gene-environment interactions in the UKBiobank: www.medrxiv.org/content/10.1...

@amirsariaslan.bsky.social tusind tak for invite 😀👍