Ellie Boardman
@ellieboardman.bsky.social
📤 243
📥 247
📝 15
Postdoc working in Ben Berks’s group at the University of Oxford
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Ellie Boardman
James Connolly
2 days ago
Huge congratulations to
@rhyswg.bsky.social
and colleagues for this behemoth of a paper shedding light onto the mechanism of pyocins and their impact on cell function.
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L-type pyocins inhibit the BAM complex to kill without cell entry - Nature Communications
L-type pyocins are a class of bacteriocin-like proteins with antibacterial activity. Here, the authors show that these proteins kill the pathogen Pseudomonas aeruginosa by inhibiting the BAM complex a...
https://www.nature.com/articles/s41467-026-74995-w
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Ellie Boardman
Basler Lab
7 days ago
A Garmin watch face with a living microbial battlefield powered by your daily stats that is never the same! 🦠⌚️ The BacFighT6 Watch Face runs a live,
#T6SS
mediated bacterial simulation on your wrist.
apps.garmin.com/apps/eaf881d...
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Ellie Boardman
Tracy Palmer
10 days ago
This has been such a fun collaboration and a great example of team science
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Fab to see this out finally! Lots of hard work from all involved 🥳
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9 days ago
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Ellie Boardman
Tracy Palmer
11 days ago
Check out our latest T7SS toxin story. These reverse toxins aren’t as rare as we thought!
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Nature Microbiology
12 days ago
Out Now! Structure and substrate recognition by the bacterial twin-arginine translocation (Tat) core complex
#MicroSky
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Structure and substrate recognition by the bacterial twin-arginine translocation (Tat) core complex
Nature Microbiology, Published online: 22 June 2026; doi:10.1038/s41564-026-02399-zCryo-EM structural, biochemical and functional analyses of the bacterial twin-arginine translocation system for protein transport across membranes reveal mechanisms of substrate binding.
https://go.nature.com/4w8ovO7
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Ellie Boardman
Nature Microbiology
16 days ago
Out Now! A phage takes the wheel
#MicroSky
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A phage takes the wheel
Nature Microbiology, Published online: 19 June 2026; doi:10.1038/s41564-026-02405-4Prophage FRφ rewires the flagellar apparatus of its Enterobacter sp. host through RNA-guided repression of native flagellin, favouring its own phage-encoded isoform. This enhances host motility and reduces immune recognition, boosting bacterial fitness in mice.
https://go.nature.com/4oEw1gR
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Ellie Boardman
Susan Lea
19 days ago
A lot of work, over many years, and we finally see the missing piece at the heart of type 3 export!
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Ellie Boardman
bioRxiv Microbiology
19 days ago
Structure of the proton-powered secretion motor at the heart of the bacterial flagellum
https://www.biorxiv.org/content/10.64898/2026.06.13.732081v1
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Cara Giovanetti
21 days ago
This pit of fire has been burning for 55 years. And there’s something ALIVE at the bottom of it! 1/7 ⚛️🧪
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Ellie Boardman
James Connolly
about 1 month ago
Latest research from the lab out now. We examined the role and expression of fimbriae during UPEC bloodstream infection. A real team effort and brilliant collaboration with Mark Schembri’s lab in Brisbane. Thanks to the MRC and BBSRC for supporting our research
@ukri.org
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Yad fimbriae are triggered by host cues and enhance extraintestinal pathogenic Escherichia coli tissue colonisation during bloodstream infection
Author summary Extraintestinal pathogenic Escherichia coli (ExPEC) colonise the human gut without causing disease but can disseminate to the urinary tract and bloodstream. Understanding the mechanisms...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1014299
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Ellie Boardman
EMBO
about 1 month ago
Register now for the EMBO Workshop "Advances and new frontiers in #ProteinTranslocation across membranes" in Sant Feliu de Guixols, Spain, 21–25 Sep 2026. Abstract submission/Registration by 19/30 Jun
https://meetings.embo.org/event/26-protein-translocation
#ProteinTranslocation
#EMBOProteinTranslocation
#EMBOevents
🧪
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Ellie Boardman
The Lister Institute of Preventive Medicine
2 months ago
Rejection is part of science. So is resilience. 🔬 Tim Blower and
@stewartlab.bsky.social
share how setbacks helped shape their careers. We don't talk about this enough. 🔁Please repost and share your own stories of defeat or bouceback. Break the stigma!
lister-institute.org.uk/news/resilie...
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Ellie Boardman
Charles Winterhalter
2 months ago
What are the genetic and molecular determinants underpinning the repair of bidirectional replication fork collapse in bacteria? PhD position open in my lab in collaboration with the brilliant
@heathmurraylab.bsky.social
. Please share and contact me if interested:
www.findaphd.com/phds/project...
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Identifying bacterial DNA repair requirements enabling stable genetic inheritance during bidirectional replication fork collapse at Newcastle University on FindAPhD.com
PhD Project - Identifying bacterial DNA repair requirements enabling stable genetic inheritance during bidirectional replication fork collapse at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/identifying-bacterial-dna-repair-requirements-enabling-stable-genetic-inheritance-during-bidirectional-replication-fork-collapse/?p196441
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Ellie Boardman
Lis Lowe
2 months ago
We have a PhD studentship open! (UK only sadly) but if you are or know a student keen to work on some *really* weird mycobacterial enzymes then get in touch!
#glycotime
Advert below
www.findaphd.com/phds/project...
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Uncovering a new class of toxins in pathogenic mycobacteria at Newcastle University on FindAPhD.com
PhD Project - Uncovering a new class of toxins in pathogenic mycobacteria at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/uncovering-a-new-class-of-toxins-in-pathogenic-mycobacteria/?p196373
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Ellie Boardman
Lis Lowe
3 months ago
We’ve been sciencing! M abscessus makes a arabinanase toxin to chop up the cell wall of competitor mycobacteria!
#glycotime
🦠 thanks to
@wellcometrust.bsky.social
for the funding that makes this collaborative work possible! Also Sam’s structures are 😍 and Jean-Lou did some lovely biochem
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Ellie Boardman
Félix Ramos-León
4 months ago
Our work on understanding how Staphylococcus aureus mode of cell division contributes to pathogenesis is now available in bioRxiv
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Come work with us in Oxford!
www.jobs.ac.uk/job/DQL601/p...
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4 months ago
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Ellie Boardman
MRC Laboratory of Molecular Biology
4 months ago
Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme? Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues. Apply by 16 MAR
www.nature.com/naturecareer...
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Ellie Boardman
Luca Troman
5 months ago
🌀 How do spirochete bacteria swim through thick fluids like champions? We solved T. denticola flagella structure - asymmetric proteins expand one side, compress the other for perfect corkscrew motion!
@debnathghosal.bsky.social
🔗
doi.org/10.64898/202...
#StructuralBiology
#CryoEM
#Microbiology
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7 years to the day that I started in
@proftracypalmer.bsky.social
’s lab I am leaving for pastures new in Ben Berks’s lab at Oxford Biochemistry! It’s a very sad goodbye but onto exciting new things!
6 months ago
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Ellie Boardman
Giusy Mariano
8 months ago
Excited to share our new study! Great fun working again with my good friend
@stephenrgarrett.bsky.social
— always a highlight! Huge thanks to fantastic co-authors
@samkaytucker.bsky.social
,
@drandyjroe.bsky.social
and our star technician Vojtech Pavelka.
academic.oup.com/nargab/artic...
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Ellie Boardman
Syma Khalid
8 months ago
We are back, soon! The secrets of bacterial cell envelopes' our free online seminar series is due to resume in January 2026 after a long break. Hosted by Georgina Benn and Syma Khalid- supported by the Microbiology Society. More details soon.
@microbiologysociety.org
Please spread the word
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Ellie Boardman
Basler Lab
8 months ago
Happy to share our latest T6SS review:
nature.com/articles/s41...
Thank you, Jan, Danny (
@dannyjamesward.bsky.social
), Joana (
@joanampereira.bsky.social
), as well as reviewers and editors
@natrevmicro.nature.com
!
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The type VI secretion system and associated effector proteins - Nature Reviews Microbiology
In this Review, Basler and colleagues examine the type VI secretion system (T6SS), focusing on the diversity of antibacterial T6SS effectors and the evolutionary forces that shape them. They explain h...
https://nature.com/articles/s41579-025-01256-w
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Ellie Boardman
James Connolly
8 months ago
Theres still time to apply for our PhD project on UPEC/immune cell interactions. Deadline December 4th
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Ellie Boardman
MadScientist
8 months ago
"Postdoc in the job market"
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Ellie Boardman
Giusy Mariano
8 months ago
🚨 PhD Opportunity 🚨 Interested in microbiology, phages & water security? Join me and Prof Cindy Smith to test phages as a sustainable alternative to chlorine in drinking-water biofilters. Metagenomics, phage discovery & ecology — all in one exciting project! Apply:
www.gla.ac.uk/colleges/mvl...
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Ellie Boardman
Simona Huwiler
8 months ago
Our article on a 🛠️ molecular toolbox 🛠️ in predatory bacterium 🦁🦠 Bdellovibrio bacteriovorus is published in PLOS Genetics (=>
tiny.cc/6wuu001
). 🎉 This supports the research on this bacterial predator-prey system & future bioengineering efforts.
#MicroSky
#SyntheticBiology
#PredatoryBacteria
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Ellie Boardman
apreston243.bsky.social
8 months ago
New paper alert! DNA replication and repair conflicts lead to cell death in gram positive bacteria, possible new targets for novel antimicrobials.
@microbiologysociety.org
@winterhalterlab.bsky.social
www.microbiologyresearch.org/content/jour...
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Conflicts between the DNA replication and repair machineries promote cell death in Gram-positive bacteria
Cellular proliferation relies on the successful coordination and completion of genome replication and segregation. To help achieve this, many bacteria utilize regulatory pathways that ensure DNA repli...
https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.001633
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Ellie Boardman
CBCB Newcastle
8 months ago
Looking for a PhD opportunity in Microbiology? Consider joining one of the UK's leading microbiology research clusters at Newcastle University. See the thread for MRC DTP studentships currently advertised.
@medicalsciencesncl.bsky.social
@sagencl.bsky.social
@cbcb-newcastle.bsky.social
#microsky
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Ellie Boardman
Newcastle University Structural Biology Facility
8 months ago
We are very much looking forward to the Grand Opening of the Northern Eye Imaging facility tomorrow! Follow us here for all the news coming from NUSBF!
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We’ve kept registrations open till the end of this week so get your last minute applications in for posters and talks!
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9 months ago
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Ellie Boardman
Kate Beckham
9 months ago
Still time to sign up and submit and abstract for this year’s CCP4 Northern Structural Biology Meeting. This is a really nice meeting and great opportunity for ECRs to present their work ✨
nusbf.ncl.ac.uk/ccp4-norther...
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https://nusbf.ncl.ac.uk/ccp4-northern-conference-2025/
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The CCP4 Northern Structural Biology Meeting is back again in Newcastle 6-7th November 2025. If you are a structural biologist/biochemist in the North of the UK please register and submit abstracts by this Friday 17th.
nusbf.ncl.ac.uk/ccp4-norther...
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https://nusbf.ncl.ac.uk/ccp4-northern-conference-2025/
9 months ago
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Ellie Boardman
Pilhofer Lab 🦠❄️🔬
9 months ago
🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System
@xujwet.bsky.social
&@chipericson.bsky.social trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal
#cryoEM❄️🔬
www.biorxiv.org/content/10.1...
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Ellie Boardman
Microbes in Health and Disease
9 months ago
I’m Chloe, I am part of the Connolly lab and I study how the role of two-component systems differs between types of E.coli”
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Ellie Boardman
Microbes in Health and Disease
9 months ago
Hi, I’m Natalia Łoś from Dr Dave Bolam’s lab. I’m currently going into the third year of my PhD working on dietary fibre degradation by the members of the human gut microbiota 😊 Follow Natalia here :
@natalia-los.bsky.social
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Ellie Boardman
Microbes in Health and Disease
9 months ago
In MHD we are lucky enough to have an amazing group PhD Students and Research Associates. We’ve recently got some new representatives and would like give them the opportunity to introduce themselves here. First up our two representatives for the PhD student community:
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Ellie Boardman
Tracy Palmer
9 months ago
Check it out! A proper team effort from past and present group members and a great collaboration with
@sergemostowylab.bsky.social
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Ellie Boardman
John Innes Centre
9 months ago
VACANCY - Independent research fellowships leading to tenured positions We’re inviting applications from outstanding researchers who either hold, or wish to apply for, Independent Research Fellowships. APPLICATION DEADLINE: 10 November 2025 Click here to apply:
jic.link/Fellows
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Ellie Boardman
Augustinas Silale
9 months ago
We think this much larger BAM enables biogenesis of outer membrane β-barrel and surface-exposed lipoprotein complexes, which are a hallmark of the Bacteroidota.
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Ellie Boardman
Augustinas Silale
9 months ago
Berks and
@smlea.bsky.social
labs also found yet a different BAM architecture in Flavobacterium johnsoniae, another member of Bacteroidota.
doi.org/10.1038/s415...
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A new paradigm for outer membrane protein biogenesis in the Bacteroidota - Nature
Structural and biochemical studies of the β-barrel-assembly machinery from Flavobacterium johnsoniae reveal a subunit composition and assembly that are distinct from those of the canonical Escherichia coli complex.
https://doi.org/10.1038/s41586-025-09532-8
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Ellie Boardman
Augustinas Silale
9 months ago
Our paper on the Bacteroidota BAM complex is out in
@natmicrobiol.nature.com
! With
@madejmar.bsky.social
We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.
doi.org/10.1038/s415...
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Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota - Nature Microbiology
Structural and functional characterization of the β-barrel assembly machinery complex in Bacteroidota reveals a distinct, seven-component complex with a large extracellular domain that may enable β-barrel–surface lipoprotein complex assembly.
https://doi.org/10.1038/s41564-025-02132-2
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Great opportunity to do a PhD with Giusy and co in Glasgow!
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9 months ago
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Nice to see our summer student Niamh who did a great job in the lab this year supported by a Vacation Studentship!
@proftracypalmer.bsky.social
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9 months ago
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Ellie Boardman
Tracy Palmer
9 months ago
Exciting postdoc opportunity with a fab PI in beautiful Basel
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Ellie Boardman
Wilbert Bitter
9 months ago
PPE51 is one of the best candidates to form a MOM transport channel. However, our data indicate that it is not that simple. PPE51 mutations in Mmarinum (4 close homologs) indeed reduce the growth on glycerol & glucose, but also highly increase permeability.. and no, we do not fully understand this
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PPE51 modulates membrane integrity in Mycobacterium marinum | mBio
The impermeable outer membrane of pathogenic mycobacteria presents a major obstacle to nutrient acquisition and antibiotic penetration. PPE51, a substrate of the ESX-5 secretion system, has previously...
https://journals.asm.org/doi/10.1128/mbio.01044-25
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Ellie Boardman
Microbes in Health and Disease
10 months ago
Last introduction for the today.. Dr Kesha Josts
@kjosts.bsky.social
The Josts lab are working on the mechanisms of iron transport in bacterial pathogens, with a focus on Pseudomonas aeruginosa.
www.ncl.ac.uk/cbcb/staff/p...
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Ellie Boardman
Microbes in Health and Disease
10 months ago
Next introducing Dr Alessandra Dantas. The Dantas group is interested in stress responses, antifungal resistance and in understanding the molecular mechanisms driving fungal adaptation to environmental stressors.
@alesdantas.bsky.social
www.ncl.ac.uk/dental/about...
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