N End Rules
@n-end-rules.bsky.social
📤 344
📥 173
📝 15
Destabilising..
pinned post!
My first
@bsky.app
post could only be
#crossing
two accessions of
#arabidopsis
from very different 🏔️
#genetics
#plantscience
a kind of meditation.
over 1 year ago
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New Phytologist
1 day ago
Generation of Brassica napus with enhanced Sclerotinia sclerotiorum resistance through CRISPR/Cas9‐mediated inhibition of the PROTEOLYSIS6 N‐degron pathway Lin et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
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The N-degron pathways move from basic to applied science. This pathway will prove to be of key importance for agricultural improvement. Very happy to have been a part of this work led by Chen Lin and colleagues.
#plantscience
#nendrule
#hypoxia
nph.onlinelibrary.wiley.com/doi/10.1111/...
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Generation of Brassica napus with enhanced Sclerotinia sclerotiorum resistance through CRISPR/Cas9‐mediated inhibition of the PROTEOLYSIS6 N‐degron pathway
Click on the article title to read more.
https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.71146
1 day ago
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8 days ago
🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in
@science.org
, we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗
www.science.org/doi/10.1126/...
#EvoDevo
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Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration
Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...
https://www.science.org/doi/10.1126/science.adw8526
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COS Heidelberg
11 days ago
New publication from Markus Wirtz and colleagues on N-terminal protein acetylation:
www.nature.com/articles/s41...
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The ribosome-associated N-terminal acetyltransferase B coordinates global proteostasis and autophagy in plants by creating Ac/N-degrons - Nature Communications
Protein N-terminal acetylation profoundly influences protein fate. Here, the authors establish NatB as a central regulator of the interplay between ubiquitin–proteasome system and autophagy, and highl...
https://www.nature.com/articles/s41467-026-71208-2
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CRAG
21 days ago
🌱 CRAG launches an international call for early‑career researchers! We invite young scientists interested in starting their independent research group at CRAG 📅 Deadline - April 26 Apply now 👉
https://f.mtr.cool/jdwzombrbd
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ProteostasisUK
about 1 month ago
Proteostasis UK Logo Competition Design our new logo and win registration, UK‑based travel, and accommodation to attend the UK Proteostasis Meeting 2026, 20–21 July at The Francis Crick Institute, London. See here for more information:
proteostasisuk.co.uk/calls/proteo...
Deadline: 1st May 2026
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about 1 month ago
I am definitely where I belong! So proud of me right now 🥰 and grateful of my support system in this team 🥂!
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Mikel Lavilla-Puerta
about 1 month ago
Finally officially out!!
www.pnas.org/doi/10.1073/...
We moved the main oxygen sensing machinery from plants to yeast and we learned a few things!
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A synthetic ERFVII-dependent circuit in yeast sheds light on the regulation of early hypoxic responses of plants | PNAS
Plants face hypoxic conditions either chronically, as particular tissues are characterized by fluctuating or stable low oxygen levels, or acutely, ...
https://www.pnas.org/doi/10.1073/pnas.2524358123
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Daan Weits
about 1 month ago
What features are required to shape hypoxic niches enclosing meristems? We
@viktoriiavoloboeva.bsky.social
in collab
@pieterverboven.bsky.social
found that a combination of cuticle barrier, densely packed tissue and metabolic activity all uniquely contribute to maintain shoot apical meristem hypoxia
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Mark Avery
about 1 month ago
Marsh Clubmoss rediscovered in Dunbartonshire by
@bsbiscotland.bsky.social
of
@bsbibotany.bsky.social
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The EMBO Journal
about 1 month ago
Asgard
#archaea
: have we found our microbial ancestors? New review (also for newcomers to the field!) by Christa Schleper and Thiago Rodrigues-Oliveira
link.springer.com/article/10.1...
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Plant Energy Biology Lab
about 1 month ago
Freshly online 🗞️ In Vivo Monitoring of Energy Metabolism with Genetically Encoded Fluorescent Biosensors 🌱🔋🌈🔬
@jan-oleniemeier.bsky.social
@morganlab-saarland.bsky.social
@uni-muenster.de
doi.org/10.1146/annu...
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In Vivo Monitoring of Energy Metabolism with Genetically Encoded Fluorescent Biosensors
All organisms fuel and build themselves through their energy metabolism. While classic biochemistry conceptualizes the fluxes of energy and matter, our understanding of how energy metabolism works in ...
https://doi.org/10.1146/annurev-arplant-071425-085632
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Back to crossing, this time with the horrible mutant nia1 nia2
#arabidopsis
#genetics
#plantscience
about 1 month ago
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Karolina Heyduk
about 2 months ago
I'd like to remind everyone that CAM has evolved as many if not more times than C4. There are entire biomes where CAM is dominant. If you like tequila, or pineapple, or your pretty orchid you got at the grocery store, you can thank CAM. Thank you for coming to my TEDtalk. Or CAMtalk as it were.
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Abiotic Stress in Plants
about 2 months ago
Rewiring an E3
#ligase
enhances
#cold
resilience and
#phosphate
use in
#maize
www.nature.com/articles/s41...
#PlantScience
#SciComm
@nature.com
@natcellbio.nature.com
@maizesausage.bsky.social
@plantnerd.bsky.social
@jchrispires.bsky.social
@mrillig.bsky.social
@nmouquet.bsky.social
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Rewiring an E3 ligase enhances cold resilience and phosphate use in maize - Nature
The E3 ubiquitin ligase NLA postively regulates cold tolerance and negatively regulates phosphate uptake in maize, and a genetically engineered variant of this enzyme leads to improved cold ...
https://www.nature.com/articles/s41586-026-10142-1
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Abiotic Stress in Plants
about 2 months ago
Switching on and off the
#hypoxic
response in
#plants
academic.oup.com/jxb/advance-...
#PlantScience
#SciComm
@jxbotany.bsky.social
@olmiemma.bsky.social
@theplantlab.bsky.social
@isplore.bsky.social
@n-end-rules.bsky.social
@hartman-plantlab.com
@plantstress.bsky.social
@plantredox.bsky.social
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Switching on and off the hypoxic response in plants
Abstract. Hypoxia significantly impacts plant metabolism and growth by disrupting mitochondrial respiration, and oxygen sensing plays a vital role in regul
https://academic.oup.com/jxb/advance-article/doi/10.1093/jxb/erag101/8495722?login=false
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Pierdomenico Perata
about 2 months ago
Switching on and off the hypoxic response in plants url:
academic.oup.com/jxb/article/...
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Switching on and off the hypoxic response in plants
Abstract. Hypoxia significantly impacts plant metabolism and growth by disrupting mitochondrial respiration, and oxygen sensing plays a vital role in regul
https://academic.oup.com/jxb/article/doi/10.1093/jxb/erag101/8495722
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John Christie
about 2 months ago
Feeling blue? Find out more about the dark side of phototropin signalling 😀
academic.oup.com/plcell/advan...
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Reversible phosphorylation of NPH3/RPT2-like proteins regulates phototropin receptor signaling
Phototropin receptor signaling requires PP2C19 and PP2C35 to dephosphorylate NPH3 and related substrates, ensuring efficient phototropism and chloroplast m
https://academic.oup.com/plcell/advance-article/doi/10.1093/plcell/koag043/8493238
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Journal of Experimental Botany
about 2 months ago
🔗
doi.org/10.1093/jxb/...
#PlantScience
🧪
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Yoselin Benitez-Alfonso
about 2 months ago
One as Head of Plant Science at Leeds The new Plant Sciences page is now live and linked to from the FBS Research and Innovation homepage - interested in joining or collaborating? Learn about the research and opportunities by visiting this website!
biologicalsciences.leeds.ac.uk/plant-sciences
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Centre for Plant Sciences
https://biologicalsciences.leeds.ac.uk/plant-sciences
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Emma Olmi
about 2 months ago
Happy to see our review online in
@jxbotany.bsky.social
🌱 In this work, we provide an overview of the molecular mechanisms plants use to survive under low oxygen stress and during recovery after reoxygenation 🌊
doi.org/10.1093/jxb/...
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Switching on and off the hypoxic response in plants
Abstract. Hypoxia significantly impacts plant metabolism and growth by disrupting mitochondrial respiration, and oxygen sensing plays a vital role in regul
https://doi.org/10.1093/jxb/erag101
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Dan Gibbs 🌱🧬
about 2 months ago
My review “Co-translational control of protein stability and quality in plants” is now online at
@jxbotany.bsky.social
, in which I describe how co-translational processing and ribosome-associated quality control together establish protein stability and fate early in synthesis.
tinyurl.com/5dhhz9h6
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Co-translational control of protein stability and quality in plants
Abstract. Proteostasis relies on the coordinated control of protein synthesis, folding, modification and degradation, and an increasingly clear picture is
https://tinyurl.com/5dhhz9h6
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about 2 months ago
I completely agree. However, I’ve found that several Chinese researchers publishing impactful work recently haven't responded to my invitations. If you have other recommendations—perhaps colleagues who are particularly active—please let me know!
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International Society for Protein Termini (ISPT)
2 months ago
Protein event of the year - sign up today! See you at beautiful Palazzo dei Normanni in Palermo for the FEBS 2026 Protein Termini Workshop.
#ProteinTermini
#Proteostasis
#ProteinModifications
#StructuralBiology
#PalazzoDeiNormanni
#Palermo2026
proteintermini.org/meeting/
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International Society for Protein Termini (ISPT)
about 2 months ago
8 days left to register | 28 invited speakers | Keynotes from F. Ulrich Hartl, Roland Beckmann and Michael Rapé |
#chaperones
#degradation
#ubiquitin
#cryoEM
#acetylation
#lipidation
#ribosomes
#proteins
proteintermini.org/meeting/
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Protein Termini 2026 – International Society for Protein Termini (ISPT)
https://proteintermini.org/meeting/
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2 months ago
Join us in Palermo! FEBS Workshop Protein Termini 2026: the power of protein termini across bacteria, plants, and animals—from ribosome biology to proteostasis and applications. Deadline: 3 March 2026
proteintermini.org/meeting
#ProteinTermini
#Proteostasis
#FEBS
#EMBO
@iubmb.bsky.social
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Edoardo Gianni
2 months ago
How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in
@science.org
on a new small polymerase. 1/n
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A small polymerase ribozyme that can synthesize itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
https://www.science.org/doi/10.1126/science.adt2760
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Sad to say that after 14 years of service the vseed server
vseed.nottingham.ac.uk
will soon be retired. Do not despair our community resource for seed germination network analysis is still available at
netvis.ico2s.org/dev/seednet/#/
thanks to Professor Natalio Krasnogor at Newcastle University
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http://vseed.nottingham.ac.uk
2 months ago
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Surprisingly: "Conditional stability of HY5 through the ATE N-degron pathway regulates environmental responses in Arabidopsis thaliana". The shining bounds of N-degron pathway influence expands!
@charlene-kunaka.bsky.social
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.02.10.705009v1
2 months ago
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bioRxiv Plant Bio
2 months ago
Conditional stability of HY5 through the ATE N-degron pathway regulates environmental responses in Arabidopsis thaliana
https://www.biorxiv.org/content/10.64898/2026.02.10.705009v1
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3 months ago
Are you, or do you know someone that is excited to do a PhD in plant biology. We are happy to offer a position to explore physiology, gene regulatory networks and wild species. Come join our team in a stimulating scientific environment at the University of Groningen!
werkenbij.rug.nl/vacature/phd...
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PhD position Growth-resilience trade-offs in plants - Rijksuniversiteit Groningen
https://werkenbij.rug.nl/vacature/phd-position-growth-resilience-trade-offs-in-plants-1634/?lang=en
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Mark A. Hanson
3 months ago
We've got ISSUES. Literally. We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A 🧵 1/n
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New Phytologist
3 months ago
Discrete and cell-specific hypoxic responses in Arabidopsis roots resolved by single-nuclei transcriptomics Hill et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
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The BanLab
4 months ago
Last X-Mas, the ribosome gave you methionine, but the very next day, MetAP took it away. This year, to save histones from tears, NatD gives you an acetyl group. ⭐️ Explore our latest paper with the Deuerling lab
@uni-konstanz.de
and Shu-ou Chan lab
@caltech.edu
!
www.science.org/doi/10.1126/...
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Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD
NAC enables cotranslational N-terminal processing of histones H2A and H4 by recruiting MetAP1 and NatD at the ribosomal tunnel.
https://tinyurl.com/ycypkzpt
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Rory Osborne
4 months ago
So happy to see this work finally online! In this Research Review, I discuss the emerging roles of H3K27me3 writers (the enzymes that lay it down) and erasers (the enzymes that remove it) in controlling plant adaptation 🌿🌡️❄️🦠
nph.onlinelibrary.wiley.com/doi/10.1111/...
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Finding balance: the dynamic interplay between H3K27me3 writers and erasers in regulating environmental plasticity and memory
Subject to an ever-changing world, plants must respond to harmful conditions and environmental fluctuations. Their evolutionary success can be attributed to their plasticity in both perceiving and in...
https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.70815
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Richard Sever
4 months ago
UKRI exploring use of AI in grant review - this will prompt debate but interested to know if people think it’d encourage novelty or the opposite?
www.chemistryworld.com/news/ukri-op...
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UKRI opens up grant proposal data to explore using AI to smooth peer review
Surging applications has led the UK's main funder to look at ways to reduce the burden on reviewers
https://www.chemistryworld.com/news/ukri-opens-up-grant-proposal-data-to-explore-using-ai-to-smooth-peer-review/4022597.article
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What a terrible terrible idea
add a skeleton here at some point
4 months ago
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Sjon Hartman
4 months ago
Lovely new review on H3K27me3 dynamics and potential functions in
#plantscience
by
@drosborneplantsci.bsky.social
nph.onlinelibrary.wiley.com/doi/10.1111/...
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Finding balance: the dynamic interplay between H3K27me3 writers and erasers in regulating environmental plasticity and memory
Subject to an ever-changing world, plants must respond to harmful conditions and environmental fluctuations. Their evolutionary success can be attributed to their plasticity in both perceiving and in...
https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.70815
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Dr Steve Westlake
4 months ago
This is scary. "Three of the five worst harvests on record have now occurred since 2020, leaving some farmers asking whether the growing impacts of the climate crisis are making it too financially risky to sow their crops."
www.theguardian.com/environment/...
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UK farmers lose £800m after heat and drought cause one of worst harvests on record
Many now concerned about ability to make living in fast-changing climate after one of worst grain harvests recorded
https://www.theguardian.com/environment/2025/dec/04/record-heat-drought-2025-cost-uk-arable-farmers-estimated-800m-climate-crisis-grain-harvest?CMP=Share_AndroidApp_Other
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Peter Mabbitt
5 months ago
We’ve made some new tools to manipulate N-recognins. Check them out in our preprint.
www.biorxiv.org/content/10.1...
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Just registered for FEBS advanced workshop Protein termini 2026 in Palermo
#proteintermini2026
(?) Looking forward to a great meeting.
@ispt-proteinterm.bsky.social
www.conferencecentral.org/webpage/view...
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FEBS Workshop 'Protein termini 2026: From mechanisms to biological impact'
https://www.conferencecentral.org/webpage/view/45
5 months ago
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Plantae.org
5 months ago
📅New
#PlantSciEvents
Event Added: FEBS Workshop ‘Protein termini 2026: From mechanisms to biological Impact’ 👉
buff.ly/hblFxeR
#PlantScience
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FEBS Workshop ‘Protein termini 2026: From mechanisms to biological Impact’
(2026) Wed 3 Jun - Sat 6 [EDT]: The FEBS Workshop 'Protein termini 2026: From mechanisms to biological impact' is the 5th biennial conference of the International Society for Protein Termini (ISPT)…
https://buff.ly/hblFxeR
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A new plant oxygen sensing mechanism, based on methylation of histone H3 What a fantastically interesting story this is, congratulations to the authors!
add a skeleton here at some point
5 months ago
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KWS Group
5 months ago
Europe cannot afford to fall behind on innovation! We join 25 EU agri-food organizations urging policymakers to conclude
#NGTs
trilogue talks now. Science-based rules = resilient crops & global competitiveness. Act today! 🌱
euroseeds.eu/app/uploads/...
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Isa MG
5 months ago
🏔️🌧️ 🧬 We wrote this Expert View on oxygen sensing, you can read it here! 👇🏼
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Recent advances in the mechanism, transduction and function of oxygen sensing in plants
#nendrule
#hypoxia
#plantscience
academic.oup.com/jxb/advance-...
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Recent advances in the mechanism, transduction and function of oxygen sensing in plants
Abstract. Response to reduced ambient oxygen is a key component of plant adaptation in natural and farmed environments and is regulated by oxygen dependent
https://academic.oup.com/jxb/advance-article/doi/10.1093/jxb/eraf515/8340058
5 months ago
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Louisa Whitton
5 months ago
There once was a man who said "scone" So that it rhymed with "gone", But his wife said "scone" To rhyme with "tone"; That marriage is over, it's done.
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Andrea Paterlini (he/him)
5 months ago
Few Plant science programmes are left in the UK and they are critical to train the next generation. This move by
@uniofnottingham.bsky.social
goes against recommendations made in the recent PS Education manifesto. Big mistake! Sign the petition!
nph.onlinelibrary.wiley.com/doi/10.1002/...
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Dr Susannah Lydon
5 months ago
My students have set up a petition to persuade the University of Nottingham not to close our Plant Biology BSc course
c.org/VPhzVVrHPS
Please consider signing
add a skeleton here at some point
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