In #G3journal, @elena-kuzmin.bsky.social et al. present PARPAL database, a valuable resource for #yeast researchers to understand the retention and evolution of paralogs. A phenomics screen further shows how proteins respond to paralog deletion by localization & abundance changes. buff.ly/oM97WyH

Our manuscript on the PARPAL database is out in G3! We share our phenomics screen on how proteins respond to their paralog deletion by localization & abundance changes and integrate other datasets with collab @guilbourque.bsky.social @leopoldparts.bsky.social doi.org/10.1093/g3jo...

At long last, Rosalind's paper on comparing methods for paralog synthetic lethality is online: genomebiology.biomedcentral.com/articles/10....

Our manuscript on how single-cell imaging of protein dynamics of paralogs reveals sources of gene retention is out in iScience with a great team of collaborators @leopoldparts.bsky.social @guilbourque.bsky.social www.cell.com/iscience/ful...

Please check out our new approach to modeling somatic mutation signatures. DAMUTA has independent Damage and Misrepair signatures whose activities are more interpretable and more predictive of DNA repair defects, than COSMIC SBS signatures 🧬🖥️🧪 www.biorxiv.org/content/10.1...

Join us for the 2025 SynBio7.0 conference in Toronto, June 1-3! SynBio is Canada's largest academic synthetic biology conference. More details on our website! synbio7.vercel.app

Last call for a postdoc position in single cell analysis/perturb-seq with @nikashakiba.bsky.social at UBC in beautiful Vancouver Canada! ubc.wd10.myworkdayjobs.com/en-US/ubcfac...

The Early Bird Registration & Submission Deadline is approaching: March 28, 2025! 🔗 Register now premc.org/yeast2025/re... Don’t wait until the last minute, spots are limited and allocated on a first-come, first-served basis 🌟 the list of Outstanding Invited Speakers premc.org/yeast2025/in...

Just add sorbitol! onlinelibrary.wiley.com/doi/full/10....

Great study to have been involved in!

Very excited to share our preprint on the PARPAL web data portal capturing how proteins change their subcellular localization and abundance due to their paralog deletion w/ collab @leopoldparts.bsky.social @guilbourque.bsky.social www.biorxiv.org/content/10.1...

Some science news to brighten up your timelines ☀️ Our latest work on the modifiers that cause changes in gene essentiality between genetic backgrounds, now on bioRxiv: www.biorxiv.org/content/10.1... So what did we find?

We are hiring a Tier II Canada Research Chair (CRC) in Synthetic Biology and Biomanufacturing at Concordia University. Please, repost. www.concordia.ca/artsci/about...