Checkout the latest preprint from the lab - single-cell CIN signatures unlocked! Ongoing HRD improves PARPi sensitivity detection and ongoing NHEJ associates with subclonal diversification in TNBC

Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7) rdcu.be/eFrrc

🚨Chemo treatment upgrade!🚨 Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇

If tumour genome evolution is deterministic, can we forecast genomic changes? Yes we can! At least for oncogene amps and tumour suppressor dels. @bhernando.bsky.social Angel Fernandez-Sanroman present our method for forecasting driver gene copy number change. Preprint: bit.ly/4kxF14y ⬇️1/

If you are at AACR and want to find out how we are turning chemotherapies into precision medicines, come to my talk on Tuesday! www.abstractsonline.com/pp8/#!/20273...

One more day left to apply! Come join us in our efforts to turn chemotherapy into a precision medicine.

We are hiring! Opportunity for a project manager to oversee all aspects of a multi-centre clinical research project to implement an AI-based genomic test that predicts resistance to chemotherapy - Madrid, Spain. PM for more details. Deadline 25 January! www.cnio.es/en/empleo/re...

Want to know how inherited genome instability contributes to childhood cancers? Checkout this perspective from Jayne Hehir-Kwa and me www.science.org/doi/10.1126/... on the latest brilliant work from @vanallenlab.bsky.social www.science.org/doi/10.1126/... on rare germline SVs in paediatric cancers

🚨So proud to present the first study from our @ccg-ucl.bsky.social group together with @charlesswanton.bsky.social @NnennayaKanu and led by @ojlucas.bsky.social with key collaboration @sophie-ward.bsky.social and fundamental support @rijazaidi.bsky.social @abibunkum.bsky.social & others Out now👇 🧵👇

Huge resource of MSK-IMPACT "genomes", what a treasure trove! Automated real-world data integration improves cancer outcome prediction www.nature.com/articles/s41...

Announcing the next EMBO Chromosome Segregation and Aneuploidy Meeting! Italy 2025. Please register and join us for another exciting and friendly meeting in a beautiful location meetings.embo.org/event/25-ane...