Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7) rdcu.be/eFrrc

🚀 AI in Science Fellowships – Applications Now Open! The I-X Centre for AI in Science is recruiting up to 19 fellows to join their prestigious programme and accelerate artificial intelligence research in Engineering, Natural and Mathematical Sciences. 1/5

Imperial's Schmidt AI in Science fellowships are now open! As a current fellow, I can highly recommend applying for these prestigious and enriching awards. No prior AI experience needed, just a scientific problem suited to AI. For cancer researchers there are dedicated joint positions with the ICR.

Schmidt Fellowships for #AI in #cancer research 2025 round is now open. These are pathway to independence fellowships between @icr.ac.uk & @imperialcollegeldn.bsky.social that support fellows to be competitive for faculty jobs at the end of the 2 year funding. www.imperial.ac.uk/jobs/search-...

New preprint! Let me tell you a story about trees, caterpillars, brooms, entropy, and getting scooped by 50 years. Rooted trees of all shapes and sizes crop up all over biology, computing and elsewhere. How can we best compare the shapes of these myriad trees? 1/14 arxiv.org/abs/2507.08615

Interested in population genetics of cancer? If so, have a look at our manuscript accepted by @genetics-gsa.bsky.social, in which we provide a theoretical assessment of the genetic makeup of cancers before and after treatment!

Calling data scientists: we have opening in our Data Science core @icr.ac.uk to lead work around cancer spatial biology and single cell analysis. These are staff scientist type positions, ideal for someone who wants to help drive computational research. Apply here: jobs.icr.ac.uk/vacancies/12...

If you're a PhD student interested in using maths to understand cancer, this HCEMM summer school in Szeged, Hungary, is an excellent opportunity. Registration is free and local costs are covered, so apply before 15th April.

This week-long summer school looks set to be an excellent opportunity for to learn about cancer evolution! Bursaries are available for those who require financial assistance, deadline 1st April.

Does the evolutionary history of a cancer predict patient outcome? In our new pre-print, we introduce a powerful new method to measure a cancer’s past using bulk methylation data. In chronic lymphocytic leukaemia (CLL), these inferred histories are highly prognostic! (1/9) doi.org/10.1101/2023...