I’m excited to highlight our latest paper, just published in Cell 🎉 We report the existence of a previously uncharacterized signaling pathway that is responsible for activating cell death upon loss of gene expression. 1/n 🧪 www.cell.com/cell/fulltex...

The May issue of #G3journal features work by Paltenghi and @jsvanleeuwen.bsky.social which identifies highly conserved genetic suppression mechanisms across genetically diverse yeast isolates in an effort to reduce disease severity in genetic disorders. Read more: buff.ly/AhEqx0f

The latest work of PhD student Claire Paltenghi @fbm-unil.bsky.social @unil.bsky.social @umasschan.bsky.social, on the conservation of genetic suppression interactions across genetic contexts, now published in G3 @genetics-gsa.bsky.social: doi.org/10.1093/g3jo...

<grumble> funding agencies, scoring schemes on “clarity of hypothesis” is quite a straightjacket. There is plenty of v good discovery/ hypothesis generating science which doesn’t have a “narrow” hypothesis

For those of you interested in cancer synthetic lethality, this should be a v interesting Gordon Conference organised by @mgarnett.bsky.social @vazquezf.bsky.social & Benjamin Schwartz- highly recommended ! www.grc.org/synthetic-le...

Some science news to brighten up your timelines ☀️ Our latest work on the modifiers that cause changes in gene essentiality between genetic backgrounds, now on bioRxiv: www.biorxiv.org/content/10.1... So what did we find?

We're delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases in @science.org , led by @jonaskoeppel.bsky.social , @f-raphael.bsky.social , with @proftomellis.bsky.social and George Church. www.science.org/doi/10.1126/...

Yeast Genetics & Genomics at CSHL July 22 - August 12, 2025 Application Deadline: March 31, 2025 Arrival: July 22nd by 6pm EST Departure: August 12th around 12pm EST For more info and to apply please visit the Yeast Genetics & Genomics course website: meetings.cshl.edu/courses.aspx...

📢 #Yeast2025 News! Registration and abstract submission are NOW OPEN! Join us at the 32nd ICYGMB 📅 Save the Date: 21-24 July 2025 📍 Location: Paris @sorbonne-universite.fr 🔗 Submit: premc.org/yeast2025/su... 🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...

Come join us at CSHL in March for the Network Biology meeting! Less than two weeks left to submit your abstract

Hey #networkbiology bubble and affinionados. Don't miss the CSHL Meeting: Network Biology in spring 2025. Great panel of speakers lined up by the organizers @fritzroth.bsky.social @pedrobeltrao.bsky.social, Roded Sharan, and @jsvanleeuwen.bsky.social. meetings.cshl.edu/meetings.asp...

Calling all systems and computational biologists in search of a faculty position: We have Assistant and Associate Professor positions! 🚀 Pittsburgh is beautiful, and we are doing amazing science here. cfopitt.taleo.net/careersectio... cfopitt.taleo.net/careersectio... Please apply by Dec 2!