Excited to share our new opinion piece exploring the potential of genetic suppressors—genetic variants that can rescue disease-causing mutations—as novel therapeutic targets for rare inherited diseases. Take a look here: www.cell.com/trends/genet... #RareDiseases #Therapeutics #Genetics

Now published! www.cell.com/cell-systems...

Abstract submission is open! Looking forward to seeing everyone in Pacific Grove, CA 🧬

2026 #Yeast #Genetics Meeting is 13–17 June 2026 in Pacific Grove CA. Conference website has invited speakers, abstract submission topics, preliminary schedule, etc. Bookmark the site as additional updates will be published as they become available. #YEAST26 genetics-gsa.org/yeast-2026/

Join a collaborative home of Nobel Prize-winning biomedical research. Advance discoveries of the treatment and prevention of diseases. The Morningside Graduate School of Biomedical Sciences is accepting applications for the Biomedical Sciences PhD program: direc.to/nEHU #PhD #PhDSky

I’m excited to highlight our latest paper, just published in Cell 🎉 We report the existence of a previously uncharacterized signaling pathway that is responsible for activating cell death upon loss of gene expression. 1/n 🧪 www.cell.com/cell/fulltex...

The May issue of #G3journal features work by Paltenghi and @jsvanleeuwen.bsky.social which identifies highly conserved genetic suppression mechanisms across genetically diverse yeast isolates in an effort to reduce disease severity in genetic disorders. Read more: buff.ly/AhEqx0f

The latest work of PhD student Claire Paltenghi @fbm-unil.bsky.social @unil.bsky.social @umasschan.bsky.social, on the conservation of genetic suppression interactions across genetic contexts, now published in G3 @genetics-gsa.bsky.social: doi.org/10.1093/g3jo...

<grumble> funding agencies, scoring schemes on “clarity of hypothesis” is quite a straightjacket. There is plenty of v good discovery/ hypothesis generating science which doesn’t have a “narrow” hypothesis

For those of you interested in cancer synthetic lethality, this should be a v interesting Gordon Conference organised by @mgarnett.bsky.social @vazquezf.bsky.social & Benjamin Schwartz- highly recommended ! www.grc.org/synthetic-le...

Some science news to brighten up your timelines ☀️ Our latest work on the modifiers that cause changes in gene essentiality between genetic backgrounds, now on bioRxiv: www.biorxiv.org/content/10.1... So what did we find?

We're delighted to share our work on scrambling the human genome using prime editing, repetitive elements, and recombinases in @science.org , led by @jonaskoeppel.bsky.social , @f-raphael.bsky.social , with @proftomellis.bsky.social and George Church. www.science.org/doi/10.1126/...

Yeast Genetics & Genomics at CSHL July 22 - August 12, 2025 Application Deadline: March 31, 2025 Arrival: July 22nd by 6pm EST Departure: August 12th around 12pm EST For more info and to apply please visit the Yeast Genetics & Genomics course website: meetings.cshl.edu/courses.aspx...

📢 #Yeast2025 News! Registration and abstract submission are NOW OPEN! Join us at the 32nd ICYGMB 📅 Save the Date: 21-24 July 2025 📍 Location: Paris @sorbonne-universite.fr 🔗 Submit: premc.org/yeast2025/su... 🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...

Come join us at CSHL in March for the Network Biology meeting! Less than two weeks left to submit your abstract

Hey #networkbiology bubble and affinionados. Don't miss the CSHL Meeting: Network Biology in spring 2025. Great panel of speakers lined up by the organizers @fritzroth.bsky.social @pedrobeltrao.bsky.social, Roded Sharan, and @jsvanleeuwen.bsky.social. meetings.cshl.edu/meetings.asp...

Calling all systems and computational biologists in search of a faculty position: We have Assistant and Associate Professor positions! 🚀 Pittsburgh is beautiful, and we are doing amazing science here. cfopitt.taleo.net/careersectio... cfopitt.taleo.net/careersectio... Please apply by Dec 2!