Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.

Extensive novel genetic diversity in indigenous peoples of America www.nature.com/articles/s41...

In our recent study, we created over 1000 intraspecific yeast hybrids by crossing genetically diverse strains and tested how well they grow under harsh industrial conditions such as high ethanol, salt, and organic acids. enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

Super nice story, a must 5min read communities.springernature.com/posts/why-an...

Now published! Short title could be: How to do genetics with dead things. A cross-species rescue by mating method to interrogate gene essentiality across the Saccharomyces genus doi.org/10.17912/mic...

A 50 kb bacterial genome www.nature.com/articles/s41...

Finally is the paper where we present the unique genomic architectures of the Arctic codfishes out!! Nice work by @gadus-sivus.bsky.social and co-authors … @biovitenskap.bsky.social @unioslo-cees.bsky.social link.springer.com/article/10.1...

New Covid variant has been identified and is already spreading in 25 states

I know this has circulated with alacrity recently, so you may have already seen it, but if you haven't... WOW BOY HOWDY it's the most useful thing. Thank you cardcatalogforlife.substack.com -- this is a very very very helpful public service: cardcatalogforlife.substack.com/p/google-has...

Encouraging and full of hope: this study shows that even species on the brink of extinction can regain lost genetic diversity and recover over time. www.science.org/doi/10.1126/...

Polarized growth in #Spombe needs Cdc42, but what role does it play in cell fusion? @sajjitasaha.bsky.social @sophiemartinlab.bsky.social &co show that mitotic polarized growth responds linearly to Cdc42 levels, but mating involves a sharp switch-like response @plosbiology.org 🧪 plos.io/4bvGIhb

ANNOUNCEMENT: The webpage for the upcoming yeast meetings of 2026 has recently been updated. Have a look at it to find out which exciting #yeast #conferences are ahead!!! 😀 onlinelibrary.wiley.com/page/journal...

In the latest #Yeast review article, A. Kiely, F. O'Halloran, P. Young, N. F. Lowndes, @murielgalway.bsky.social and K. Finn discuss the latest advances in understanding the versatile role of Rad9 in the DNA Damage Response in Saccharomyces cerevisiae 🧬 onlinelibrary.wiley.com/doi/10.1002/...

📢 In our new study, we identify the predominant natural route to polyploidy in S. cerevisiae. Stepwise polyploidization operates through iterative cycles of events termed "Sporulate–Endoreplicate–Mate" (SEM). Really excellent work led by @cintiagomez.bsky.social 👏 www.biorxiv.org/content/10.6...

Our paper is now out in Nature: “Ancient co-option of LTR retrotransposons as yeast centromeres” www.nature.com/articles/s41... A short thread on how retrotransposons helped give rise to yeast point centromeres. 1/14

This is a fascinating paper that reveals defined and clear mechanism for a phenomenon that for some seemed unbelievable- the up regulation of genes paralogous to those with specific types of inactivating mutations. This is called transcriptional adaptation 1/ www.science.org/doi/10.1126/...

Hello Bluesky! Does Nₑ really explain mutation rate (μ) or genome size (GS) in vertebrates? We find the apparent Nₑ–μ link in Bergeron et al. (2023) is a “back-door” path via generation time, and GS is decoupled from both Nₑ and life-history traits. www.pnas.org/doi/10.1073/... #evobio #PNAS

#Azole resistance in #Candida albicans poses a growing threat, and is linked to #StressResponse. @annaselmecki.bsky.social &co show that mutations in the oxidative stress TF Cap1 promote #DrugResistance while exposing a lethal vulnerability at high azole doses @plosbiology.org 🧪 plos.io/4rOrfOz

Check out our new review in Nature Reviews Genetics on de novo emerged genes and proteins. How they emerge, are lost and persist - and how de novo emerged proteins relate to randomized proteins! @bornberglab.bsky.social www.nature.com/articles/s41...

Excited to announce our latest publication in reporting evidence for three (3!) new whole genome duplications (WGDs) in yeasts. Scientists have often wondered why WGD is so rare in fungi, it turns out we may just not have been looking hard enough! 🧪 🍄 🧬 www.sciencedirect.com/science/arti...

Registration is open for the inaugural GRC conference in the Function of Evolving Systems. Aug 9-14, 2026, Waterville Valley. Truly stellar speaker lineup. Student/postdoc fellowships are available! Please come join us! www.grc.org/function-of-... @joybergelson.bsky.social

The deadline for the submission of papers to the special issue on the International Yeast Meetings of 2025 has been extended to 31 March. Papers should be connected to one of the meetings listed below. Hurry up and don't miss this chance! More information at: onlinelibrary.wiley.com/page/journal...

EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond. We extend our deepest condolences to his family, friends, and colleagues. www.embl.org/news/people-...

Sad to hear that Oxford Nanopore wants to discontinue the P2Solo later this year in favor of the P2i (the very pricey P2Solo that comes with a GPU to do the basecalling in it) It feels like such a big step in the wrong direction. They are a great sequencing company, not a great GPU upseller...

📣 #paper "Uncovering actionable trade-offs of antifungal resistance in a yeast pathogen" Check out our new publication in @molsystbiol.org where we systematically map stress-related trade-off associated with drug resistance in Candida glabrata (N. glabratus) link.springer.com/article/10.1...

Last paper in collaboration with Zhou XU. We explored the natural telomere length diversity in S. cerevisiae and found that ploidy level, and subtelomere structure drive telomere length variation. Higher ploidy levels lead to telomere elongation! genome.cshlp.org/content/earl...

📣 #EMBOEvoEco returns in 2026 to uncover the mechanistic foundations of ecological and evolutionary change! Keynote lectures will spotlight the ecology and evolution of symbiosis. Submit your abstract for the EMBO Workshop: https://s.embl.org/eae26-01-bl#EMBOEvoEco

Fresh news on de novo genes! Happy to present our latest work published in Nature communications: www.nature.com/articles/s41... Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)

Happy to share that the our manuscript "Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth" is now finally out in its final form @natcomms.nature.com www.nature.com/articles/s41... Below a short🧵 with the key findings!

First paper of the year for the HaploTeam, showing how domestication repeatedly reshapes sexual–asexual life cycle trade-offs in yeast, and revealing convergent evolution. Huge kudos to the team, brilliantly led by Jing Hou! www.pnas.org/doi/10.1073/...

Great paper on the genetics of facultative multicellularity in marine yeast www.nature.com/articles/s41...

Last work of the lab showing that Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution | PNAS www.pnas.org/doi/10.1073/...

📢 Join us in sunny Lisbon 🇵🇹 2-5 June for the @embo.org workshop ☀️ “The rules of the game: biophysical & molecular principles in cellular evolution” Apply by March 1st! Please repost to help spread the word! meetings.embo.org/event/26-cel... #EMBORulesOfTheGame @gimmfoundation.bsky.social

Here is our first publication of 2026 which is the first article of a special issue that mark the journal 40 anniversary - happy new year to all the #yeast community

The new year has just started and we are happy to share the news that the new issue of #Yeast (Volume 42, Number 12, December 2025) is finally out!!! 😀😀😀 This issue includes two research articles and two reviews. You can browse it at this link: onlinelibrary.wiley.com/toc/10970061...

Extinction rarely departs with drama, it slips out the back door while we’re still debating the guest list. These records are made official on the Red List. "Conservation failures are often recognised only once they can no longer be reversed." via @mongabay.com: news.mongabay.com/short-articl...

As many of us 🎁 things up for the year, make sure all your ℹ️'s are dotted- and all your #yeast emojis are downloaded! If you haven't yet, make sure to add the emojyeast collection to all your 📱💻🖥️⌚️ mayaschuldiner.wixsite.com/schuldinerla... Thanks to the amazing Schuldiner lab for these!

New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...

www.pnas.org/doi/10.1073/... #MicroSky

When colonizing a new habitat, organisms adapt to maximize their reproductive success via #LifeHistory #evolution. @ecoevodevolab.bsky.social @cbank.bsky.social show that life history evolution facilitates niche diversification across a range of theoretical models @plosbiology.org 🧪 plos.io/4p7YT0a

In the latest #Yeast research article, Miguel A. Rocha, Gowda Bhavani and Jacob Fleischmann investigate the role of exonuclease-resistant ribosomal RNAs in Saccharomyces cerevisiae, their relationship with nutritional status and the TOR signalling pathway. onlinelibrary.wiley.com/doi/10.1002/...

Nouvelle vidéo 🎉 Pourquoi le prix Nobel de physique 2024 concernait l'I.A. ? Comment sont nés les réseaux de neurones ? Quel est le lien avec les champs quantiques ? Toutes ces réponses en 13 minutes ⤵️ youtu.be/2kbAId70b_I

Independently evolved supergenes control colony social organization and queen reproductive strategies in several ant lineages. Sigeman et al. uncover a novel 9 Mb supergene controlling queen size and social organization in Myrmica ruginodis. 🔗 doi.org/10.1093/molbev/msaf255 #evobio #molbio #ants