We’re excited to introduce scCHyMErA-Seq, a scalable #CRISPR-based #exon-deletion screening platform with #single-cell transcriptomic readouts, enabling high-throughput functional analysis of #alternative #splicing. In collaboration with the Gonatopoulos-Pournatzis lab. @natcomms.nature.com

Check out the latest paper from the Gonatopoulos-Pournatzis lab using CRASP-seq, an RNA-coupled #CRISPR screening platform, to uncover novel #splicing regulators.

www.nature.com/articles/s41... A collaborative project incepted by Michael Kosicki, and executed by Ananth Pallaseni (both Ph.D students at @sangerinstitute.bsky.social at the time) and Elin-Madli Peets.