Michael Aregger (@michaelaregger.bsky.social)

The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations - Nature Communications Here the authors measure how the absence of certain DNA repair genes change the frequencies of unique mutational outcomes generated by Cas9 DSBs at synthetic target sequences in mouse embryonic stem c... https://www.nature.com/articles/s41467-024-54566-7