Pathologists have used nuclear & tissue shapes to diagnose #cancer for decades, but what is the molecular basis for this? In our latest work, we develop a computational pipeline to figure this out in #colorectalcancer! Check out 🧵& preprint #mechanobiology #stemcells www.biorxiv.org/content/10.1...

Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis pubs.aip.org/aip/apb/arti...

We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum. First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social rdcu.be/ezBl7

Congratulations to Thomas Callister, Peter Lu (@petery.lu), Aditya Nandy, Ludwig Schneider, Shailaja Seetharaman (@sseethar.bsky.social), Colm Talbot, Madeleine Torcasso, and Yihang Wang!

Final presentations for Physiology 2025 were last weekend; the students did an awesome job. @sseethar.bsky.social, @andyletzhang.bsky.social, @squishycell.bsky.social, and I were all very proud 🤩.

Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com

The first objective of IMBA is to make its scientists successful. Let us help you turn ideas into discovery! IMBA is hiring a Junior Group Leader in the molecular life sciences. Apply below. #hiring #biology #research #groupleader #europe

🌿✨ Calling all mechanobiologists, bioengineers, and curious minds! ✨🌿 Join us in Vietnam this year for an unforgettable Conference on Mechanobiology, where science meets culture in one of Southeast Asia’s most vibrant destinations. 📅 06-12 July 📍 Quy Nhon, Vietnam 🔗 icisequynhon.com/conferences/...

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

Join us Friday April 11 for talks by David Hathcock @davidhathcock.bsky.social (Mechanisms for dissipation-enhanced adaptation & cooperative sensing in bacterial chemotaxis) & Shailaja Seetharaman @sseethar.bsky.social (Mechanosensitive LIM domain protein FHL2 tunes endothelial function) #biophysics

Awesome work showing a super clean + thoughtful application of using genomic deep learning models for discovery. Interpreting regulatory mechanisms of Hippo signaling through a deep learning sequence model www.cell.com/cell-genomic...

IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.

Mike Sheetz (1946-2025) made immense contributions to our understanding of motor proteins, membrane biology, cytoskeleton and mechanobiology. Haguy Wolfenson, Gregory Giannone, and Martin Schwartz recall his life and work: rupress.org/jcb/article/...

How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪 Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻 🧵 @cp-immunity.bsky.social www.cell.com/immunity/ful...

Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...

Looking for EGFR shrna plasmid urgently if someone has it🙏 if you could please check your connections it would be great as well! Thank you

As scientist I am going through difficult times (this is understatement of the year for me!!). Past one and half months have been horrible, however I am trying to pick myself up and super excited to share my postdoc work with the community! #cellmigration www.biorxiv.org/content/10.1...

Hot from the press: #CellMigration #vesicles #organelles Jeppesen et al @mag2art.bsky.social lab introduce blebbisomes: organelle-rich motile vesicles, have immune checkpoint inhibitors, released by #cancer cells & used for #cellcomm @naturecellbiology.bsky.social www.nature.com/articles/s41... 🧪🔬

New preprint out 🔥🔥 on my postdoc work with @manuelthery.bsky.social and @lblanchoin.bsky.social about how we can create sustained dynamic steady states of actin network inside microscopic wells that contract "forever" without collapsing! A thread 🧵 www.biorxiv.org/content/10.1...