"Our real duty as teachers has always been challenging students to think. The task now is finding ways to engage them in the painful, essential work of critical thinking in a world where machines are willing to do it for them." #ScienceWorkingLife https://scim.ag/4vKqh8k

This paper is worth it for table 1 alone. 👏 @sabinehoffmann11.bsky.social @boulesteixlaure.bsky.social et al onlinelibrary.wiley.com/doi/10.1002/...

Paying peer reviewers Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review Spoiler: it works - fast, high quality reviews www.nature.com/articles/d41...

Our new preprint 'NucleiSky enables cross-scale multimodal registration of microscopy data using nuclei constellations' is out! 🎉Check out @guijacquemet.bsky.social post first to learn more🤩 In this 🧵 I’ll share how we used NucleiSky in smart microscopy and how you can install and try it yourself 👇

ICYMI: New online! Actin cytoskeletal dynamics in hepatic myofibroblasts and fibrosis

🧬 Figure Friday What role does magnesium play in important cancer proteins? Thomas E. Wales and colleagues show that Mg²⁺ acts as a structural gatekeeper for KRAS, helping control its shape and activity while revealing new opportunities for drug development. #FigureFriday #ProteinScience #KRAS

@odedrechavi.bsky.social hi I tried the Q.E.D tool and found the results interesting and informative. However, if I got this right it only highlights weaknesses? I think it would also be useful to annotate strengths? I may well have missed this though.

for example i have identified a preprint that isn't found using .com but is using .co.uk Any ideas? I'm logged into both with the same account #googlescholar

Any one else noticing that Google Scholar doesn't work as well as it used to? I've noticed that it doesn't find articles as quickly as it used to i.e. papers can now be in pubmed before scholar. I also wonder if there is a difference between scholar.google.co.uk and scholar.google.com

"the first validated, large-scale framework for judging the quality of life science papers independently of venue, identity, and prestige...Blinded domain-expert professors sided with score three times more often than with journal rank" the-one-percent.qedscience.com 1/n

Of particular interest (I thought) was the fact that oscillatory and elevated shear stress have distinct impacts on production of alternative RNA isoforms - including those coding for the integrin adhesome proteins PDLIM5 and SORBS3 (vinexin) [see figure 4]

Congrats and thanks to Steve White and everyone @martinhumphries.bsky.social who contributed to this work. Really pleased to have been able to make a contribution.

Multiomic Reference Map of Endothelial Mechanosensitive Pathways Under Athero- and Erosion-Prone Flow www.ahajournals.org/doi/10.1161/...

Inactive β1-integrin acts as a junctional scaffold for angiopoietin/TIE2/FOXO1 signaling www.jci.org/articles/vie...

Fibrillin-1 inhibits early adipogenic commitment via αvβ3 integrin signaling www.sciencedirect.com/science/arti...

Diffusing caveolin-1 scaffolds regulate mechanosignalling www.nature.com/articles/s41...

Wonderful news! #VaccinesWork Cervical cancer deaths fall to zero in young women given vaccine www.bbc.co.uk/news/article...

How do donated tissue samples help shape future cancer treatments? Our latest blog explores the work of the MCRC Biobank, which has collected more than 230,000 samples from nearly 30,000 patients to support cutting-edge cancer research. Read more: https://ow.ly/ozuS50Z5EsS

There's probably never been a better time to remind you that when David Hockney first took his Mum to California she remarked 'all this lovely weather and nobody puts their washing out'.

Dynamic Time-Resolved Remodeling of the Immune Microenvironment After Resistance to BRAF/MEK Inhibitors in Melanoma: Mechanisms, Biomarkers, and Emerging Therapeutic Strategies www.mdpi.com/1422-0067/27...

Mechanobiology of cancer-associated thrombosis: from molecular mechanisms to therapeutic innovation link.springer.com/article/10.1...

Pan-cancer atlas of ITGA6 unveils its multifaceted oncogenic roles and therapeutic potential in uveal melanoma link.springer.com/article/10.1...

TurboID-Based Proximity Labeling Map Reveals the Protein Interaction Network and Anti-Viral Mechanism Against Influenza A H1N1 faseb.onlinelibrary.wiley.com/doi/10.1096/...

Adhesion-derived condensates control component availability to regulate adhesion dynamics www.nature.com/articles/s41...

🔬 Exciting progress in melanoma research. Researchers have announced promising long-term results from a study investigating a personalised mRNA cancer vaccine for people with high-risk melanoma. (1/5)

Very excited to be sharing our new paper, just out in Nature Cell Biology! The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?

In their Cell Science at a Glance article, @zeinabrekad.bsky.social Stavroula Mili, Ellen Van Obberghen-Schilling & Delphine Ciais highlight the ways in which RBPs & local RNA regulation impact adhesion-dependent processes, & the effect of their dysregulation. journals.biologists.com/jcs/article/...

Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma

RING1 is an Integrin α5 E3 ubiquitin ligase and inhibits esophageal squamous cell carcinoma cell migration and metastasis www.sciencedirect.com/science/arti...

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

The review is an at glance style paper, that I proudly took some time to illustrate and @jcellsci.bsky.social design team beautified 😍. Have a look, and you might be pleasantly surprised to find how your favorite #RBP directly supports cell adhesion!

Alright, I am pausing my social media break to share with you the final review of my PhD erra (times fly by 🥲). Featuring 2 of my favorite science fields: #RNAbiology and #celladhesion 😍. Also a fantastic collab with one of my top #women_in_sci role models: Stavroula Mili 💙

Pan-cancer analysis reveals Rho kinase addiction as a vulnerability of de-differentiated cancer cells www.cell.com/iscience/ful...

Slow but steady: Molecular mechanisms controlling #microtubule growth in #centrioles and #cilia. New review from Saishree S. Iyer and Anna Akhmanova @utrechtuniversity.bsky.social: rupress.org/jcb/article/... #Biochemistry #Cytoskeleton

I am delighted to be able to share that our latest paper arising from a project co-led by @drsarahboyle.bsky.social and me is now out in the world, published in AAAS Science Advances. www.science.org/doi/10.1126/...

Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory | Science Advances www.science.org/doi/10.1126/...

CCDC66 couples actin-microtubule crosslinking to KANK1-associated microtubule targeting and focal adhesion turnover https://www.biorxiv.org/content/10.64898/2026.05.19.723697v1

Sensing of shear stress in vascular endothelial cells – from physiology to pathology journals.biologists.com/jcs/article/...

Dame Bridget Ogilvie obituary www.theguardian.com/science/2026...

In collaboration with the TransCODE consortium, EMBL-EBI scientists have found over 1,700 new proteins in the ‘dark proteome,’ a region of the human genome once thought to be noncoding. These new proteins could have implications for human diseases, including cancer. tinyurl.com/yc4t6s3s

USP40 protects podocytes by deubiquitylating integrin β1 www.sciencedirect.com/science/arti...

AAK1-mediated phosphorylation of PDLIM5 and Talin1 promotes focal adhesion disassembly to accelerate cell migration www.nature.com/articles/s41...

UNC5B activates hepatic stellate cells and promotes liver fibrosis via FAK link.springer.com/article/10.1...

This puts it in perspective: the importance of higher education for the economy of a place like Manchester.

Researchers at the Crick and @imperialnhli.bsky.social have discovered that mice with a cold virus infection were less susceptible to the spread of breast cancer cells into their lungs. www.crick.ac.uk/news/2026-04...

Slingshot-1 (SSH1) phosphatase Controls Cytoskeletal Remodeling, Integrin conformation and Metabolic Reprogramming During CD4 T Cell Activation www.researchsquare.com/article/rs-8...

Discovery of actinators, actin-derived bioactive peptides that modulate cytoskeleton and actin-related cellular activities www.science.org/doi/full/10....