“As scientists, it is our responsibility to communicate to the citizens of our nation so that we can work together to ensure their health and the health of their children.” - Lucy Shapiro, #LaskerAward winner 🧪 #Lasker2025 #scicomm @JAMA.com

Our latest manuscript is out, and this one tackles the problem of cellular aging in the retina, using comparative multiomic analysis of zebrafish, mouse, and humans. What led us to work on aging after studying development and regeneration? Explainer follows./1 www.biorxiv.org/content/10.1...

Why are low-complexity domains (LCDs) in proteins important? #LaskerAward winners Dirk Görlich & Steven McKnight showed that they are critical for intracellular transport and organization. #Lasker2025 #structuralbiology #phaseseparation @mpi-nat.bsky.social

Thrilled to share our latest work from my fantastic postdoc fellow Dr. Emilio Méndez-Olivos: Pdgfab/Pdgfra-mediated chemoattraction guides the migration of sclerotome-derived fibroblast precursors in zebrafish, now published in @plosbiology.org! 1/8 dx.plos.org/10.1371/jour...

This year's Lasker Awards went to scientists who studied the wiring diagram of life, a new state of biological matter, and a potent treatment for cystic fibrosis. Here's my story with Gina Kolata. Gift link: nyti.ms/4mZlH1F

New preprint! How are developmental cycles coordinated across cell types? It turns out that, like Geppetto's cuckoo clocks in the GIF below, individual cell types are each performing their own little crazy routine, but all in sync with each other.

Join us Sept 10 at 12 PM CST for #WebinarWednesday with the ORS Preclinical Models Section. Learn how large & small animal models advance #tendonresearch and why choosing the right model depends on your research question. Free for ORS members. Register here: https://t.co/TcbSCLEWOo

Register now for an ORS Tendon Section #WebinarWednesday on Sept 24, 12 PM CST, A Tendon-cy to Heal: Regenerating Tendons & Ligaments in Zebrafish. Hear from Thomas Schilling, Jenna Galloway & Joanna Smeeton on the latest #tendon & ligament regeneration. 🔗 ors.memberclicks.net/ten092425web#/

1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature - www.nature.com/articles/s41...

Fantastic coverage of our recent work in Nature. Thanks!!!!

Some more information on M-AB can be found here and the fish are available from the National Institute of Genetics in Japan after signing an MTA (we have them in our facility and they are growing happily):

#zebrafish genome update, our T2T assembly of the inbred strain of AB (M-AB) generated by my buddy Nori Sakai has now been released at NCBI and will be a second reference genome for zebrafish (GRCz12ab):

"The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades." 4000 labs is a severe understatement, likely off by an order of magnitude. Even non-fly people use and benefit from FlyBase. It is one of the cornerstones of the genome era.

🧪 Senate appropriators say: NIH's budget gets a... boost! Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%). "Congress has your back," said @murray.senate.gov. ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.

Dr. Ben Barres was a passionate investigator, a dedicated professor, and a prolific mentor. His authenticity and commitment made a lasting impact on the scientific community. Read more about his incredible legacy here 👉https://ow.ly/YRWM50Wapn6 #Anatomy26 #AAA

Hello world! Happy to announce that your favorite society section has arrived on Bluesky. Excited to interact with you all here 😁 Use #teamtendon to keep connected when making posts about your favorite tissue!

Beyond the bare bones of the skeletal gene regulatory network Read this Research Highlight showcasing work from Patsy Gómez-Picos, Katie Ovens, Amir M. Ashique, B. Frank Eames and colleagues: journals.biologists.com/dev/article/...

Thrilled that my blog post was the most-read hit on the Node for the month of May ☺️ It acts as an intro to the amazing tools that are (freely) available to #zebrafish researchers. Do check it out if you haven’t yet. 🔗 thenode.biologists.com/bioinformati...

Hello Fly Folks. quick note FlyBase is under duress due to termination NIH$ to Harvard and intl collabs. The hardworking folks @flybase.bsky.social are doing their darndest to ensure access to current data. For US, there will soon be a new site to donate. Please spread the word, ideas and support 🪰💪

Congratulations to our prize winners! Best undergrad poster: Lauren Choy (Galloway Lab). Best grad student poster: Brittney Love (North Lab). Best post doc poster: Morgan Walcheck (North Lab). Best undergrad/grad student talk: Felicia Wranitz (Burns Lab). Best post doc talk: Lu Yue (Zon Lab)

Thank you to everyone who participated in the 2025 Boston Area Zebrafish Researchers Meeting! You all made this a fantastic meeting!

1) Despite the chaos, I am very pleased to present the terrific research conducted by my post-doc @clarissacoveney.bsky.social. acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

Cross-posting from LinkedIn: www.linkedin.com/posts/kevin-... These are useful (and free!) websites that I found in my search for all things #zebrafish as part of my Bioinformatics Bootcamp. If there’s enough interest, I may do a blog post on the Node. Enjoy!

Delighted to share this timely article in Boston magazine on our local C. elegans community and the effects of NIH freezes. "There might be no group more enthusiastic, self-aware, or life-affirming than the worm people." www.bostonmagazine.com/news/c-elega...

Good luck KJ!! Their work — kept secret until now — is likely the fastest-ever creation of a new drug, and the first time that any patient has received a truly bespoke gene editing treatment to fix the root cause of their disease. endpts.com/philadelphia...

ATTENTION New crowdsourced site collecting and sharing stories of public impact of research publicusaresearchbenefits.com Take a look and consider contributing. Let's make this as powerful as possible!

Fibroblasts & endothelial cells appear to orchestrate the early response to injury in ruptured quads tendons. Great to see this published in & congratulations to @joletmimpen.bsky.social & the rest of the team. physoc.onlinelibrary.wiley.com/doi/10.1113/...

I'm thrilled to share that my grant proposal with @jennagalloway.bsky.social, based on my postdoc research, was funded by the ON Foundation! This #orthoregeneration project stems from years of NIH-funded basic science studies leveraging the adult zebrafish as a potent regenerative organism 🐟🧫

Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1 www.biorxiv.org/content/10.1...

Proud of my undergraduate student Ella in @jennagalloway.bsky.social’s lab on giving an excellent talk at the Center for Musculoskeletal Research (CSR) Symposium earlier today! Sad that I couldn’t attend it, but I’m happy to hear from others that her first talk was very well-received!

April 18, 2025 open.substack.com/pub/heatherc...

Proud (but bittersweet) mentor moment — watching my student, Ella, practice her first research talk! She’ll be representing the @jennagalloway.bsky.social lab at the upcoming MGH Center for Skeletal Research Symposium. The only undergraduate giving a talk! 🥳🐟

Jim O'Reilly asked a really neat question at lunch that turned into this exploration of the evolution of body wall muscles in amphibians. The three groups jump (frogs), walk (salamanders), and undulate (caecilians) so the variation is extreme. 🧪 www.researchgate.net/publication/...

Harvard redid its whole homepage to push back against the administration’s demands. I mean, this is just a website but I think it’s kind of a great PR move: www.harvard.edu

Breaking: Harvard's response to the government's threat of withholding research grants to exert control over universities 👇 Research grants are not political weapons. The stakes are not abstract: Every $ withheld is a delayed cure, a patient or family left behind. www.harvard.edu/research-fun...

12 examples of how developmental biology research led to fundamental discoveries for biomedical research. There are many more! Download ppt & jpg versions on @socdevbio.bsky.social website. Use & modify as needed. Poster formats are also posted to print & hang in your lab!

NIEHS - 22 April, to be published tomorrow (public-inspection.federalregister.gov/2025-05015.pdf) NINDS - 10 April, to be published tomorrow (public-inspection.federalregister.gov/2025-05025.pdf) NIAMSD - 21 April, to be published tomorrow (public-inspection.federalregister.gov/2025-04968.pdf)

Some #zebrafish news. After consulting with the Genome Reference Consortium (GRC) we will annotate one of our Tübingen T2T assemblies as a reference genome. This is an excellent assembly that we can get into the hands of the zebrafish research community right now. We are continuing our efforts

Call your representatives right now. EPA's research arms provides essential function and ensures that we are safe from toxic exposures. www.nytimes.com/2025/03/17/c...

A good column about Latrobe, PA's favorite son Fred Rogers and what he would have thought about the Trump administration. www.post-gazette.com/opinion/insi... 1/3

Congratulations to Ella, my mentee in the @jennagalloway.bsky.social Lab, being accepted to the prestigious Herchel Smith Undergraduate Science Research Program! Ella also received a Spring 2025 HCRP Award for her project studying immune/mechanical crosstalk during adult enthesis regeneration 🐟

99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...

Bluetorial: Women, courage, and leadership What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.

The 2025 Boston Area Zebrafish Researchers (BAZaR) Meeting will be held at Boston College on Friday May 30, 9am-5pm. More information coming soon! #ZebrafishMeeting #Zebrafish

When did synovial joints evolve? @neelimasharma.bsky.social @neilshubin.bsky.social &co reveal that stable, mobile & lubricated joints were present in the common ancestor of jawed fishes but lacking in jawless ones 🧪 @plosbiology.org plos.io/3CTC8La

I have been trying to find the time to move away from the polical hellscape we find ourselves in to finish and share a bluetorial about science. This helps me remember what this is all about. Ironically, it is about the treatment of pain.

New York Times article now up on Federal Register stuff. www.nytimes.com/2025/02/21/s... 1/n

Critical reading here from the @socdevbio.bsky.social. And remember, the overall spending freeze was lifted but NIH operations are still paused. Lots of work still to do.

If you’re in the US and you’d like to know what projects and vital services federal grants currently fund in your state, you can search here: www.usaspending.gov And you can find the contact information for your elected representatives here: www.usa.gov/elected-offi... They need to hear from you.

I'm one of these 11,965, and with funding from the NIH and NSF, I've been able to recruit several more full-time employees to MI (many coming from other states!) since 2023. @repdingell.bsky.social, please advocate for us in science, health, and research to continue supporting the michigan economy