New preprint showing Adgrg6 and Sox9 genetically interact, increasing the penetrance and severity of scoliosis in mice and that Adgrg6-Sox9 signaling works through a self-reinforcing feedforward circuit to maintain ECM expression in connective tissues of the spine. www.biorxiv.org/content/10.6...

Alright bone aficionados! The 2026 Lawrence Family Bone Disease Program of Texas program is planned, with keynote: Dr. Mone Zaidi. Attendance is free, but registration is mandatory. txbonediseaseprogram.org/index.php/an...

St. Louis folks I’ll be giving a talk 2:20pm as part of the Diane Sepich Memorial Symposium At the Fort Neuroscience Auditorium WASHU med campus, on our work to automate the detection and quantification of cilia morphodynamics and implications on scoliosis. @wu-ciliopathygroup.bsky.social

Our newest work on quantification and statistical testing of scoliosis severity using microCT and R. www.cell.com/star-protoco... Thanks to @eceatayeter.bsky.social @brittneyvoigt

Great collaboration with Dan Cohn's group showing that small molecule inhibition of Trpv4 can rescue skeletal dysplasia of Trpv4 mutant mice. pubmed.ncbi.nlm.nih.gov/41574606/

20th annual @jbwallingford.bsky.social lab chili cookoff 🌶️ previlaged to be part of a few along the way. Congratulations to the top chili winner Ty Gardner!

Our new work Cilia.io is out on the Rxiv. Ece Atayeter and Jason Ho trained an ML computer vision transformer for detection and quantification of cilia morphology and dynamics. We will provide a GUI soon. Another great collaboration w/ @jbwallingford.bsky.social

Congratulations to the newly minted Dr. Brittney Voigt! After defending a fantastic thesis spanning work in my lab and the @edwardmarcotte.bsky.social lab.

As Vice Chair of the GRC Bones and Teeth, I am delighted to invite you to join us for our upcoming meeting, on January 25–30, 2026, at Hotel Galvez in Galveston, TX, a cherished venue for our conference. We look forward to welcoming you to what is sure to be an exciting and memorable meeting!

Mr Kevin ‘shiny ribs’ Russell at Wyldwood

New music Friday. @leifvollebekk.bsky.social is incredible. Highly recommend. Can’t wait to see you in the ATX in November.

Fun times with friends

Slightly diminish a band: the Meh Dead

Slightly diminish a band: U1

Today was a good day…

Cool new paper on the role of cilia in postnatal pituitary development.

Great new paper showing that human AIS may be in part modeled as a sub-clinical neuromuscular disorder. pubmed.ncbi.nlm.nih.gov/40662934/

Happy to be reviewing NIH training grants today. Let’s hope this continues for us all.

RFK Jr. should be jailed. This is all on him. Vaccines work. Measles Cases Hit Record High, 25 Years After U.S. Eliminated the Disease www.nytimes.com/2025/07/09/w...

After the floods the frog are ready

Bigstar was a grwat band. Thats all thats the tweet. music.apple.com/us/album/my-...

Cilia Alert! So excited to finally have this paper on the CPLANE complex out in @natcomms.nature.com! We show that RSG1 is a human ciliopathy protein and links CPLANE to the transition zone. 1/n www.nature.com/articles/s41...

Look at this handsome son of a gun.

nothing like bringing a new technique to the lab, RNAScope Soxx9 (red) in P40 mouse tibia.

Great resource thanks Jeff et al!

If you love Daniocell, but wish it could generate analyses specific to YOUR genes & cell types of interest, check out DaniocellDesktop - a new point-and-click app for Mac and Windows that enables reanalysis of the Daniocell data without programming: daniocell.nichd.nih.gov/desktop/ (1/4)

RIP Brian Wilson. Thanks for the music. Here is my favorite of his. music.apple.com/us/album/lov...

foxj1a:Arl13B-GFP labeled cilia lining the anterior spinal canal, above the notochord.

FYI when writing someone to request a job interview you might want to included a more concise sentence on why you want to work with them instead of this: ' I have recently reviewed your research which really interests me in your field of activity'. Form letters do not work.

Somedays you wake up and choose Bad Brains.

Great collection of informics websites. Thanks @kevinthiessen.bsky.social !

I miss ticket stubs…also I cannot believe this was 30+ years ago

Happy Mothers Day to all those that celebrate. youtu.be/BKpd0l-O77U?...

"Four legs good, two legs bad." Welcome to the twilight zone.

Has anyone ever modeled myocardial infarction in zebrafish? Genetically or via ligation? Asking for a colleague.

Khruangbin at the Moody

Just saw Pink Floyd Live at Pompeii at the @alamodrafthouse.bsky.social . It’s been a while but still holds up as one of the best Rock docs ever.

Better late than never I guess…

Had a wonderful meeting at Dallas Scottish Rite for Children. Thank you to the NIH/NICHD P01HD084387 award for supporting our collective research in adolescent idiopathic scoliosis.

www.kut.org/science/2025... Great cast on the importance of science research and the dangers of cutting funding. Highlighting @jbwallingford.bsky.social and @mclellanlab.bsky.social labs at @utaustin.bsky.social

While I wish I could just put my head down and work, at this time Trump is defining the Supreme courts ruling to bring back prisoners illegally moved to a foreign gulag. We resist or our constitutional republic is no more. People in the streets is the only way I know how. youtu.be/dF1tWRtzJ8Q?...

Caught ya!

I’m pretty sure that all of lives problems would be solved if more people would just push out the jive and embrace the funk. youtu.be/QrgV35cBHVs?...

Finally out! Brittney Voigt et al show the shared role of Inppl1a expansion of notochord vacuolated cells and also for hypertrophy of chondorcytes and bone lengthening. @currentbiology.bsky.social www.cell.com/current-biol...

What a baller! Sorry but it’s @booker.senate.gov for President or bust. Except no substitutes. www.nytimes.com/2025/04/01/u...

Happy proofs day for all those that celebrate.

People in the streets

This situation feels like the boiling frog analogy, and we are the frogs, but at some point we may all choose to be the water. #peopleinthestreets