When to target the most abundant protein in the heart? @droch.bsky.social & team show myosin becomes maladaptive in X-linked myotubular myopathy, consuming excessive energy, and inhibiting its ATPase activity in mice partly rescues the molecular defects: doi.org/10.1172/jci....

Our team at Københavns Universitet - University of Copenhagen will soon be looking for a postdoc with experience in AI-driven vHTS and cardiac sarcomere modeling. If interested please send me an email. Spread the word :-)

Great collaborative work led by Christopher Toepfer and his team at the University of Oxford

We are recruiting a Reader/Professor of Immunobiology at @kingslsm.bsky.social . This is a unique opportunity to shape basic immunology at @kingscollegelondon.bsky.social . Please RP. www.kcl.ac.uk/jobs/131447-...

Top selling from pharma companies

Our collaborative effort unravelled puzzling results warranted more research on the topic of myosin and cardiac chamber specificities @ucph.bsky.social

Excited to present our recent work on myosin as a molecular target for genetic muscle diseases! Kudos to all authors, especially Elise, Fanny and @myofinlab.bsky.social @ucph.bsky.social

Asterix and/et Ozempix

Recruiting a comp PDRA for the lab 🚨 Working on multiple projects using integrated multi omics in bulk & single cell level Passion for data, coding, bioinformatics & keen to lead our labs comp workflow 12 months in first instance but extendable for further 19 months my.corehr.com/pls/coreport...

Multilingualism protects against accelerated aging www.nature.com/articles/s43...

We will soon be looking for a comp biologist or bioinformatician to work on a number of linked projects within the lab - main focus is on molecular control of muscle Before the official advert is published, I’m hoping to spread the news to any talented near-finishing PhDs or keen postdocs!

We are grateful to Independent Research Fund Denmark for funding our new project aiming to understand and treat heart failure! The project will take place at @ucph.bsky.social

Ensure #ISHLT2026 will be next level. ▶️ Submit your science in the treatment of advanced #heart and #lung disease, #transplantation, #MCS, and #PVD by 📆 14 October: 🔗 https://bit.ly/4dLYGdn

We are looking for an enthusiastic MD or PhD to work on a postdoc project on the molecular mechanisms underlying human hibernating myocardium and ischemic cardiomyopathy. If interested send me an email! #heart #cardiomyopathy #sarcomere

🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important Good collab with @droch.bsky.social so travel to CPH involved as well www.kcl.ac.uk/jobs/126245-...

This trial has been stopped for strategic business reasons

Postdoc opportunity in muscle cell biology! You would not only be involved in an ambitious project but would also help develop cutting edge methods! Highly recommended! @robertseaborne.bsky.social

UAB and Children's of AL is looking for a new Division Director of Pediatric Neurology (come be one of my bosses!). We are consistently in the top 30 nationwide in Pediatric Neurology and have excellent subspecialties in: Epilepsy, Autism, and NMDs. Apply: tinyurl.com/y8d8duve

Please repost! We have an open rank, tenure-line faculty position in biomechanics in the School of Kinesiology at the University of Michigan Ann Arbor. At U-M we have great colleagues, exceptional resources, and biomechanics can be found all across the campus. #BiomechSky

Such a great city for science and culture 🇨🇦💕

Very happy to have been awarded a NIRG from the MRC. Stay tuned for some exciting (I think, but being biased) postdoc positions within our lab!

What is the proportion of HFrEF and HFpEF patients with CKD? #cardiosky

Application submitted to @novo-nordisk.bsky.social - 🤞 - on to next one now!

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...

We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social

Interested in nuclear #mechanobiology? Join us for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC. Find more information and register at: events.faseb.org/event/Mechan... Submit abstracts by August 31, 2025. Please share and see you in October!

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

Our department @ucph.bsky.social is looking for a new faculty member! This is a nice environment for an ambitious PI with a research focus on cardiovascular system, metabolism and/or drug discovery! Happy to answer questions if you are interested!

Damien M. Callahan presents this #TranslationalPerspective on the work of Laitila et al. linking altered structure and post-translational modification of Troponin T to dystonia in nemaline myopathies💭 ✍️ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...

Looking for a #LifeSciences postdoctoral #opportunity? 🧪 Have a look at the EMBO Postdoctoral Fellowships for internationally mobile scientists in #Europe and globally. Apply before 11 July: www.embo.org/funding/fell... #research #funding #postdoc

Save the date! On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility news.ki.se/ki-to-recruit-junior-researchers-with-a-focus-on-excellence

Check out our comprehensive review on #metabolism in #hypertrophiccardiomyopathy! Now published online in the Journal of Cardiovascular Aging

Great review article on metabolism and HCM led by @edgarnollet.bsky.social #cardiosky

Last chance to register (attend online or in person) and/or submit an abstract to @sma-europe.bsky.social 1st International Clinical Care. Deadline is June 15th! Registration: na.eventscloud.com/ereg/newreg.... Abstract submission: na.eventscloud.com/eSites/sma20...

Registration for the Joslin Diabetes Symposium 2025 is now open. Focus is on inter-organ and international communication and the event is supported by friends in Canada and Denmark (Steno-DK)! 🇫🇴🇨🇦🇺🇸🇬🇱🇩🇰 More info 👇 @novonordisk.bsky.social #Steno-DK #Joslin #Toronto joslinsymposium.org

Offre de stage Master 2 @ucph.bsky.social dans le domaine des maladies cardiaques #CardioSky

Thrilled to share that our manuscript mapping proteomic & phosphoproteomic signatures of NGT, T2D, males & females — before and after hyperinsulinemic-euglycemic clamp — is now accepted in Cell. @annakrook.bsky.social @juleenrzierath.bsky.social @cbmr.science doi.org/10.1016/j.ce...

Great study - just showing the title for others.

Very enjoyable collaboration with puzzling results on myosin and HCM @ucph.bsky.social @amsterdamumc.bsky.social @novo-nordisk.bsky.social

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social www.science.org/doi/epdf/10....

Excited to see (newly Dr) Greg Milburn's paper on cardiac amyloidosis in human myocardium with cell-level mechanics, histology, and gel-based analysis of sarcomeric proteins. Myocardium From Patients With ATTR Amyloidosis Produces Less Force Secondary to Increased Fibrosis doi.org/10.1016/j.ja...

The most abundant skeletal muscle protein (myosin) becomes super-relaxed and energy-efficient in type 2 diabetes mellitus #T2D #DiabetesResearch link.springer.com/article/10.1... 🔓

Come join us at @westernuresearch.bsky.social as a Canada Excellence Research Chair! DM me with questions/interest about theme 2! Be a part of a strong and well-equipped (e.g., imaging, behaviour) neuroscience community! uwo.ca/research/cer... @westernuwin.bsky.social @westernubrainscan.bsky.social

We have 2 new very collaborative papers where we get a better understanding of the molecular mechanisms of myopathies due to sarcomeric mutations. 🙏🙏🙏 to all authors and @novo-nordisk.bsky.social physoc.onlinelibrary.wiley.com/doi/10.1113/... physoc.onlinelibrary.wiley.com/doi/10.1113/...

Integrated single-cell functional-proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof-of-principle study Another collab between the labs @droch.bsky.social @adeshmukh.bsky.social physoc.onlinelibrary.wiley.com/doi/10.1113/...

New collaborative paper from @droch.bsky.social group, combining SkM biopsy, single fascicle and single myofiber biophysical and molecular experiments in T2DM link.springer.com/article/10.1...

I am happy to have contributed to this exciting work by applying our single muscle fiber proteomics workflow.

Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus link.springer.com/article/10.1...