A recent study by Amber Mills et al. examines #nicotine influence on #cerebrovascular and #neurocognitive function with in utero electronic cigarette exposure 🚬 🧠 📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Indira M. Raman & Carl D. Hopkins investigated high-frequency electrical tuning and linear filter properties of Knollenorgan #electroreceptors of mormyrid electric fish 🐟 ⚡ 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this recent #Technique article, Matthew D. Lee et al. outline the use of #VasoTracker2 as an open-source software and hardware for tracking blood vessel diameter and assessing #vascular function 💻 🫀 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Alexis Ruiz of unibas.ch et al. finds that massive reduction of RyR1 in #muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes #scoliosis 🔬 🔎 📜 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this study, David C. Andrade et al. observed that the #carotid body mediates peak #oxygen uptake during maximal physical exertion in rats 🫀 🏃 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Rémi Montané of toulouseuniversite.bsky.social et al. observes that brown #adipose tissue activity impacts systemic #lactate clearance in male mice 🔬 📉 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this study, Ysabella I. Ruiz-Pick et al. observed that KV channel antagonism blunts #vasodilatation in skeletal muscle of humans 🔎 🔬 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Jodie L. Koep et al. investigates preferential lactate #metabolism in the human brain during exogenous and endogenous #hyperlactataemia 🧠 🚴 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this #TopicalReview, Michael G. Jonz of uottawa.ca examines adaptations to #hypoxia in the vertebrate #retina 👁️ 🧠 🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Christoph T. Block et al. investigated saltatory #axonal conduction in the avian #retina 👁️ 🐦 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Rikard Frederiksen et al. examine the #evolution of rod bipolar cells and rod #vision in this #TopicalReview 🔬 👁️ 🔗 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Recent #Research by Espen Hartveit examined subcellular localization, kinetic properties and functional dynamics of #HCN channels in rod bipolar cells of rat #retina 🔎 👁️ 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this #TopicalReview, Victor Calbiague-Garcia of sorbonne-universite.fr et al. review current knowledge of #amacrine cells & discuss how emerging approaches are advancing our understanding of their function 👁️ 🐁 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this study, Thomas E. Zapadka et al. observed that #optic nerve injury impairs intrinsic mechanisms underlying electrical activity in a resilient #retinal ganglion cell 👁️ 🔬 📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this opening #Editorial, Jonathan B. Demb, Karin Dedek & Wei Li introduce the latest special issue 'Cellular and synaptic mechanisms of retinal processing' 📖 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Tian Kong & Lu-Yang Wang offer this #Perspective on dynamic inter-conversion between dendritic filopodia and spines based on the work of Liu et al. (2025) ✍️ 💭 🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Kristen M. Harris examines enhanced cycling of #presynaptic vesicles during long-term potentiation in rat #hippocampus in this recent #TopicalReview 📖 🔬 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

📣 Call for papers!!! 📣 Special Issue on New Approach Methodologies (NAMs) in Precision Medicine, fully open access with no author publication fees!

Recent #Research by Allison Spillane of uwhealth.bsky.social et al. investigates precision therapeutic #tRNA rescue of nonsense mutation R166X in KCNJ13 to restore K+ channel function 🧬 🔬 📜 Read it here: www.jprecisionmedicine.org/article/S305...

In this #TopicalReview, Yimei Cai & Tingting Wang discuss regulation of presynaptic homeostatic plasticity by glial signalling in #Alzheimer's disease 📖 ⚙️ 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Sofiia Reshetniak of uni-goettingen.de et al. examine the synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function in this #TopicalReview 📖 🧠 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

🎓 EDITOR'S CHOICE🎓 #Research by Nadine Dyszkant of unituebingen.bsky.social et al. observed that photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types 👁️ 🔬 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Hopefully of interest to scientists and exercise practitioners with and interest in muscle mass and functional gains in human volunteers. doi.org/10.1113/JP28... @jphysiol.bsky.social

In this #TopicalReview, Cristian A. Bogaciu & Silvio O. Rizzoli of uni-goettingen.de discuss membrane trafficking of synaptic adhesion molecules ✍️ 🔎 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Zsuzsanna Fekete et al. investigated #synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse #prefrontal cortex ⚙️ 🧠 📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

LATEST ISSUE LIVE⬇️ 'Cellular and synaptic mechanisms of retinal processing' 👁️🧠 🔗 physoc.onlinelibrary.wiley.com/toc/14697793...

Jeremy S. Dittman offers this #Perspective on the work of Lin et al. into vesicle priming states and the math of plasticity ✍️ 💭 🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Fabrice Abate of univ-amu.fr et al. offer this #Perspective on the findings of Furukawa et al. (2025) that cAMP reduces action potential amplitude and conduction velocity over long axonal distance 🧠 💭 🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Sandeep David et al. observed that Kif1a and intact microtubules maintain #synaptic-vesicle populations at ribbon synapses in zebrafish hair cells 🔬 ⚙️ 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

This study by Yaroslav E. Andrianov et al. finds that activation of TRPA1 and TRPM3 triggers Ca2+ waves in central terminals of sensory #neurons and facilitates #synaptic activity in the spinal dorsal horn ⚙️ 🧠 📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Julia Bandura & Zhong-Ping Feng of utoronto.ca offer this #Perspective on dynamin independent mechanism of exo-endocytosis coupling, based on the findings of Afuwape et al. (2025) ✍️ 💭 🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Svenja Bolz & Volker Haucke of fmp-berlin.de and freieuniversitaet.bsky.social examine #biogenesis and reformation of synaptic vesicles in this #TopicalReview 📖 🧠 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

This study by Hui-Jing Liu et al. examined activity-induced conversion from #dendritic filopodia to spines mediated by NMDA receptor-dependent calcium transients and vesicular #exocytosis 🔎 ↔️ 📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Audrey C. Drotos of umichnews.bsky.social et al. found that GluN2C/D-containing NMDA #receptors enhance #temporal summation and increase sound-evoked and spontaneous firing in the inferior colliculus 🔊 🧠 📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this opening #Editorial, Samuel M. Young Jr. and Lu-Yang Wang introduce "The giant impact of #synapses on brain function and disease" special issue 📖 📜 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Satya Murthy Tadinada of uiowacs.bsky.social et al. examined differential effects of #Phosphodiesterase 4A5 on cAMP-dependent forms of long-term potentiation in this recent study 💉 🧠 📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Chuangeng Zhang et al. observed that Kv4 channels improve the temporal processing of #auditory neurons in the #cochlear nucleus 👂 🧠 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this recent study, Ziyad W. Sultan et al. investigate control of #actionpotential afterdepolarizations in the inferior olive by inactivating A-type currents through #KV4 channels 🔎 📉 📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Kei Furukawa et al. investigates graded control of #Purkinje cell outputs by cAMP through opposing actions on axonal action potential and #transmitter release 🧠 🔬 📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

🎓 EDITOR'S CHOICE 🎓 This intriguing paper by Li et al. reveals the molecular bases by which the efficiency of transmission at the #neuromuscular junction is impaired in #aging mice. 📜 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...

Latest issue now live! 📖 This special issue examines the giant impact of synapses on brain function and disease and was organised and edited by Professor Samuel M. Young. 🧠 🔗 Access the full issue here: physoc.onlinelibrary.wiley.com/toc/14697793...

This study by Justine A. Lottermoser research-and-innovation.cornell.edu et al. investigates how #complexin gains effective access to the assembling SNAREs via its membrane-binding C-terminal domain 🔎 🧠 📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Cristina Román-Vendrell of mblscience.bsky.social et al. observed that acute introduction of monomeric or multimeric α-synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant #synapses 🧠 🧪 📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Thrilled to share Bella’s recent publication in @jphysiol.bsky.social! physoc.onlinelibrary.wiley.com/doi/10.1113/...

Yi-Mei Yang of utoronto.ca et al. observed that #intersectin-1 enhances calcium-dependent replenishment of the readily releasable pool of synaptic vesicles during development 🔬 ⚙️ 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Kun-Han Lin of mpi-nat.bsky.social et al. found that the number and relative abundance of #synaptic vesicles in functionally distinct priming states determine synaptic strength and short-term #plasticity ⚙️ 🧠 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this study, Olusoji A. T. Afuwape of ualittlerock.bsky.social et al. examined persistence of quantal #synaptic vesicle recycling in virtual absence of #dynamins ♻️ 🧠 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

In this recent #TopicalReview, Melissa Borgen & Brock Grill of seattlechildrens.org and uwdeptmedicine.bsky.social examine how ubiquitin ligase signalling networks shape #presynaptic development, function and disease 🚥 ✍️ 📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Manon M. M. Berns et al. observed that independently engaging protein tethers of different length enhance #synaptic vesicle trafficking to the #plasma membrane 🧠 🔎 📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Research by Yu-Tien Hsiao of ntu-taiwan.bsky.social et al. observes that deficiency of PKA-mediated SNAP-25b phosphorylation destabilizes exocytotic fusion pores and reduces the interactions of t-SNAREs ⚙️ 🔬 📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...