“Nothing is more rewarding than seeing new lab members arrive with curiosity and uncertainty, then develop the skills, confidence and independence to lead their own projects”, says @myofinlab.bsky.social Group Leader Marco Savarese in an interview for the Loimu Magazine: www.loimu.fi/verkkolehden...

Very happy news from our lab! 🎉 We are grateful to the University of Helsinki (@helsinki.fi ) for awarding a research-funded doctoral position starting in January 2026. Swethaa has been selected for this position within the Clinical Research Doctoral Program. 👏 (1/3)

🚨Publication alert!🚨 This project was a huge collaborative effort during Fanny’s first year of her PhD, and Jenni’s postdoc in @droch.bsky.social lab at the University of Copenhagen. (1/5)

Closing the year with gratitude and looking ahead to continued scientific progress. Happy Holidays from Myofin! 🌟

🚨Publication alert!🚨 First author Maria Francesca’s summary of the article: ”TTN is a huge and complex gene, and its rare variants are often hard to interpret.” (1/5)

End of the year celebrations with Myofin and FHRC 💃 @myofinlab.bsky.social @folkhalsanresearch.bsky.social

Can we just take a moment to appreciate this beautiful card my students made ❤️ There's images of fluorescent myosin! Wishing "Peaceful, and super-relaxed Christmas. May your ATP-storages be full, and muscle work efficient also next year" 😄💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social

Another art project at work 💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social

🚨Publication alert!🚨 First author Milla’s summary of the article: "In this study, we examined two families with dominantly inherited myopathy, presenting as exercise-intolerance, cramps and myalgia in the first family, and progressive muscle weakness in the second family.” (1/4)

🚨Publication alert!🚨 First author @jaakkosarparanta.bsky.social ’s summary of the article: (1/5)

Yesterday we hosted Lihastautiliitto and FSHD Finland, two patient advocacy groups in Finland, for a visit in the lab. Kiitos/thank you for coming! 💙 (1/3)

Check out Peter's discussion with Sarah Foye, President and Founder of Team Titin ! 💪 The interview was filmed as part of the 2025 Scientific and Family Conference hosted by Cure CMD, A Foundation Building Strength for Nemaline Myopathy and Team Titin.

🚨Publication alert!🚨 First author Veronica's summary of the article: "This study examined six individuals from five unrelated families who carried truncating variants in exon 363 of the TTN gene, all presenting with recessive titinopathies." (1/4)

🚨Publication alert!🚨 First author Johanna's summary of the article: "GNE myopathy is a rare autosomal recessive skeletal muscle disorder. It typically starts in the lower legs, gradually progressing to other muscle groups." (1/2)

🚨Publication alert!🚨 First author Veronica's summary of the article: "The study focused on finding a robust and reproducible method to differentiate the C2C12 murine myoblast into mature and functional myotubes in a 2D culture system." (1/3)

Meet our group members!🧬 ▫️Maria Francesca Di Feo (MD), Clinical Geneticist & Doctoral Researcher Maria Francesca (she/her) graduated in Medicine in 2020 from the University of Modena & Reggio Emilia and completed her specialization in Clinical Genetics at the University of Genova in 2025. (1/7)

Happy Halloween! 🎃👻🔮 The single muscle fibres won the ”Best Group Costume” prize at @folkhalsanresearch.bsky.social 🏆

Check out our recap videos from #EMC2025 and #WMS2025 on our Instagram 📹 : European Muscle Conference (www.instagram.com/reel/DPTJFxc...) World Muscle Society Congress (www.instagram.com/reel/DQOT_LV...)

🚨Publication alert!🚨 Marco’s summary of the article: ”New multicenter MRI study shows that in autosomal dominant titinopathies, Hereditary Myopathy with Early Respiratory Failure involves broad, severe fat replacement (esp. in semitendinosus, gluteus minimus and obturator externus), … (1/2)

Thank you @worldmusclesociety.org for an amazing meeting #WMS2025 💪🔬 The Finnish team thoroughly enjoyed the science and the networking! @myofinlab.bsky.social @folkhalsanresearch.bsky.social

A few highlights from a great week at #WMS2025 in #Vienna with the @myofinlab.bsky.social team!

Congrats to Maria Francesca and Johanna for their poster prizes! 🌟 #WMS2025 @worldmusclesociety.org

Great times with the Myofin team (@myofinlab.bsky.social) at #WMS2025 In Vienna !😂

@jaakkosarparanta.bsky.social presenting in the poster highlights session! 👏 #WMS2025 @worldmusclesociety.org

So many "MyoFinns" in the #WMS2025 meeting this year! 💪🔬 Representing @myofinlab.bsky.social @folkhalsanresearch.bsky.social

Our team is excited to connect - come find us at the @worldmusclesociety.org congress. 🇦🇹 Let’s talk science, collaboration, and future ideas! 🧬🤝💡 #WMS2025

During the week in between EMC and WMS, Jenni and Fanny visited the de Winter, Ottenheijm and Kirby labs at the Department of Physiology at Amsterdam UMC for an intro to single fibre mechanics and some interesting imaging techniques. 🇳🇱🔬 (1/2)

Starting my voyage towards Vienna and #WMS2025 on the Helsinki–Stockholm ferry.

Two years from today #Helsinki and #Finlandiahall will welcome #WMS2027, the annual congress of @worldmusclesociety.org. Save the date!

Greetings from the opening ceremony of the European Muscle Conference 2025! 🇳🇱 #EMC2025 #EuropeanMuscleConference

Our team is excited to connect - come find Jenni, Jaakko and Fanny at the European Muscle Conference. 🇳🇱 Let’s talk science, collaboration, and future ideas! 🧬🤝💡 #EMC2025 #EuropeanMuscleConference

Our team is excited to connect - come find Johanna at the Norwegian Conference for Hereditary Neuromuscular Disorders. 🇳🇴 Let’s talk science, collaboration, and future ideas! 🧬🤝💡

Registration for the @myofinlab.bsky.social - organized course, ILS144: "Genetic and genomic technologies in health care" is open. Link: tinyurl.com/43n2ydwu @folkhalsanresearch.bsky.social @helsinki.fi

When you get a feeling that someone's watching.. Our summer student making great progress with our AI analyses ❤️💪🔬 #muscleresearch #raredisease #myoblue @myofinlab.bsky.social @folkhalsanresearch.bsky.social

So many reasons to celebrate! And these guys are always up for some bubbles 🎉🥂💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social

Recent #Research by Jenni Laitila of folkhalsanresearch.bsky.social‬ et al. observes tha#pathogenicic TNNT1 variants are associated with aberrant thin filament compliance an#myofibrere hyper-contractility 🔬 🧬 🔗 Read the work here: https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP288109

Elina Engberg and Jenni Laitila are new Academy Research Fellows, and a joint project on the oral microbiome in health and disease received Academy Project Funding. @elinaengberg.bsky.social @laitilajenni.bsky.social @myofinlab.bsky.social @fin-hit.bsky.social research.folkhalsan.fi/news-article...

Meet our visiting researchers! 🧬🌍 ▫️Alessandra Carnazzi (MSc), Doctoral researcher Alessandra is originally from Italy. She pursued her master’s degree in medical biotechnology at the University of Milan. (1/5)

🚨Publication alert!🚨 First author Lydia’s and last author Vilma-Lotta’s summary of the article: "The majority of known structural variants (SVs) of the nebulin gene (NEB), such as intragenic duplications, deletions, and copy number variants of the triplicate region, cause..." (1/4) #MyoBlue

We are very grateful to the Research Council of Finland (Suomen Akatemia) for funding our research on neuromuscular disorders. Thank you / Kiitos / Tack! 💙 Jenni has been awarded an Academy Research Fellowship, which entails a 4-year grant. Jenni shares what the grant will be used for 👇: (1/4)

Go team go! ⚽️🙌🏻 @folkhalsanresearch.bsky.social

Meet our visiting researchers! 🧬🌍 ▫️Giuliana Capece (MD), Neurologist & Doctoral researcher During her Neurology Residency at the University of Padua, Giuliana developed a strong interest for neuromuscular diseases. (1/5)

Cleaning day at @folkhalsanresearch.bsky.social completed! 🧼🧑‍🔬

Welcome our new @eshgyoung.bsky.social Committee Members! 🧬 4 new members will be joining the ESHG-Young Committee this year! Maria Francesca di Feo (Italy/Finland) Nelson Martins @nelsonm1224.bsky.social (Belgium) Mathys Weber (France) Ewelina Bukowska-Olech (Poland) #ESHG2025 @eshg.bsky.social

Yesterday we had the first (but not last) Myofin Young Investigators Day! 🌟 The day was filled with great presentations from our young researchers and out-of-the-box questions from the audience. Thank you to Jenni, Veronica and Marco for organizing the event! 💙

🚨Publication alert!🚨 doi.org/10.1177/2214... First author Milla’s summary of the article: ”The objective of this study was to identify and further investigate the causative genetic variant in a patient with lethal nemaline myopathy.” (1/6) #MyoBlue

Our team is excited to connect – come find us at #ESHG2025, or reach out to set up a meeting. Let’s talk science, collaboration, and future ideas! @eshg.bsky.social #ESHG #Networking #ResearchCollaboration #Myofin

🧬 Meet our group members! 🧬 ▫️Milla Laarne (MSc), Doctoral researcher Milla graduated with a master’s degree in Genetics and Molecular Biosciences from the University of Helsinki in June 2022. (1/5)

🎉 We are thrilled to announce that Myofin researcher Maria Francesca Di Feo has been elected as a member of the ESHG Young Board (European Society of Human Genetics, @eshg.bsky.social)! (1/3)

Our study highlights how understanding differential exon usage can improve the diagnosis and prognosis of titin-related diseases. This could be applied to other genetic disorders, as 70% of the human genes show variable exon usage. @myofinlab.bsky.social research.folkhalsan.fi/annual-repor...