Renewing my yearly bet on Cooper/Miller for the Nobels. One might think that I would learn after being wrong so many times, but one would be mistaken. laskerfoundation.org/winners/b-an...

This is very serious! Our job as scientists is to protect the truth we know it based on evidence. Whistle blower protection is so fundamental to achieving that. While pubmed is "down", I'm wondering if papers on vaccines are magically disappearing. Jeanne Marrazzo is a national treasure!

Virally encoded interleukin-6 (vIL-6) coordinates with human IL-6 to modulate cytokine expression during KSHV infection https://www.biorxiv.org/content/10.1101/2025.10.02.679950v1

Great job @sarasuliman.bsky.social on discussing the evolution of Mycobacterium tuberculosis in human populations over time #TBSky #IDSky #MedSky 🧪 #genetics www.nature.com/articles/s41...

Jane Goodall, ethologist and conservationist, has died. She was 91

This moment from our latest episode with science writer @edyong209.bsky.social is 🔥 We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪 Listen wherever, or watch on Spotify 👇 open.spotify.com/episode/7Evh...

US judge rejects bid by Sean 'Diddy' Combs to overturn prostitution conviction reut.rs/3IE83C8

Kaiwen Zhu, Yan Lu, André Veillette et al. @ircm.bsky.social show that CD2 & its ligands regulate #MAITcell development and antigen responses by enhancing TCR signaling. A natural subset of human MAIT cells lacking CD2 exhibits reduced activation responses to antigen. rupress.org/jem/article/...

Good title this: "Tuberculosis and the perils of historical amnesia" Good reminder about "...the enduring role of poverty, overcrowding, and substandard housing in sustaining tuberculosis in the present era.." #TBSky #IDSky @lancetmicrobe.bsky.social

Type I IFN drives #neutrophil swarming, impeding lung T cell–#macrophage interactions and #TB control, say William Branchett, Anne O’Garra et al. @crick.ac.uk rupress.org/jem/article/... #Tuberculosis

New study shows pyrazinamide kills TB by acidifying bacterial cytosol — not via PanD/CoA depletion. A long-standing debate settled, paving the way for smarter PZA-like drugs. #MicroSky ✍️ J. Laudouze, Y. Antonenko, @alexandregouzy.bsky.social, @pierresantucci.bsky.social & coll. 📖 shorturl.at/tuz6Q

Timeline cleanse 🎻❤️

Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections @natimmunol.nature.com www.nature.com/articles/s41...

Monday, what's up?

Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org! It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance. Huge congrats to Wendy & colleagues! shorturl.at/WbFQC

"Checks and balances"

"The group brings together hundreds of grandparents nationwide who lived through diseases such as polio, tuberculosis and measles — illnesses once thought eliminated in the United States..." www.kgw.com/article/news...

HSPCs as reservoirs for trained immunity elifesciences.org/articles/106...

We need more kindness in this world.

The number of Americans receiving unemployment benefits for at least a week rose to the highest level since late 2021, according to Labor Department data.

Penguin’s reaction when her favorite human comes to check up on her... 🥹 #bluesky

🧪 Senate appropriators say: NIH's budget gets a... boost! Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%). "Congress has your back," said @murray.senate.gov. ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.

Delighted to see this story out and collaborate with amazing teams led by @jdegregori.bsky.social Mercedes Rincon & @roelvermeulen.bsky.social. Proud to see science propelled by our lab @cdi-einstein.bsky.social expanded to better understand cancer dormancy. Congrats! www.nature.com/articles/s41...

NIH wants to hear from you. No really. Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs grants.nih.gov/grants/guide...

Happy to share the most recent preprint from the lab, the thesis work of Dr. Adam Krebs and a collaboration with many, including the Geissmann lab @mskcancercenter.bsky.social Here is a short paper thread. #tuberculosis #macrophages 🦠 www.biorxiv.org/content/10.1...

The NIH was healthiest when pay lines were in the 20th percentile range. We are headed into an environment where pay lines are in the 5% range. In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one. This is going to destroy science.

"On the one hand, we have a hypothesis underpinned by evidence, although imperfect, and on the other hand we have a hypothesis without evidence, although it might exist." Our latest editorial in advance of our August issue www.thelancet.com/journals/lan... #IDSky #ClinMicro #ViroSky #SARS-CoV-2

So sad, malaria increasing up to 10 fold in Southern Africa due to climate change - africacdc.org/news-item/ma...

This entire series of statements from Federal employees speaking out against Doge cuts is remarkable. Definitely worth a listen. Each statement is short and powerful, and the creators of the series did well to platform folks across multiple agencies. Our Federal workers are among the best of us.

Talk about The Wire, Sopranos, Game of Thrones all you want, but the greatest US television program ever made is Sesame Street. It's not even close. 50+ years of treating kids across class, ethnicity, religion not as mini-consumers...but as citizens with a stake in this world.

Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu

One NIH diversity supplement grant reinstated! we'll take the win! now if we can just get our delayed NOA on the parent grant to come through...

Are you interested in #immunometabolism but not sure where to start? Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now. shop.elsevier.com/books/metabo... (1/n)

Genetic control of the transcriptional response to active tuberculosis disease and treatment https://www.biorxiv.org/content/10.1101/2025.04.11.648383v1

I’m all for more NAMS, but it has its limits. There are no LLMs or organs-on-a-chip that can model viral pathogenesis, vaccine efficacy, or candidate drugs. We only use animals when there is no other choice. This will only stop more lifesaving research. www.drugdiscoverytrends.com/nih-announce...

Experts estimate USAID cuts are leading to 88 deaths PER HOUR. A UN office called these “the deepest funding cuts ever to hit the international humanitarian sector.” If funding isn't resumed, they estimate an additional 10 million cases & 2 million preventable deaths by 2030: tb.impactcounter.com

The National Institutes of Health announced on Monday that the biomedical agency would no longer award funding to new grant proposals solely relying on animal testing www.drugdiscoverytrends.com/nih-announce... #nih #research #science #pharmacology

As of July 6, the United States reported 1,281 measles cases in 2025, the highest total since the disease was declared eliminated in 2000. 1/5

BREAKING: Six leading medical organizations filed a lawsuit on Monday against Robert F. Kennedy Jr., the health secretary, and the health dept, charging that recent decisions limiting access to vaccines were unscientific and harmful to the public. (Gift link) www.nytimes.com/2025/07/07/h...

New story up on STAT this morning... www.statnews.com/2025/07/06/h... 1/n

Summary Table of the massive defunding of biomedical research in the United States www.nytimes.com/interactive/...

I keep thinking about @kamalaharris.com and all the extremely highly qualified women of color who are held to ridiculously higher standards than their peers.

The average age of empires is 250 years. We're right on schedule with #OBBBA.

PLEASE SHARE WIDELY (IN *ALL* PLACES)!!! Don't know if Medicaid cuts affect you? Check out this graphic by PA Chapter & Copello Fellow @drsforamerica.bsky.social Dr. Robiou made. Yup-you followed it correctly: these cuts affect EVERYONE. Pass it on.

Shameful and inhumane. #OBBBA

This really is a looming crises. OBBBA Would Accelerate Social Security & Medicare Insolvency-2025-06-27 share.google/iWIjJwxA07kl...