Lab’s 1st preprint! Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate. @cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation. He is on the job market!

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵

Join us on November 4th! The winners of our best short talk awards will be telling their research on the @isscr.org stage! Thank you @stemcellreports.bsky.social for co-organizing this webinar!

This is it. The act of science -like art- is not the output, it is the interaction and the process. What makes us the kind of scientists we are is how we approach the problem 🧪

Final version @science.org "Recent evolution of the developing human intestine affects metabolic and barrier functions". Evolutionary preparation for microbiota, diet, and pathogen exposure is fascinating! Thank you @erc.europa.eu for supporting our vision! www.science.org/doi/10.1126/...

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

Altogether, we identify the developing human intestinal epithelium as a rapidly evolving system, and show that great ape #organoids provide insight into human biology. 🙏Thanks 🙏 to all authors! Especially co-first authors: @CY_Qianhui_YU @KlkUmut @stefanosecchia 11/11

Diet/microbes place the gut epithelium as a nexus for evolutionary change. With Jason Spence and Craig Lowe labs we use #organoids to explore how evolution prepared the developing human intestine for exposure to the environment. @science.org #evodevo www.science.org/doi/10.1126/... 1/11

🚨 After 7 years in the making, my PhD thesis work is finally published in @science.org 🧬✨ What does our gut say about how we became human? During my hitchhiking journey spanning 3 countries and multiple lab moves

My postdoc work at Treutlein lab and @graycamplab.bsky.social with @jasperjanssens.bsky.social is out in @science.org ! We screen for neuron subtypes using pro-neural TFs + morphogen combinations + scRNA-seq and profiled over 700,000 cells in 480 conditions. www.science.org/doi/10.1126/...

Our study on a male-essential microRNA and the evolution of other dosage compensation mechanisms in birds is now out in Nature! www.nature.com/articles/s41...

Elegant and insightful study on gut evolution and development - congratulations 🎊@graycamplab.bsky.social @umut-kilik.bsky.social www.science.org/doi/10.1126/...

Recent evolution of the developing human intestine affects metabolic and barrier functions @science.org @graycamplab.bsky.social www.science.org/doi/10.1126/...

An organoid model of the menstrual cycle reveals the role of the luminal epithelium in regeneration of the human endometrium https://www.biorxiv.org/content/10.1101/2025.07.03.663000v1

Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social‬ @jasperjanssens.bsky.social‬ and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1

✨Exciting news!✨ The World Endometriosis Research Foundation (#WERF) – Endometriosis Phenome and Biobanking Harmonisation Project (#EPHect) today publishes #SOPs to optimize the use of experimental in vivo and in vitro models in #endometriosis research.

Katie Kubek from @novartis.bsky.social showed the work they have been doing with dog intestinal organoids 🐶 Exciting insights into serotonin signalling in mammals!

🤩We had a fantastic time at #BaCell3D in Basel (June 23–25)! 🧬It was great to #exchange ideas on 3D cell culture, #organoids & in-vitro systems. 🤝Thanks to our Swiss #partner Vitaris AG – for joining us!🇨🇭 👋See you at the next #BaCell3D! #organoids #BaCell3D #networking

Highlights from our day1 conference dinner and networking event at the local favorite multi-cuisine bar and restaurant-Klara. Nerdy N2 B27 shots to welcome everyone , table soccer tournament, music and lots of discussions !

Incredibly impressed by the student/postdoc run @bacell3d.bsky.social conference. Great talks, a vibrant community, and so well organised 👏

@sbwil91.bsky.social is our next speaker from Melissa Little’s group at the reNEW @novonordisk.bsky.social telling us about his work on multi lineage kidney assembloids

Beautiful selected talk by Hao-An Hsiung from EPFL showing us human trunk assembloids with remarkable cell diversity, notochord and the gut tube!

@maxmmahe.bsky.social Human intestinal organoids mature much faster when transplanted in vivo. Surprising discoveries on tubular organoids demonstrating higher cellular complexity!

Amazing presentation by @mendjanlab.bsky.social explaining the potential of human cardioids. Increasing complexity step by step to generate more in vivo-like organoids!

A selected talk from @clarissebrunet.bsky.social investigating gliogenesis in brain organoids 🧠

We are very excited to close this years meeting with a keynote talk by Prof Jason Spence from @umich.edu. Understanding human lung development with bud tip, airway and Alveolar type2 (AT2)organoids. Unexpected transcriptional heterogeneity found in early postnatal AT2 cells occupying distinct niches

And it’s ongoing , in development, evolving!

We are very happy to have Reiner Wimmer with us talking about his work done at Pathology and applied safety sciences (PaSS) at Roche pRED. Check out his work on developing vascular organoid models for investigative toxicology

Selected talk by Amanzhol Kurmashev about “3D human urothelial model for real-time analysis of bacterial infection dynamics and therapeutic interventions" @ethz.ch @eth-bsse.bsky.social @nccr-antiresist.bsky.social

A project initiated during a pandemic! Samy Gobaa told us about their bioengineering approaches on modeling infections in human lung-on-chip 🫁

A great talk by @adrianranga.bsky.social on in vitro neural tube morphogenesis! Interesting findings on the role of calcium waves preceding tissue movements!

The supremely successful panel discussion from last years @bacell3d.bsky.social is back! What do you wanna ask??

Takanori Takebe joined from the U.S. to share his latest research on multi-zonal liver organoids, including new findings on generating liver bud organoids that incorporate sinusoidal vessels!

Our 3rd new PI highlight talk is by Prof David Bruckner @davidbrueckner.bsky.social who just started his group in theoretical physics of living systems @biozentrum.unibas.ch on “Information flow in self-organized developmental system

Elisa Magistrati presented her work on modeling trophoblast invasion in vitro

Day 2! We begin with the disease modeling and drug discovery session with Francis Jacob @unibas.ch talking about multimodal profiling and drug treatment prediction in ovarian cancer

Sarah Pallet PhD student from @uniheidelberg.bsky.social hospital, giving a selected talk on “Human intestinal organoids to study the stem cell niche as a potential reservoir for hepatitis E virus infections”. Sarah is 1 of 11 who got our new Science bridging program fellowship to attend this year!

New PI highlight talk! By @hsiuchuanlin.bsky.social who just started her group @crg.eu Barcelona. “Profiling and programming in vitro neuronal diversity at single-cell resolution”

We are very excited to hear Lauriane Cabon from IHB, Roche, CH presenting “Next-Generation Drug Discovery: Harnessing the Power of Advanced Multicellular Systems

Very excited to have Prof. Chris Tape (University College London, UK) “Single-cell Phenoscaping of Tumour Microenvironment Organoids @christophertape.bsky.social What makes the phenotype of a cell?

Wonderful to be back at @bacell3d.bsky.social and so awesome to combine science with a tad of art (I can’t believe this is 100% by hand!)

@bacell3d.bsky.social 2025 has begun with a bang! Time for a start selfie!

Our first talk @bacell3d.bsky.social is by Delilah Hendricks who co-leads her group with Benedetta Artigiani at the Princess Maxima Centre, NL. She presents her work on developing human brain organoid models for studying development and cancer.

Excited to be in Basel for BaCell3D @bacell3d.bsky.social

Next up @bacell3d.bsky.social is De. Vikas Trivedi ( @viktri08.bsky.social) from @embl.org Barcelona, talking to us about self organization and constraints in biological systems especially during axis formation . Crosstalks, metabolism and networks!

Micropatterned gastrointestinal organoids and stomach organoids to study host pathogen infections! by Moritz Hofer from EPFL @bacell3d.bsky.social

@canaztekin.bsky.social @bacell3d.bsky.social presents his work on oxygen sensitivity and the evolution of limb regeneration ! Air liquid interphase cultures to study regeneration in vitro

We are very excited to have our first keynote talk by Prof. Agnete Kirkeby @kirkebylab.bsky.social @bacell3d.bsky.social ! Agnete’s work is foundational in understanding human neurodevelopment using hES cells and bridging fundamental research with therapies and clinical trials for Parkinson’s

We’re all set! With 400 participants, 200 posters, and a stellar scientific program featuring both renowned experts and emerging researchers, BaCell3D 2025 is shaping up to be another unforgettable event—happening June 23–25 at the ZLF Hall, University of Basel.

Getting ready for @bacell3d.bsky.social next week!