“Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans” New work on HAQERs, by @rimangan.bsky.social Yanting Luo Craig Lowe @debbysilver.bsky.social @manoliskellis.bsky.social & colleagues 🧪🧬 www.biorxiv.org/content/10.1...

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

Taking a snippet of genetic code that is unique to humans and inserting it into mice helps them grow bigger brains than usual https://go.nature.com/3GOTQkz

Amazing work from the Silver Lab! Grateful to have been part of such meaningful story!

Happy to see my PhD work in the Fleischmann lab at Brown University @carneyinstitute.bsky.social published in @natureneuro.bsky.social! -Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution nature.com/articles/s41...

Happy to share some good news today, and our latest study on DDX3X! Led by super talented @federicamosti.bsky.social we use live imaging, transcriptomics and interaction studies to define how clinically diverse missense mutations in DDX3X influence neural development. dx.plos.org/10.1371/jour...