✨Exciting news✨ #MHR is proud to announce a new peer-reviewed article format to showcase groundbreaking research in a short report format: the ‘Concise Communication’! More information at the link below 🔗📚 academic.oup.com/molehr/artic...

#Fertilization is a complex, multi-step process involving interaction of the sperm with the oocyte. The #sperm need to navigate to the #reproductivetract evading the female immune system to successfully fertilize the oocyte.

“Prophylactic treatment with #progesterone decreases murine #miscarriage by suppressing the immunostimulatory activity of #macrophages” 🔗📚 academic.oup.com/molehr/advan...

Recent research investigated if there were #sexdifferences in the response of the #placental transcriptome to #maternal #foodrestriction, and found that while there were few interactions between sex and food restriction, the sex-stratified analyses yielded several of ‘sex-specific’ effects

@MHR_ReprodSci Associate Editors attended the Upper Midwest Summit for Reproductive Science, representing our journal! Great science and networking opportunity! 🤩 Nardhy Gomez-Lopez Sara Pietroforte Farners Amargant Riera Francesca Duncan WashU Medicine OBGYN Northwestern Medicine

Do you know that maternal diet-induced obesity (DIO) may affect adult offspring #oocytequality due to #mitochondrial dysfunction?

📣”#BitterTaste signaling pathway is required for #spermatogenesis and maintenance of male #fertility in mice” 📚🔗Don’t miss this interesting article! academic.oup.com/molehr/artic...

Heads up, #ReprodSci community! Interested in the impact of #MaternalAge on #OocyteQuality? Do not miss the latest #EditorChoice article, where the authors explored the transcriptome signature of age-related decline in oocyte quality. 📚🔗👇 academic.oup.com/molehr/artic...

Dive into this fascinating #review on #spermatogonial stem cell and fibroblast growth factor #signaling recently published in #MHR! 📚🔗👇 academic.oup.com/molehr/artic...

📣“ACTRT2 deficiency increases #spermatogonia vulnerability to #ferroptosis” 📚🔗Have a look at the article 👇 academic.oup.com/molehr/advan...

📣”#Fertility is compromised after oocyte-specific #deletion of microtubule severing protein #KataninA1” #oocytecompetence #meiosis #microtubules #spindle 📚🔗Dive into the full article 👇 academic.oup.com/molehr/artic...

✨Are you an early career scientist within 10 years of an independent position? Submit your innovative #research in #MHR Early Career Innovator Series by the end of September and #compete for the 2025 Early Career Innovator Award!! academic.oup.com/molehr/pages...

Just back from vacation 🏖️ and looking for a great read? Dive into #MHR latest article in the Early Career Innovator Series on #fetal reproductive organ #development. academic.oup.com/molehr/pages...

In vitro follicle culture is an emerging #FertilityPreservation solution for women and children with cancer. Recent advances have yielded various 3D methods that preserve follicular structure. Which is the best?🧐

“Early signaling pathways during in vitro culture of isolated primordial follicles” Don’t miss this interesting piece investigating the main transcriptional events and molecular factors determining follicle fate 🧫🐮 Dive into the full article 🔗👇 academic.oup.com/molehr/artic...

🚨Save the date for the Symposium on the Paternal Origins of Health and Disease! 🗓️October 16th, 2025 📍Institut Cochin (Paris, France) and online 🔗 Registration👇👇

✨Exciting news!✨ The World Endometriosis Research Foundation (#WERF) – Endometriosis Phenome and Biobanking Harmonisation Project (#EPHect) today publishes #SOPs to optimize the use of experimental in vivo and in vitro models in #endometriosis research.

🤩 See you soon at the #MHRsymposium!! 📍 Session 53, Tuesday from 14:00-15:15 Oxford University Press @eshre.bsky.social

🤩ESHRE journals’ “Parisian cafe'” at #ESHRE2025!! Oxford University Press European Society of Human Reproduction and Embryology (ESHRE) @eshre.bsky.social #MHR #ESHREjournals #EarlyCareerInnovatorSeries

Excited for #ESHRE2025 in Paris!!🤩 Join us at the Precongress Course 12: “Academic authorship - Milestones in reproductive science: highlights from ESHRE Journals”

📣Now online! “Eutopic #macrophages facilitate #endometriosis progression via ferroptosis-mediated release of S100A9” academic.oup.com/molehr/advan...

Uterine #leiomyomas, also known as #fibroids, are benign tumors found in about 60% of pre-menopausal women, and can cause abnormal uterine bleeding, pelvic pain and #infertility.

📣New paper alert on #human sperm protamine proteoforms! Using a refined top-down mass spectrometry protocol, the authors observed significant differences in specific #ProtamineProteoforms related to sperm #chromatin packaging #alterations, #obesity and #aging.

✨The #ESHRE Annual Meeting 2025 is just around the corner! Join us at the #MHRsymposium where MHR’s Editor-in-Chief, @Boiani Michele, and Deputy Editor, @Francesca Duncan, will be hosting the session about Basic principles of ovarian function in vivo and in vitro.

“#Mechanical signal-mediated mitochondria–endoplasmic reticulum contacts modulate Leydig cell testosterone biosynthesis during #testisdevelopment” Free to read 🔗📚 academic.oup.com/molehr/artic...

#Mosaicism is generally defined as heterogeneity of DNA content among the #embryonic cells. Using a novel method enabling simultaneous sequencing of both gDNA and mRNA, this study elucidates the transcriptomic profile of #MosaicEmbryos.

#2024 MHR Early Career Innovator Award winner Dr Olga Astapova! www.linkedin.com/posts/europe...

✨MHR is proud to announce the winner of the #2024 MHR Early Career Innovator Award! Congrats to Dr. Olga Astapova for her study “Paxillin regulates androgen receptor expression associated with granulosa cell focal adhesions” 🥇 academic.oup.com/molehr/artic...

📣📣Calling all early career scientists!! Don’t miss the opportunity to showcase your original research in MHR’s #EarlyCareerInnovatorSeries and join the race for the prestigious #2025 Award! 🥇 Learn more here 👇 academic.oup.com/molehr/pages...

Don’t miss this interesting article on #placental DNA methylation. “Profiling (placental) #DNAmethylation in cell-free DNA across #gestation: the Rotterdam Periconception Cohort” Free to read 🔗📚 academic.oup.com/molehr/artic...

In primates and rodents, the establishment and maintenance of #pregnancy require appropriate development of specialized maternal tissue, the #decidua. Decidual cells arise from uterine stroma, form close relationships with placental structures and facilitate embryo development.

📣New article! “Single-cell metabolomics reveals that #bisphosphoglyceratemutase influences #oocyte maturation through glucose metabolism” 🔗📚 academic.oup.com/molehr/artic...

New article #spotlight about the mechanisms underlying sex differences in the response to, and long-term effects of, early-life environmental exposure.

Just 4 weeks to go until #ESHRE2025!! 👇 www.linkedin.com/posts/europe...

Another fascinating study on #Endometriosis is available in #MHR! academic.oup.com/molehr/artic...

#Endometriosis is an inflammatory condition characterized by the abnormal growth of endometrial tissue outside the uterus, affecting about 10% of women of reproductive age. This condition can severely impair #reproductivehealth and contribute to #infertility.

Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor Chih-Jen (Lance) Lin #MHR #reproduction #epigenetics #oocytetoembryotransition #femaleinfertility European Society of Human Reproduction and Embryology (ESHRE) Oxford University Press The University of Edinburgh

#First successful generation of naïve marmoset ES cells and blastoids is now in the #MHR Early Career Innovator Series! The authors explored the #marmoset as a non-human #primate model for studying chromosomal instability and #aneuploidy during early #embryo development.

📣 Check it out: “#human platelet-rich plasma promotes #primordial follicle #activation via the PI3K/Akt signaling pathway” 🔗📚👇 academic.oup.com/molehr/artic...

📣Don’t miss the opportunity to dive into this fascinating #review on #ProteinTargeting reverse genetic approaches, like Trim-Away and auxin-inducible protein degradation, and their applications in #oocyte and #embryo research! 🔗📚👇 academic.oup.com/molehr/artic...

📣Another interesting read in the #MHR latest issue! In this study, the authors explored the #bioenergetics of #human spermatozoa in patients with testicular germ cell #tumour. 🔗📚👇 academic.oup.com/molehr/artic...

#MMAF (Multiple morphological abnormalities of the flagellum) syndrome is a complex genetic disorder resulting in complete infertility in affected patients. In addition to multiple flagella defects, spermatozoa from MMAF patients present various types of head defects.

📣Check out the latest article in the #MHR Early Career Innovator Series on #MeioticRecombinationFailure and #NonObstructiveAzoospermia. #EarlyCareerInnovatorSeries

✨Do you know that the #2025 MHR Early Career Innovator Award is now open? 🤩 If you are an #EarlyCareer scientist, do not miss the opportunity to showcase your innovative #research in the #MHR Early Career Innovator Series and #compete for the 2025 Award! 🥇 academic.oup.com/molehr/pages...

Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor Marcos Chiaratti #MHR #meetthescientist #reproduction #mitochondria #oocytequality #fertility @ESHRE Oxford University Press Universidade Federal de São Carlos - UFSCar Oficial

📣 New article in #MHR! “MCP-1 promotes ILK phosphorylation at Ser246 during #endometriosis development and affects the #pregnancy outcome” 🔗📚👇 academic.oup.com/molehr/advan... @ESHRE Oxford University Press

Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor Lisa Mehlmann #MHR #reproduction #meetthescientist #ovarianbiology #folliclegrowth #oocytematuration #oocytequality @ESHRE Oxford University Press University of Connecticut

📣 During #spermiogenesis, #chromatin in germ cells undergoes significant condensation, with most #histones being replaced by a species-specific ratio of Protamin1 and Protamin2. Altered PRM1/PRM2 ratios are associated with #subfertility and #infertility.

Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor Martin Gauster #MHR #meetthescientist #trophoblast #development #placenta @ESHRE Oxford University Press @UniGraz

Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor Jacek Malejczyk #MHR #meetthescientist #reproduction #immunology #endometriosis @eshre.bsky.social @OPU @UniWarszawski