Publish your original research in MHR’s Early Career Innovator Series and compete for the MHR Award! 🏆 The winner gets an all-expenses-paid trip to present at the next ESHRE Annual Meeting. Read the criteria and submit: academic.oup.com/molehr/pages...

🔬 New in MHR! Could the liver protein ORM2 hold the key to new #PCOS treatments? Xu et al. show that while Orm2 KO worsens ovarian pathology, recombinant ORM2 supplementation improves ovarian morphology & Ucp1 expression! 💡 📖 Read the full study: academic.oup.com/molehr/artic... #MHRJournal #ESHRE

🔬 Is the embryo's "blueprint" set before the first division? New research in @MolHumReprod by Thomas Nolte & Michele Boiani’s team shows the oocyte isn't a blank slate. Sperm entry site & ooplasm distribution dictate the fate of the first blastomeres. 🧬 🔓 Open Access: lnkd.in/eGVs6_BM

We love seeing complex biology beautifully mapped out! 🧬✨ If you are interested in reproductive medicine, you need to check out our latest Editor's Choice! Professor Fauser reviews the incredible journey of AMH. It’s fully OA, so dive right in with your morning coffee: doi.org/10.1093/mole...

🌟 EDITOR'S CHOICE 🌟 How does maternal obesity impact placental vascular development? 🤔 A new review by Ramanlal, James & Boss ( @AucklandUni ) explores how inflammation disrupts angiogenesis & alters fetal growth. 📖 Read: pubmed.ncbi.nlm.nih.gov/41530408/#Pl... #MaternalObesity

Wrapping up a manuscript in reproductive or developmental biology? (And yes, we welcome research across ALL mammalian species, not just human!) 🔬🧬 Why submit to Molecular Human Reproduction (MHR)? Read all 10 reasons here: academic.oup.com/molehr/pages... #ReproBio #DevBio #AcademicPublishing

Are you interested in understanding more about #preeclampsia? Do not miss out the latest #review published in #MHR discussing limitation and challenges of studying this #pregnancy-specific syndrome. 🔗📚 academic.oup.com/molehr/artic...

“Fertilization failure #assay identifies stage-specific arrests in couples with #total fertilization #failure” 🔗📚 academic.oup.com/molehr/artic...

✨Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor for Scientific Visualization @Jeff Pea #MHR #meetthescientist #reproduction @eshre.bsky.social @medillschool.bsky.social

“Temporal dynamics of #uterine #immune microenvironment remodeling in a murine model of #adenomyosis” 🔗📚 academic.oup.com/molehr/artic...

London calling! #ESHRE2026 registration OPEN! What's in store: • Precongress courses • 80+ sessions • Networking & new science • Topics: genomics, AI, ART, immunology, policy & more 📍ExCeL London | 5-8 July 26 ⏰ Abstract deadline: 2 Feb 2026 🔗 www.eshre.eu/ESHRE2026/Re...#ESHRE2026#HumanReproduction

Ovarian #fibrosis is an emerging factor contributing to ovarian dysfunction, #aging, and female #infertility. Several molecular mechanisms have been investigated to identify the key molecular #pathways driving ovarian fibrosis, including TGF-b/Smad, Wnt/b-catenin and PI3K/Akt pathways.

✨Hello 2026! ✨ We are starting the new year with fresh ideas, exciting groundbreaking articles, new connections, and big initiatives! Stay tuned! 📣 #MHR #reproduction @eshre.bsky.social academic.oup.com/molehr

✨Exciting news✨ #MHR is proud to announce a new peer-reviewed article format to showcase groundbreaking research in a short report format: the ‘Concise Communication’! More information at the link below 🔗📚 academic.oup.com/molehr/artic...

#Fertilization is a complex, multi-step process involving interaction of the sperm with the oocyte. The #sperm need to navigate to the #reproductivetract evading the female immune system to successfully fertilize the oocyte.

“Prophylactic treatment with #progesterone decreases murine #miscarriage by suppressing the immunostimulatory activity of #macrophages” 🔗📚 academic.oup.com/molehr/advan...

Recent research investigated if there were #sexdifferences in the response of the #placental transcriptome to #maternal #foodrestriction, and found that while there were few interactions between sex and food restriction, the sex-stratified analyses yielded several of ‘sex-specific’ effects

@MHR_ReprodSci Associate Editors attended the Upper Midwest Summit for Reproductive Science, representing our journal! Great science and networking opportunity! 🤩 Nardhy Gomez-Lopez Sara Pietroforte Farners Amargant Riera Francesca Duncan WashU Medicine OBGYN Northwestern Medicine

Do you know that maternal diet-induced obesity (DIO) may affect adult offspring #oocytequality due to #mitochondrial dysfunction?

📣”#BitterTaste signaling pathway is required for #spermatogenesis and maintenance of male #fertility in mice” 📚🔗Don’t miss this interesting article! academic.oup.com/molehr/artic...

Heads up, #ReprodSci community! Interested in the impact of #MaternalAge on #OocyteQuality? Do not miss the latest #EditorChoice article, where the authors explored the transcriptome signature of age-related decline in oocyte quality. 📚🔗👇 academic.oup.com/molehr/artic...

Dive into this fascinating #review on #spermatogonial stem cell and fibroblast growth factor #signaling recently published in #MHR! 📚🔗👇 academic.oup.com/molehr/artic...

📣“ACTRT2 deficiency increases #spermatogonia vulnerability to #ferroptosis” 📚🔗Have a look at the article 👇 academic.oup.com/molehr/advan...

📣”#Fertility is compromised after oocyte-specific #deletion of microtubule severing protein #KataninA1” #oocytecompetence #meiosis #microtubules #spindle 📚🔗Dive into the full article 👇 academic.oup.com/molehr/artic...

✨Are you an early career scientist within 10 years of an independent position? Submit your innovative #research in #MHR Early Career Innovator Series by the end of September and #compete for the 2025 Early Career Innovator Award!! academic.oup.com/molehr/pages...

Just back from vacation 🏖️ and looking for a great read? Dive into #MHR latest article in the Early Career Innovator Series on #fetal reproductive organ #development. academic.oup.com/molehr/pages...

In vitro follicle culture is an emerging #FertilityPreservation solution for women and children with cancer. Recent advances have yielded various 3D methods that preserve follicular structure. Which is the best?🧐

“Early signaling pathways during in vitro culture of isolated primordial follicles” Don’t miss this interesting piece investigating the main transcriptional events and molecular factors determining follicle fate 🧫🐮 Dive into the full article 🔗👇 academic.oup.com/molehr/artic...

🚨Save the date for the Symposium on the Paternal Origins of Health and Disease! 🗓️October 16th, 2025 📍Institut Cochin (Paris, France) and online 🔗 Registration👇👇

✨Exciting news!✨ The World Endometriosis Research Foundation (#WERF) – Endometriosis Phenome and Biobanking Harmonisation Project (#EPHect) today publishes #SOPs to optimize the use of experimental in vivo and in vitro models in #endometriosis research.

🤩 See you soon at the #MHRsymposium!! 📍 Session 53, Tuesday from 14:00-15:15 Oxford University Press @eshre.bsky.social

🤩ESHRE journals’ “Parisian cafe'” at #ESHRE2025!! Oxford University Press European Society of Human Reproduction and Embryology (ESHRE) @eshre.bsky.social #MHR #ESHREjournals #EarlyCareerInnovatorSeries

Excited for #ESHRE2025 in Paris!!🤩 Join us at the Precongress Course 12: “Academic authorship - Milestones in reproductive science: highlights from ESHRE Journals”

📣Now online! “Eutopic #macrophages facilitate #endometriosis progression via ferroptosis-mediated release of S100A9” academic.oup.com/molehr/advan...

Uterine #leiomyomas, also known as #fibroids, are benign tumors found in about 60% of pre-menopausal women, and can cause abnormal uterine bleeding, pelvic pain and #infertility.

📣New paper alert on #human sperm protamine proteoforms! Using a refined top-down mass spectrometry protocol, the authors observed significant differences in specific #ProtamineProteoforms related to sperm #chromatin packaging #alterations, #obesity and #aging.

✨The #ESHRE Annual Meeting 2025 is just around the corner! Join us at the #MHRsymposium where MHR’s Editor-in-Chief, @Boiani Michele, and Deputy Editor, @Francesca Duncan, will be hosting the session about Basic principles of ovarian function in vivo and in vitro.

“#Mechanical signal-mediated mitochondria–endoplasmic reticulum contacts modulate Leydig cell testosterone biosynthesis during #testisdevelopment” Free to read 🔗📚 academic.oup.com/molehr/artic...

#Mosaicism is generally defined as heterogeneity of DNA content among the #embryonic cells. Using a novel method enabling simultaneous sequencing of both gDNA and mRNA, this study elucidates the transcriptomic profile of #MosaicEmbryos.

#2024 MHR Early Career Innovator Award winner Dr Olga Astapova! www.linkedin.com/posts/europe...

✨MHR is proud to announce the winner of the #2024 MHR Early Career Innovator Award! Congrats to Dr. Olga Astapova for her study “Paxillin regulates androgen receptor expression associated with granulosa cell focal adhesions” 🥇 academic.oup.com/molehr/artic...

📣📣Calling all early career scientists!! Don’t miss the opportunity to showcase your original research in MHR’s #EarlyCareerInnovatorSeries and join the race for the prestigious #2025 Award! 🥇 Learn more here 👇 academic.oup.com/molehr/pages...

Don’t miss this interesting article on #placental DNA methylation. “Profiling (placental) #DNAmethylation in cell-free DNA across #gestation: the Rotterdam Periconception Cohort” Free to read 🔗📚 academic.oup.com/molehr/artic...

In primates and rodents, the establishment and maintenance of #pregnancy require appropriate development of specialized maternal tissue, the #decidua. Decidual cells arise from uterine stroma, form close relationships with placental structures and facilitate embryo development.

📣New article! “Single-cell metabolomics reveals that #bisphosphoglyceratemutase influences #oocyte maturation through glucose metabolism” 🔗📚 academic.oup.com/molehr/artic...

New article #spotlight about the mechanisms underlying sex differences in the response to, and long-term effects of, early-life environmental exposure.

Just 4 weeks to go until #ESHRE2025!! 👇 www.linkedin.com/posts/europe...

Another fascinating study on #Endometriosis is available in #MHR! academic.oup.com/molehr/artic...

#Endometriosis is an inflammatory condition characterized by the abnormal growth of endometrial tissue outside the uterus, affecting about 10% of women of reproductive age. This condition can severely impair #reproductivehealth and contribute to #infertility.

Here is the #MeetourEditorialBoard series! Spotlight on the Associate Editor Chih-Jen (Lance) Lin #MHR #reproduction #epigenetics #oocytetoembryotransition #femaleinfertility European Society of Human Reproduction and Embryology (ESHRE) Oxford University Press The University of Edinburgh