Sebastián Jara
@jsebajara.bsky.social
📤 381
📥 358
📝 6
Neurobiólogo 🇨🇱 | postdoc @scrippsresearch| Sensory neurons-immune interaction | Axon plasticity
reposted by
Sebastián Jara
1 day ago
Great collaboration with Abel Torres Espín that arose from our work on SCI. Congrats to all involved, including
@jsebajara.bsky.social
, Amanda Bernstein, Marwa Soliman, and Yunuen Moreno López!
www.liebertpub.com/doi/abs/10.1...
loading . . .
Development and Validation of a Machine Learning-Derived Kinematic Deviation Index for the Evaluation of Forelimb in Rodents | AI in Neuroscience
Background: Rodent models are widely used to study neurological conditions and assess forelimb movement to measure functional performance, deficit, recovery, and treatment effectiveness. Traditional a...
https://www.liebertpub.com/doi/abs/10.1177/2997979X251370362
0
1
1
reposted by
Sebastián Jara
Ariel Levine
19 days ago
Does anyone have favorite colors for color blind friendly fluorescence images on a black background where the overlap combinations of 3 colors are important? Magenta/cyan/yellow overlaps are difficult to distinguish (lots of white) Thank you!
2
0
1
Big congrats to Alejandra
@thepenkpanther.bsky.social
on her new SI paper! Kicking off the Mendoza Lab’s work on sensory neuron-immune interactions. Glad to see our image highlighted on their website too!
www.science.org/doi/10.1126/...
loading . . .
Enkephalin-producing regulatory T cells in the skin restrain local inflammation through control of nociception
Regulatory T cells curb noxious sensory signaling to dampen cutaneous inflammation, a neuromodulatory mechanism for immunosuppression.
https://www.science.org/doi/10.1126/sciimmunol.adz6869
21 days ago
0
9
1
reposted by
Sebastián Jara
Misha Ahrens
22 days ago
Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten
@vmsruetten.bsky.social
, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
loading . . .
3
191
76
reposted by
Sebastián Jara
Alejandra Mendoza
25 days ago
After many years of work I’m so happy to share our work on
#scienceimmunology
on how Treg cells modulate nociception to dampen skin inflammation! My handle will make a lot more sense now!🕵🏻♀️
loading . . .
Enkephalin-producing regulatory T cells in the skin restrain local inflammation through control of nociception
Regulatory T cells curb noxious sensory signaling to dampen cutaneous inflammation, a neuromodulatory mechanism for immunosuppression.
https://www.science.org/doi/10.1126/sciimmunol.adz6869
0
19
9
reposted by
Sebastián Jara
about 1 month ago
Very proud that our human PNS atlas is finally published in
@natcomms.nature.com
We found perineurial hyperplasia and lipid-associated nerve macrophages in
#polyneuropathies
. Explore:
pns-atlas.mzhlab.com
A tweetorial 1/13
doi.org/10.1038/s414...
1
16
8
reposted by
Sebastián Jara
Diana Tavares Ferreira
about 1 month ago
This work is finally online as in-press preview! JCI - Cell and molecular profiles in peripheral nerves shift toward inflammatory phenotypes in diabetic peripheral neuropathy
www.jci.org/articles/vie...
loading . . .
JCI - Cell and molecular profiles in peripheral nerves shift toward inflammatory phenotypes in diabetic peripheral neuropathy
https://www.jci.org/articles/view/184075
2
34
15
reposted by
Sebastián Jara
The Transmitter
about 2 months ago
In this month’s “Liftoff,”
@janetsong.bsky.social
shares how she plans to expose trainees to new ideas during lab meetings and Rachel Parkinson emphasizes the importance of taking a step back and reminding yourself about the joys of science. By
@franciscorr25.bsky.social
bit.ly/4mFNGCQ
loading . . .
Liftoff: New lab alerts
Learn about early-career scientists starting their own labs.
https://bit.ly/4mFNGCQ"
1
23
7
reposted by
Sebastián Jara
Brooke Fitzwater, PhD (she/her) 🐟🪱🏳️🌈♾️
2 months ago
As Requested - A Starter Pack of PIs in Biology (or adjacent) fields who are recruiting POSTDOCS! Please don't hesitate to reach out if you wish to be added!
go.bsky.app/4gbXXR3
add a skeleton here at some point
15
123
82
reposted by
Sebastián Jara
Dementia Researcher
3 months ago
The Salk Institute seeks a Full Professor in Neuroimmunology to lead innovative research on nervous and immune system interactions within a collaborative, world-class setting. Closing date: 7th September
www.dementiaresearcher.nihr.ac.uk/job/professo...
loading . . .
Professor in Neuroimmunology - DEMENTIA RESEARCHER
The Salk Institute seeks a Professor in Neuroimmunology to lead innovative research on nervous and immune system interactions within a world-class setting
https://www.dementiaresearcher.nihr.ac.uk/job/professor-in-neuroimmunology-2/
0
4
8
reposted by
Sebastián Jara
Fran Quintana Lab
3 months ago
Our newest paper studying immunosuppressive astrocyte-GBM interactions using RABID-seq is out in @nature.com today! Congrats to Brian Andersen and Camilo Faust Akl!
www.nature.com/articles/s41...
loading . . .
Barcoded viral tracing identifies immunosuppressive astrocyte–glioma interactions - Nature
Using viral barcode tracing to detect interactions between glioblastoma cells and non-malignant astrocytes in patient samples, investigators discovered a pathway that reduces tumour-specific immunity ...
https://www.nature.com/articles/s41586-025-09191-9
0
34
16
reposted by
Sebastián Jara
Tom Gillingwater
4 months ago
New paper from the lab 🚨: Expansion microscopy reveals nano-scale insights into the human neuromuscular junction: Cell Reports Methods
www.cell.com/cell-reports...
loading . . .
Expansion microscopy reveals nano-scale insights into the human neuromuscular junction
Ramadan et al. employ expansion microscopy to visualize neuromuscular junctions in human and mouse muscles. Their findings demonstrate expansion microscopy as an accessible and cost-effective approach...
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375%2825%2900118-3
3
45
14
reposted by
Sebastián Jara
Shane Liddelow
4 months ago
Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉
nyumc.qualtrics.com/jfe/form/SV_...
#Neuroscience
#Postdoc
#ResearchOpportunity
1
61
40
reposted by
Sebastián Jara
⚡️GREG_CORDER⚡️
4 months ago
🧠🐁 Interested in a quick / reliable / reproducible tool to quantify your fluoresently-tagged axons ? Check out AxoDen, a no-coding-needed web app and downloadable GUI ... Designed + developed entriely by the amazing Raquel Adaia Sandoval Ortega
www.eneuro.org/content/12/6...
loading . . .
AxoDen: An Algorithm for the Automated Quantification of Axonal Density in Defined Brain Regions
The rodent brain contains 70,000,000+ neurons interconnected via complex axonal circuits with varying architectures. Neural pathologies are often associated with anatomical changes in these axonal pro...
https://www.eneuro.org/content/12/6/ENEURO.0233-24.2025
1
13
4
reposted by
Sebastián Jara
Doris Krauter
4 months ago
Happy to share my first publication with
@patrikernfors.bsky.social
Lab - all about the DRG: Chromatin accessibility, single cell and spatial RNA sequencing - a great source for everyone interested in sensory neurons and non-neuronal cell of the DRG 😊
add a skeleton here at some point
0
3
1
reposted by
Sebastián Jara
4 months ago
Led by
@scienceyael.bsky.social
& out today in
@natneuro.nature.com
: the brain's fluid-secreting organ — the choroid plexus — can reshape neural development through a powerful, little-known process. & it can be hijacked by serotonergic drugs like LSD. 🧠👇 A thread
rdcu.be/eoaSY
loading . . .
Choroid plexus apocrine secretion shapes CSF proteome during mouse brain development
Nature Neuroscience - The choroid plexus (ChP) provides molecular cues for brain development. However, the underlying mechanisms are unclear. This study identifies an apocrine secretion mechanism...
https://rdcu.be/eoaSY
3
59
25
reposted by
Sebastián Jara
Dr. Ali Barry
4 months ago
We set out to map a detailed proteome of the human DRG and nerve using DIA-MS as a reference to the field, and I think we've succeeded! Lots of proteins (& lots of ion channels), with the data is fully searchable. It's also available on
@sparc.science
sensoryomics.shinyapps.io/Proteomics/
1
6
6
reposted by
Sebastián Jara
Mariko Bennett
5 months ago
Our lab's 1st paper, led by
@fchrisbennett.bsky.social
&
@waisenberg.bsky.social
. A decade thinking how to directly assess the impact of microglia replacement. Yrs of hard work. This kind of work is needed to expand brain disease care for kids & the vision for safer, more effective cell therapy.
add a skeleton here at some point
3
47
20
reposted by
Sebastián Jara
Chen Ran
6 months ago
Lots of recent papers discuss the nucleus of the solitary tract in interoception. In this review, we take a sensory processing perspective on how interoceptive signals are encoded in the NTS:
www.sciencedirect.com/science/arti...
loading . . .
Interoceptive processing in the nucleus of the solitary tract
The interoceptive nervous system continuously monitors the status of visceral organs to synthesize internal perceptions and regulate behavioral and ph…
https://www.sciencedirect.com/science/article/pii/S0959438825000522
0
54
22
reposted by
Sebastián Jara
Carolyn Bertozzi
6 months ago
SCAM ALERT. This is a fake conference that ripped off my and other people’s names to trick people into registering. There is no such conference that I or the others shown were invited or agreed to. We are working to try to get this fraud taken down from the web.
chemsymposia.com
loading . . .
Join Chemsymposia 2026: Research & Innovation | ChemSymposia 2026
Join us at Chemsymposia 2026 to discover groundbreaking research in physics applications. Connect with experts, engage in insightful discussions, and explore our venue, registration details, and speak...
https://chemsymposia.com/
8
198
115
reposted by
Sebastián Jara
Nori Zolboot
6 months ago
✨So happy to see part of my PhD work with
@lippilab.bsky.social
out today in
@cp-neuron.bsky.social
! ✨ We developed new tools to study microRNA-target networks with greater spatial and temporal resolution and found neuronal subtype- and developmental stage-specific roles:
loading . . .
MicroRNA mechanisms instructing Purkinje cell specification
Zolboot et al. introduce DD-T6B and SAP-seq, methods for investigating microRNA function with enhanced spatiotemporal resolution, and identify Purkinje cell-specific microRNAs and targets instructing ...
https://www.cell.com/neuron/fulltext/S0896-6273%2825%2900181-3
4
28
7
reposted by
Sebastián Jara
Lucas Cheadle
6 months ago
journals.biologists.com/dev/article/...
New work from the lab characterizing sensory-dependent transcriptomes in mouse V1 across neuronal and glial cell types. Some fun nuggets in here, and all data publicly available for download and re-analysis. Happy gene hunting!
loading . . .
A single-cell transcriptomic atlas of sensory-dependent gene expression in developing mouse visual cortex
Summary: Single-cell RNA sequencing of developing mouse visual cortex uncovers cell type-specific gene programs induced by sensory experience. All cell types mounted transcriptional responses to the e...
https://journals.biologists.com/dev/article/152/20/dev204244/367517/A-single-cell-transcriptomic-atlas-of-sensory
1
6
3
reposted by
Sebastián Jara
Darragh Duffy
6 months ago
13 chair positions open
@inserm.fr
to lead a junior research group in France covering
#neuroscience
,
#immunology
,
#bioinformatics
,
#bioengineering
,
#biotherapy
,
#public
health
pro.inserm.fr/rubriques/co...
🧪🔬
loading . . .
https://pro.inserm.fr/rubriques/content/calls-for-proposals/inserm-chairs-cpj/cpj
2
36
44
reposted by
Sebastián Jara
Ariel Levine
7 months ago
And science continues… check out our new work led by
@rbrianroome.bsky.social
add a skeleton here at some point
4
18
6
reposted by
Sebastián Jara
Ardem Patapoutian
9 months ago
Hey Neuroscientists 🧠! Heading to San Diego for
#SfN25
in November? Join us for an exciting all-day symposium at
@scripps.edu
in beautiful La Jolla, just a couple of days before the conference. It's free to attend, so register early and plan your travels accordingly! 🧪
0
45
16
reposted by
Sebastián Jara
Theanne Griffith, PhD 🇧🇧👩🏽🔬🇭🇷
9 months ago
Thrilled to share the most recent pub from the Griffith Lab! We show that sodium channels play unique roles in proprioceptive encoding. We also found some really cool effects on skeletal muscle, and a dev dependent role for Nav1.6 in proprioceptive spinal circuits
www.science.org/doi/10.1126/...
loading . . .
Differential encoding of mammalian proprioception by voltage-gated sodium channels
Voltage-gated sodium channels differentially encode mammalian proprioception via distinct cellular localization patterns.
https://www.science.org/doi/10.1126/sciadv.ads6660
12
122
40
reposted by
Sebastián Jara
Christine Beeton
10 months ago
Having a color-blind colleague is a good reminder that we need to be more careful when designing figures for scientific publication 🧪 My lab has found this page especially useful for selecting color palettes, used in combination with different symbols:
thenode.biologists.com/data-visuali...
loading . . .
Color blind friendly palettes for data visualizations with categories
A discussion of color blind friendly palettes for labeling unique catergories in data visualization.
https://thenode.biologists.com/data-visualization-with-flying-colors/research/
42
835
380
reposted by
Sebastián Jara
10 months ago
Here is our latest discovery: macrophages that behave like neurons to help you walk Thanks to Bellardita's lab!
www.nature.com/articles/s41...
loading . . .
Macrophages excite muscle spindles with glutamate to bolster locomotion - Nature
A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle s...
https://www.nature.com/articles/s41586-024-08272-5
0
4
1
reposted by
Sebastián Jara
Ted Price
10 months ago
BOOM! Re-upping our Pain Research Starter Pack since so many people have joined this glorious place in the past week. If you are not on the list and want to be added, let me know and I will add you... I have been doing my best to keep this updated.
#painresearch
go.bsky.app/KboKNhg
add a skeleton here at some point
21
32
19
reposted by
Sebastián Jara
Coleman Lab
10 months ago
Axon Degeneration starter pack now updated. Plenty of room for more so give me a nudge if you’d like to be added.
add a skeleton here at some point
6
14
10
you reached the end!!
feeds!
log in