@andreaserio.bsky.social and I are recruiting a postdoc to lead an exciting MNDA-funded project using multi-omics to study long axons in motor neurons and how they shape susceptibility to #ALS. Get in touch for any questions and apply by 2 December: my.corehr.com/pls/kclrecru...

Why far from being a disadvantage, hostility to people from different races and cultures has now become an active requirement for career advancement on the right of British politics www.adambienkov.co.uk/p/the-racism...

Tl;dr: The first sentence.

This is the state in which waste collectors have left the bins at 14-19 Lichfield Gardens this morning. It has been like that for the past several weeks, after years of (mostly) no issues. This is not haste. This is passive aggression. @richmondcouncil.bsky.social Please report to Serco.

It turns out that "Idiocracy" was way too optimistic.

new lab preprint 👇

First work on kinases from my lab! Working on this project, I often remembered the late Cyrus Chothia who said that if the data doesn’t fit a beautiful model, maybe it’s not the model, maybe you just need more data. :)

“Let’s call it for what it is: bullshit. The truth is, politicians have talked about little else but immigration for decades and in the most dehumanising ways. Polanski added: “Stop the boats’ is all we hear. Well, today I'm saying ‘stop the bullshit’.” www.independent.co.uk/news/uk/home...

Vichy Labour. Deliberately and repeatedly affirming and amplifying the inflammatory far right *lie* of "uncontrolled migration".

Useful reminder from Peter Kellner on the problems we refuse to acknowledge are getting better, and the politics of hopelessness that this breeds open.substack.com/pub/kellnerp...

Retrospectively removing indefinite leave to remain would be immoral and economically damaging. It would tear families apart. Attacking it as ‘potentially illegal’ is completely beside the point. Argue with the (awful) idea. Don’t try ’well, actually you can’t do that’.

mRNA vaccines are one of if not the most studied human inventions in history at this point. It's madness to say that they are somehow not well-understood!

Interested in a sabbatical in Lyon? The Collegium de Lyon provides accommodation and attractive interdisciplinary environment for 1 or 2 semesters. Open to all disciplines. You can be affiliated with any local department/lab. Apply now for 2026-27. collegium.universite-lyon.fr/2026-2027-un...

And now government doctors got my entire channel removed. Don’t worry. I won’t base my entire identity around this or claim it is worse than covid. 😂

If anybody needs advice on good fountain pens, I’d be happy to help.

The guest is David Collum, a rabid conspiracy theorist who is still a professor of chemistry and chemical biology at Cornell. Tenure should probably not be able to protect academics against the consequences of lunacy such as this.

Archaea are often surrounded by bacteria. But is there ever active conflict between the two? Can archaea kill bacteria? If so, how do they do it? Work by @romainstrock.bsky.social shows that some archaea can kill bacteria by secreting peptidoglycan hydrolases. journals.plos.org/plosbiology/...

After nearly twenty years in the making, our attempt at understanding what makes the chaetognath phylum so unique has finally been published! www.nature.com/articles/s41... with #LauraPiovani @dariagavr.bsky.social @alexdemendoza.bsky.social @chemamd.bsky.social and others /1

Wrote a big review with my friend and colleague @varshneylab.social on the state-of-the-art in CRISPR used experimentally in vivo. We wanted to focus on their use in experimental vertebrate animals (apparently passé now but we persist).

Of all the bullshit positions, the one I loathe most is "yOu LiBz mAdE tEh fAsCiSmZ hAppEn" as if fascism is not a cyclical political phenomenon that always has behind it the same violent insecure inadequate men who yearn to dominate and those that support it have no agency or moral responsibility.

There is a growing violent movement which senior politicians and media organisations are now not only seeking to justify, but actively encouraging. Why it's time for politicians to instead start standing up to the wholly illegitimate concerns of the far right www.adambienkov.co.uk/p/illegitima...

I am glad to announce that the #DANIO-CODE Data Coordination Center is back online at a new home: danio-code-dcc.genereg.net Thank you all for your patience and sorry for any inconvenience!

#IZFC2025 #zebrafish #DANIO-CODE data coordination centre is back online. Note changed address: danio-code-dcc.genereg.net

Weight loss improves health but What happens to cells in the fat during weight loss? Intriguingly, immune cell numbers decrease but their activated states persist w chronic inflammatory potential. Beautiful work from neighbors @mrc-lms.bsky.social Will Scott et al www.nature.com/articles/s41...

Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁 Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5

A new study, published today in Nature, reveals the hidden benefits of weight loss on fat tissue. A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.

This is a periodic reminder that every method of research evaluation can be gamed. As this shows, even the cheats can be cheated - if a reviewer outsources their brain to a LLM, the authors will happily try to influence how the LLM does its job. techcrunch.com/2025/07/06/r...

I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org

Sequence-alignment is not the best way to detect conserved cis-regulatory elements? Tobi Zehnder from Vingron-Lab developed #IPP a synteny based algorithm with @ferencmueller.bsky.social, @borislenhard.bsky.social& @da-bar.bsky.social We used it to find conserved enhancers with diverged sequences

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

My heart goes to UK migrants who feel outraged with UK govt's proposals to retroactively extend the qualifying period for permanent residence by 5(!) years. The last Labour govt did the same just by 1 year and it was still shocking and destructive. www.theguardian.com/uk-news/2025... 1/n

Postdoc job opportunity! We're looking for ECR in evolutionary genomics to study the relation between intra-specific gene expression variability, polymorphism, and macro-evolutionary rates. We have the data in 3 fishes & amphioxus, just waiting for your expertise and enthusiasm! tinyurl.com/3aewk286

Mainstream media needs to stop pointing out what "RFK Jr. gets right," because there are many, many trained public health officials who get the same things right without all the batshit crazy eugenics and woo.

Still the overriding question remains unanswered. *Why* do we want to reduce net immigration?

Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social. I'm so excited about this! www.biorxiv.org/content/10.1...

For context, 1.3 billion years ago ancestors of humans separated from the ancestors of fungi.

An excellent place to do a PhD with a great supervisor.

We are so happy to share our latest paper "CHAS infers cell type-specific signatures in bulk brain acetylation studies of neurological and psychiatric disorders". www.cell.com/cell-reports... @ukdri.ac.uk @kingsioppn.bsky.social @imperialbrains.bsky.social

Britain wakes up every day, aims the gun at its feet and pulls the trigger. Just a prolonged exercise in meanspiritedness and self-harm.

🚨PhD alert! In light of everything happening in the world, the Econ Department at Imperial College is conducting a second round of admissions for fall 2025! Applications due April 30, offers in mid-May. Please spread the word! More details: #EconPhD @mondpanther.bsky.social @samasher.bsky.social

I just attended a conference in the US. We had one speaker detained and two others turned away at the border.

I am getting increasingly frustrated by Labour bigwigs speechifying about how the world has changed and we need to be bold and then... not being bold

My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT! For more information see here: gahanlab.com tinyurl.com/34xke35d

What if tech bros had held their nerve? What if ABC had told Trump they’d see him in court? What if Ivy League Universities had defended Columbia? What if big law firms had sued Trump? Cowardice is contagious. Welcome to the Great Grovel www.prospectmagazine.co.uk/world/united...

Highly recommended!

She has lost her mind www.nytimes.com/2025/03/16/o...

Researchers have found that pregnancy in mice leads to the irreversible growth of their small intestine. This research was led by researchers from The Francis Crick Institute, Tomotsune Ameku and Irene Miguel-Aliaga, who were both previously at the LMS.

Great place to work, great project, great boss. Highly recommended!