Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. https://scim.ag/4nTQ3nq

S. copri keeps pace with modern lifestyles Subset of Segatella copri strains have acquired an additional oxygen regulator via horizontal gene transfer, which confers increased oxygen tolerance. These strains are more prevalent in industrialized countries www.cell.com/cell-host-mi...

Die Studie der Erstautor:innen @youssefelmouali.bsky.social & @caroline-tawk.bsky.social ist heute bei @cp-cellhostmicrobe.bsky.social erschienen. Das Team aus der Abteilung von Till Strowig vermutet, dass die Sauerstofftoleranz einen Selektionsvorteil bieten könnte. www.cell.com/cell-host-mi...

Unser Darm ist normalerweise eine sauerstofffreie Zone und viele Bakterien im #Darmmikrobiom vertragen keinen Sauerstoff. Ein HZI-Team zeigt nun aber, dass das #Darmbakterium Segatella copri in industrialisierten Ländern häufiger sauerstofftolerant ist. www.helmholtz-hzi.de/media-center...

New paper out in @cp-cellhostmicrobe.bsky.social! Microbes evolving with modern lifestyles 🧬🦠 S. copri uses PerR to manage oxygen stress, but some strains acquired OxyR via HGT, boosting oxygen tolerance. These strains are enriched in industrialized populations. www.cell.com/cell-host-mi...

Read our new Review Article on antibiotic-induced gut microbiome dysbiosis: Michael Knopp, Camille Goemans et al discuss risks and strategies for mitigation link.springer.com/article/10.1...

New preprint from the Ghigo lab (@jmghigolab.bsky.social): crossfeeding B. theta <--> E. coli within a microfluidics system. Shows spatial structure and oxygen availability can qualitatively transform the nature and ecological outcome of microbial interactions. www.biorxiv.org/content/10.6...

My super department @warwicklifesci.bsky.social is hiring 6 assistant profs in the wake of recent retirements. We're looking for people in microbiology/infection, cellular disease / immunity; environmental biology; and plant/crop science. #MicroSky warwick-careers.tal.net/vx/lang-en-G...

Happy to share our new work on how phages escape bacterial immunity. We show that a phage homing endonuclease drives segmental amplification of anti-defense genes, pointing to a versatile and rapid mode of adaptation. www.nature.com/articles/s41... #PhageSky #MicroSky

Excited to share the first preprint from the lab! We show that ApeA defends against RNA phage infection by cleaving the phage genome: www.biorxiv.org/content/10.6...

Beyond Viral Suppression: How the Right #HIV Drug Helps the Gut Heal Itself @rutgerwalls.bsky.social @fcatalamoll.bsky.social @irsicaixa.es @hospitalclinic.bsky.social#HIV#Microbiome

Our first paper is out today in @natmicrobiol.nature.com! We introduce a prostate organoid model and show that UPEC invades prostate cells via FimH binding to the prostate-specific protein PAPP. A step toward targeted therapies against bacterial prostatitis. 🎉 #UTI #UPEC #Organoids #AMR

New online! Harnessing the microbiome for cancer therapy

RIL-seq boosts the study of sRNAs. Here comes its first application to intracellular bacteria. Plus, 10 years after its characterization, we now present an RNA sponge of Salmonella PinT. Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social! doi.org/10.1093/nar/...

Our preprint on predicting drug resistance in bacteria is now out in @plosbiology.org. We show ignoring phylogenetic structure in genome collections leads to overly optimistic evaluations of machine learning methods for AMR prediction. Work from @yanyingyu.bsky.social with @nwheeler443.bsky.social.

New paper from the lab! Led by Patrick Müller: we show that non-antibiotic compounds — but not macrolide antibiotics — can induce an efflux pump that protects Bacteroidaceae from macrolides. A neat twist on drug–microbe interactions... www.tandfonline.com/doi/full/10....

Check out our new article! Congrats to Michelle Prophete, Alex Mabel and Payton Bowman for their great work! Small RNA promotes negative feedback of the master virulence regulator PhoP by repressing the PhoQ sensor enhancer UgtL in acidic pH | mSphere journals.asm.org/doi/10.1128/...

🔊 Interested in doing a PhD on RNA-binding proteins in an abundant microbiota species and becoming a member of the German Priority Programme “Illuminating Gene Functions in the Human Gut Microbiome”? Apply here: www.uni-wuerzburg.de/karriere/sin...

🧪 #RNAsky If you aren’t using RNAcanvas to draw your RNA structures and explore alternative structures, you are missing out! 56 citations in a year, with multiple ones in top journals like Nature, Science & Cell. Easy to use and packed with unique features! Try it! academic.oup.com/nar/article/...

🧵 New paper alert! Our first dive into non-human hosts: the gut microbiome of the critically endangered lemur Indri indri 🐒🌱 Led by talented MSc student Francisca Labisa-Morais! 📄 @isme-microbes.bsky.social academic.oup.com/ismej/advanc...

Human populations with less industrialized lifestyles may not experience inflammaging, a chronic low-grade inflammation that is linked with ageing, according to research published in @nataging.nature.com: #Ageing

www.sciencedirect.com/science/arti... Nearly missed my bus stop reading this fascinating review :)

I'm happy to share the first publication from my lab @hoerlab.bsky.social, now out in @narjournal.bsky.social! I take a look at the biology of RNA phages, focusing on how meta-omics methods are discovering new RNA phage families and bacterial defense strategies. #PhageSky doi.org/10.1093/nar/...

#weekendreading🔬📑 A geological timescale for bacterial evolution and oxygen adaptation @science.org #microsky www.science.org/doi/10.1126/...

I am very excited to share our latest publication on the effect of systemic #endotoxin on intestinal #microbiota spearheaded by the brilliant Sanne Kroon at the Hardt lab @eth-dbiol.bsky.social @ethzurich.bsky.social @naturecomms.bsky.social 👉🏼 rdcu.be/eelLn

I have been teaching classes on the gut #microbiome for almost 20 years and always struggled to have a good book to recommend. Finally there is one. Fergus Shanahan's "Fast Facts: The Gut Microbiome" provides expert insight, is brilliant, and it is free. doi.org/10.1159/isbn...

Our review on the acquisition and transmission of the human microbiome, now out @naturerevmicro.bsky.social 🦠 🔄 This was a fun writing process with @vheidrich.bsky.social and Nicola Segata! See Vitor's summary thread below:

Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 🧪🧫🦠 www.nature.com/articles/s42... #metagenomics #microbiome #microbiomesky So what is MEDI? A combination of two things:

📣Fully funded PhD position available in our lab at @uniwuerzburg.bsky.social, in collaboration with Dr. Connolly at Newcastle University (@ruamicro.bsky.social). "Dissecting the RNA-centric landscape of microbiota-pathogen interactions in the gut”. 🦠 Apply here: www.uni-wuerzburg.de/karriere/sin...

How did microbes obtain energy for growth when oxygen was scarce, before the Great Oxidation Event? The study of microbes in hot springs identifies pathways involving certain cytochrome oxidases that may have played a crucial role in early microbial evolution 🦠🧪 www.nature.com/articles/s41...

Starting my Bluesky adventure by highlighting a new paper from the lab!

Interested in collecting, sharing, and interacting with large collections of bacterial functional genomics data (RNA-seq, Tn-seq/TraDIS, etc.)? Check out our new web platform, Micromix, with case studies for Salmonella and Bacteroides! 🧫🧬🖥️🧪 Thread 1/n academic.oup.com/gigascience/...

Happy to share our new paper in @naturemicrobiol.bsky.social on mapping spatial relationships of the human gut microbiome. We identified distinct spatial hubs between gut bacteria that reflect sub-community assemblies at the micron-scale. Led by Miles Richardson & co. www.nature.com/articles/s41...

Keeping Up With the Boost Fellows, Freiburg We visited cognitive neuroscientist and Boost fellow @denizkumral.bsky.social in Freiburg. Deniz moved there from the @mpicbs.bsky.social in Leipzig to the Imaging Memory and Consolidation Lab of Monika Schönauer at @uni-freiburg.de.

OUT NOW: Microbiota-derived succinate promotes EHEC virulence via lysine succinylation #microsky 🧪 www.nature.com/articles/s41...

New in @nature.com Expanding the human gut microbiome atlas of Africa www.nature.com/articles/s41...

This week @science.org Sarfatis, Moffitt et al. from @bostonchildrens.bsky.social @harvardmed.bsky.social @broadinstitute.org Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/... #microsky #microbial #microbiology #genomics #transcriptomic 🦠🧫

📢 Thrilled to share our latest research! Certain gut bacteria may protect against typhoid fever by producing short-chain fatty acids www.medrxiv.org/content/10.1...

🦠🔬Our paper which maps the composition and function of the gut #microbiome in children throughout 1-18 months of life in rural Zimbabwe, is out today in @NatureComms! A quick 🧵on what we found 👇 https://www.nature.com/articles/s41467-023-36135-6#microbiome @MangesLab @QMULBartsTheLon...

Leeds study of 19 pts at-risk for RA (ACPA+ & arthralgia) finds low-diversity gut microbiome & in the 10 mos preceding the transition to RA, microbiome becomes more unstable w/ accumulation of Prevotellaceae, particularly Prevotella copri

We’re thrilled that our first paper on the Human Microbiome Compendium, an integrated dataset of over 168,000 uniformly processed human gut microbiome samples, is officially out today in Cell! @richabdill.com @blekhman.bsky.social www.cell.com/cell/fulltex...

NEW COMMENT: Microbiome science needs more microbiologists @abaumler.bsky.social and Lauren Radlinski argue that integrating microbiologists and fundamental microbiological concepts should help advance microbiome science www.nature.com/articles/s41...

Interested in predicting AMR in bacteria? We show ignoring phylogenetic structure in genome collections leads to overly optimistic evaluations of machine learning methods for AMR prediction. With @nwheeler443.bsky.social and former PhD student Yanying Yu. 🦠🧫🧬🖥️🧪 www.biorxiv.org/content/10.1...

It was time to move here! Check out our recent paper on the essential role of a small RNA for Segatella copri gut colonization. Mechanistic insights on the lifestyle of the mysterious (but incredibly abundant) Segatella/Prevotella copri in the gut. www.cell.com/cell-host-mi...

Did 6-carbon sugars arrive late to the picnic? This one's fun: Steffen Lindner & Markus Ralser make a case for the primacy of pentose (5-carbon) metabolism in early evolution >4 billion years ago @plosbiology.org journals.plos.org/plosbiology/...