I've been writing Advent Calendar posts about Pixie the Elf for a few years now. So I thought it was time she had her own website. pixie.perlhacks.com

I've always loved the openness and collegiality of our C. elegans community 🪱, but this perspective really helps emphasize just *how important* those traits are for scientific progress. A true tribute to how curiosity-driven science leads to innovation! 🙌

Wow! This looks fascinating

A potent and plain-spoken defence of DEI in science - from the experts. Representation *matters*.

John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale, which has paved the way for quantum computing. ⚛️🧪

Today’s NYT Spelling Bee Puzzle seems replete with answers for a former #celegans #genetics fan . . .

Are you an early career scientist who wants to get specialist training in C. elegans model for your laboratory research? we co-organize again the EMBO C. elegans course! Do not miss applying!

Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans journals.biologists.com/dev/article/...

Fun fact: diluted tattoo inks and washes make pretty decent carbon sources for NTMs.

You had me at "supergiant cannibals." 😱 Gotta love the world of ciliates. Good🧵⬇️

As a member of the Toronto Perl Mongers I volunteered at the TPRC held in Toronto in 2023. This blog post from Bryan Katz relates his experience with Perl in general, and specifically at that conference #relatable #perl www.perl.com/article/my-g...

Exciting new study showing extensive Argonaute protein family gain, loss, neofunctionalization + more among species, by PhD student Daniel Fusca with @katjakasimatis.bsky.social + Hongyu Zhu; Now out @genomebiolevol.bsky.social #celegans #rna doi.org/10.1093/gbe/...

Not again?!?

Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.05.13.653874v1

Alternative splicing across the C. elegans nervous system www.nature.com/articles/s41...

Whoah!!

The Provisional Mortality statistics have been updated by the Australian Bureau of Statistics (ABS), up to January 2025. Here are the deaths where the underlying cause of death was certified by a doctor as COVID-19 (22,357 deaths). #COVID19 #Australia 🧵

The US has cut the equivalent of 3X the total annual CIHR budget so far this year, revealing both how low the CIHR budget is and how utterly draconian the White House has treated one of the most precious and successful institutions the US has ever built.

Huge thanks to Federico Gueli for his tips on new lineages to watch out for, eg bsky.app/profile/siam... 🧵

With the LP.8.1.* variant dominant from the global perspective, it is time to ponder which variant might drive the next wave. The leading contenders at this point are XDV.* (led by NB.1.8.1), and XFG.*. #COVID19 #NB_1_8_1 #XFG 🧵

@augustorendon.bsky.social It was such a good idea now everyone is copying you. Who knew?

🪱 Worm people! C. elegans Mentor Match sign-ups close May 8: 👩‍🔬 Be matched with a mentor → custom career guidance 🤝 Join a peer group → swap tips & stay accountable ✨ Both → double support Tell your lab mates and help us grow the program!

Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans. Email or DM me to find out more. Please share & repost!

The “BOBS” category in today’s puzzle seems slightly anti- #Celegans What about HERMAN, WATERSTON, or HERMAN?

That seems like such a shallow depiction of all of C. elegans’ behaviours and strengths. Clearly he never spent an hour watching some crawl around a plate. Oh well, who has time to educate all of the plebes.

Are you using Bluesky primarily as a source for links but are overwhelmed by the massive inflow of posts and doom? I wrote a small #Emacs package to fetch links from your #Bsky feed, sort them by frequency and time posted, and present them in an #orgmode buffer. github.com/rtrppl/hotsky

That’s a wrap on our first-ever Full Length 16S rRNA @pacbio.bsky.social Sequencing & Bioinformatics course! 🧪💻 From lab bench to species-level insight, participants processed their own data through QC, DADA2, taxonomic annotation & more, to create figures like this! 🧬👇

📝 New Bioconductor blog post on Outreachy internship experience by Kate Rasheed and Aleru Divine, mentored by the #bugsigdb team. Check it out here: blog.bioconductor.org/posts/2025-0... #Bioconductor #Bioinformatics #Outreachy #Internship #OpenSource #OpenScience

Pairing? Meiotic Pairing Centers on nematode chromosomes? Sweet!

30 years after I first puzzled over my results with Ras mutations, Ariel Pani’s group has generated a plethora of cool new tools to dissect how FGF signaling directs #Celegans sex myoblast migration - and it doesn’t seem to be acting through the usual suspects!

Carolyn Elya Named a 2025 Searle Scholar #academicsky #SciComm 🧬 🧪 www.mcb.harvard.edu/department/n... @zombiflied.bsky.social @fleshball.bsky.social @hekstralab.bsky.social @rachellegaudet.bsky.social @microbiometcell.bsky.social @dulaclab.bsky.social @neurovenki.bsky.social

We made it to the cover! :)

Cool job working on veterinary-based Phylogenetic Trees at Iowa State University in Ames, IA. careers.iscb.org/jobs/view/9027

Check out our new Youtube video about contributing to Reactome! Learn more by watching our youtube video, created by Cristoffer Sevilla! www.youtube.com/watch?v=P5Gi... Like and subscribe to our Youtube channel for more updates! 🖥️🧬

I feel like this is the right time to bring back this awesome feat of AI. C. elegans with neurons labelled in green as interpreted by ChatGPT.

Early resolution of sister chromatids during C. elegans meiosis https://www.biorxiv.org/content/10.1101/2025.03.29.646130v1

We are excited to welcome Prof Andrew Chisholm of UCSD for his talk on “Multiscale patterning outside the cell: the C. elegans model extracellular matrix” Friday, Apr 4 at 11am in RW432. See you there! csb.utoronto.ca/event/csb-se...

This opening plenary has been great; a really great overview of the challenges and solutions of applying data standards to clinical and research genomics.

A novel epifluorescence microscope design and soft-ware package to record naturalistic behaviour and cell activity in freely moving Caenorhabditis elegans. https://www.biorxiv.org/content/10.1101/2025.03.21.644605v1

'Seeing students engage with complex challenges and develop into confident engineers and scientists is truly inspiring.' CEB Professor Ewa Marek has been recognised with a Pilkington Prize! https://www.ceb.cam.ac.uk/news/ewa--marek-pilkington #DrivenByCuriosity #DrivingChange 🧪⚙️🌱🔋   #Cambridge

“Each moment, each day, people don’t access their antiretroviral treatment is clearly a recipe for a disaster.” My colleague @cohenjon.bsky.social spoke to John Nkengasong, the outgoing head of PEPFAR 🧪 #IDsky

All kinds of wonderfullness where I am working: www.ucsc.edu/improving-li...

The US NIH are on lockdown... grinding research and higher education sectors to a halt. Access to trustworthy information is among the most important preconditions for safeguarding democracy. Five things scientists can do to fight the rise of fascism. 🧪 conservechange.medium.com/five-things-...

So, how are things going, anyway?

@enchiladalaura.bsky.social “Worm Atlas editor?!?” Sounds like a dream job (I am being serious, but can understand why folks who know me might doubt that). How come the guidance counselor in High School didn’t have this on their list of careers?

If you see this, post a vampire. P. pacificus biting C. elegans.

It’s like today’s NYT Mini Crossword was customized for me!

From @bioinfoadv.bsky.social | blast2galaxy: a CLI and Python API for BLAST+ and DIAMOND searches on @galaxyproject.bsky.social servers | 🧬 🖥️ 🧪 #bioinformatics #UseGalaxy | academic.oup.com/bioinformati...

25 years on: The Perl Advent Calendar, Mark Fowler looks back at where we were, and what we’ve become. #Perl perladvent.org/2024/2024-12-24 🧪🧬🖥